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Myosin-IN-1

Myosin-IN-1 structure

CAS No.: 849011-39-8

Chemical Name:: Myosin-IN-1

Synonyms: Myosin-IN-1;Thiourea, N-(6-ethyl-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)-N′-(1-methylethyl)-

CBNumber:: CB213898469

Molecular Formula:: C12H16N4OS2

Molecular Weight:: 296.41

MDL Number:

MOL File:: 849011-39-8.mol

Last updated:2025-05-19 13:47:34

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Myosin-IN-1 Properties

Boiling point	442.208±47.00 °C(Press: 760.00 Torr)(predicted)
Density	1.401±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka	7.908±0.20(predicted)

Myosin-IN-1 Chemical Properties, Uses, Production

Uses

Myosin-IN-1 (compound F10) is a Myosin inhibitor that specifically targets cardiac myosin. Myosin-IN-1 stabilizes the biochemical and structural closed state of the cardiac myosin motor domain and reduces myocardial force production and calcium sensitivity in vitro. Myosin-IN-1 acts as a negative inotropic agent in isolated Langendroff-perfused rat hearts, reducing stress in isolated myofilaments and left ventricular pressure development. Myosin-IN-1 can be used in heart failure research[1].

References

[1] Parijat P, et al. Discovery of a novel cardiac-specific myosin modulator using artificial intelligence-based virtual screening. Nat Commun. 2023 Nov 24;14(1):7692. DOI:10.1038/s41467-023-43538-y

Myosin-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

Myosin-IN-1 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

849011-39-8 (Myosin-IN-1) Related Search:

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Myosin-IN-1 Thiourea, N-(6-ethyl-4-oxothieno[2,3-d]pyrimidin-3(4H)-yl)-N′-(1-methylethyl)- 849011-39-8