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ChemicalBook >> CAS DataBase List >>1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone Structure
1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone structure
CAS No.
487-49-0
Chemical Name:
1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone
Synonyms
Ononetin;2,4-Dihydroxyphenyl 4-Methoxybenzyl Ketone;4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone;2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone;Ethanone,1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)-;2’, 4’-Dihydroxy-2(4-methoxyphenyl) acetophenone (Ononetin);Inhibitor,Transient receptor potential channels,Ononetin,inhibit,Ca2+,TRP Channel,TRPM3,deoxybenzoin
CBNumber:
CB21458187
Molecular Formula:
C15H14O4
Molecular Weight:
258.27
MDL Number:
MFCD00020119
MOL File:
487-49-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
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1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone Properties

Melting point 158.0 to 162.0 °C
Boiling point 464.7±14.0 °C(Predicted)
Density 1.275±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility soluble in Methanol
form powder to crystal
pka 7.65±0.35(Predicted)
color White to Light yellow to Dark green
FDA UNII 4S084Z7YS4

SAFETY

Risk and Safety Statements

Symbol(GHS)  Environment (GHS09)
GHS09
Signal word  Warning
Hazard statements  H400
Precautionary statements  P273-P391-P501
RTECS  KM5775350
HS Code  2914.50.3000

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D4816 2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone >98.0%(T) 487-49-0 1g $276 2025-07-31 Buy
TCI Chemical D4816 2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone >98.0%(T) 487-49-0 200mg $80 2025-07-31 Buy
Cayman Chemical 35813 Ononetin ≥98% 487-49-0 25mg $43 2026-04-30 Buy
Cayman Chemical 35813 Ononetin ≥98% 487-49-0 50mg $82 2026-04-30 Buy
Cayman Chemical 35813 Ononetin ≥98% 487-49-0 100mg $152 2026-04-30 Buy
Product number Packaging Price Buy
D4816 1g $276 Buy
D4816 200mg $80 Buy
35813 25mg $43 Buy
35813 50mg $82 Buy
35813 100mg $152 Buy

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone Chemical Properties, Uses, Production

Uses

Ononetin is a potent and selective transient receptor potential TRMP3 blocker and may represent a novel concept for analgesic treatment.

Definition

ChEBI: 1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone is a stilbenoid.

Preparation

Preparation by condensation of p-methoxyphenyl-acetonitrile with resorcinol (Hoesch reaction).

in vivo

Ononetin (10 mg/kg, i.p.) treatment completely reverses established Freund's Complete Adjuvant (FCA)-induced heat hypersensitivity, demonstrating that the loss of hypersensitivity in Trpm3-/- mice is unlikely to be caused by developmental or compensatory mechanisms and suggests that TRPM3 may be a tractable target for inflammatory pain[2].

IC 50

TRPM3: 0.3 μM (IC50)

storage

Store at +4°C

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

7-Hydroxy-3-(4-methoxyphenyl)-2-methyl-4H-chromen-4-one 1-(2-Hydroxy-4-methoxyphenyl)-2-(4-methoxyphenyl)ethanone

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone Suppliers

Global Suppliers ( 93)
Supplier Tel Email Country ProdList Advantage
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75
TCI AMERICA 800-4238616 sales@tciamerica.com Americas 23636 75
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 1999 58
AdooQ Bioscience CHINA 025-58849295 info@adooq.cn China 2981 60
Shanghai Chenzhu Pharmaceutical Co., Ltd. 13162380607 1696175688@qq.com China 834 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Supplier Advantage
TCI (Shanghai) Development Co., Ltd. 81
BOC Sciences 65
TOKYO CHEMICAL INDUSTRY CO., LTD. 80
TCI Europe 75
TCI AMERICA 75
Bide Pharmatech Ltd. 60
HangZhou YuHao Chemical Technology Co., Ltd. 58
AdooQ Bioscience CHINA 60
Shanghai Chenzhu Pharmaceutical Co., Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58

View Latest Price from 1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ononetin pictures 2026-08-08 Ononetin
487-49-0
 $47.00-139.00 98.06% 10g TargetMol Chemicals Inc.
  • Ononetin pictures
  • Ononetin
    487-49-0
  • $47.00-139.00
  • 98.06%
  • TargetMol Chemicals Inc.

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone Spectrum

1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone(487-49-0)1HNMR

487-49-0 (1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone) Related Search:

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Ethanone,1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)- 2,4-Dihydroxyphenyl 4-Methoxybenzyl Ketone 2’, 4’-Dihydroxy-2(4-methoxyphenyl) acetophenone (Ononetin) 4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone Inhibitor,Transient receptor potential channels,Ononetin,inhibit,Ca2+,TRP Channel,TRPM3,deoxybenzoin 2',4'-Dihydroxy-2-(4-methoxyphenyl)acetophenone Ononetin 487-49-0