esperamicin A1
- CAS No.
- 99674-26-7
- Chemical Name:
- esperamicin A1
- Synonyms
- speramicin;esperamicin A1;Eesperamicin A1;Esperamicin A1 (BMY 28175);Carbamic acid, N-[(1R,4Z,8S,12S,13E)-8-[[4,6-dideoxy-2-O-[2,4-dideoxy-3-O-methyl-4-[(1-methylethyl)amino]-α-L-threo-pentopyranosyl]-4-[[(2,6-dideoxy-4-S-methyl-4-thio-β-D-ribo-hexopyranosyl)oxy]amino]-β-D-glucopyranosyl]oxy]-12-[[2,6-dideoxy-3-O-[4,5-dimethoxy-2-[(2-methoxy-1-oxo-2-propen-1-yl)amino...
- CBNumber:
- CB21371312
- Molecular Formula:
- C59H80N4O22S4
- Molecular Weight:
- 1325.54
- MDL Number:
- MFCD34469160
- MOL File:
- 99674-26-7.mol
- MSDS File:
- SDS
| Density | 1.43±0.1 g/cm3(Predicted) |
|---|---|
| pka | 6.67±0.70(Predicted) |
| CAS DataBase Reference | 99674-26-7 |
| FDA UNII | PLX8T21X8G |
esperamicin A1 Chemical Properties,Uses,Production
Uses
Esperamicin A1, as an extremely potent antitumor antibiotic, is isolated from cultures of Actinomadura verrucosospora. Esperamicin A1 can be used for the research of antitumor[1]. Eesperamicin A1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Definition
ChEBI: A naturally occurring antibiotic and antitumor agent isolated from Actinomadura verrucosopora. Its chemical structure consists of a core bicyclo[7.3.1]tridecadiynene moiety containing a 1,5-diyn-3-ene as part of a ten-membered ring, a lpha,beta-unsaturated ketone with a bridgehead double bond and an attached allylic trisulfide. This ring system is attached at one end by a trisaccharide moiety and at the opposite end by a 2-deoxy-L-fucose-anthra ilate moiety. The trisaccharide consists of a hydroxyamino sugar which is connected to a isopropylamino sugar through a glycosidic linkage and a thiomethyl sugar through an NH1O linkage.
References
[1] Lam, K. S., et al. Biosynthesis of esperamicin A1, an enediyne antitumor antibiotic. Journal of the American Chemical Society, 115(26), 12340–12345.
esperamicin A1 Preparation Products And Raw materials
Raw materials
Preparation Products
esperamicin A1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Minbiotech Co., Ltd. | +8617315815539 | sales@minbiotech.com | CHINA | 129 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15233 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3135 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 5221 | 58 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 | sales@sunlidabio.com | China | 3239 | 55 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3467 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7787 | 56 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4621 | 55 | |
| Wellman Pharmaceutical Group Limited | 027-83778875 15807197853 | 15807197853@163.com | China | 3935 | 58 |
99674-26-7(esperamicin A1)Related Search:
1of4