Minaprine dihydrochloride
- CAS No.
- 25953-17-7
- Chemical Name:
- Minaprine dihydrochloride
- Synonyms
- Ag 620;Agr 620;Agr 1240;Nsc305742;Minaprine dihydrochloride, 10 mM in DMSO;4-Methyl-N-(2-morpholinoethyl)-6-phenylpyridazin-3-amine dihydrochloride;Monoamine Oxidase,MAO,Minaprine dihydrochloride,inhibit,Inhibitor,Minaprine;Pyridazine, 4-methyl-3-[(2-morpholinoethyl)amino]-6-phenyl-, dihydrochloride;4-Morpholineethanamine, N-(4-methyl-6-phenyl-3-pyridazinyl)-, dihydrochloride;Morpholine, 4-[2-[(4-methyl-6-phenyl-3-pyridazinyl)amino]ethyl]-, dihydrochloride
- CBNumber:
- CB21485680
- Molecular Formula:
- C17H24Cl2N4O
- Molecular Weight:
- 371.30466
- MDL Number:
- MFCD00083410
- MOL File:
- 25953-17-7.mol
- MSDS File:
- SDS
| Melting point | 182° |
|---|---|
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 100 mg/mL (269.32 mM) |
| form | Solid |
| color | White to off-white |
| EWG's Food Scores | 1 |
| FDA UNII | 82Y7NT6DFT |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Toxicity | LD50 intraperitoneal in mouse: 63mg/kg |
Minaprine dihydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-4347 | Minaprine dihydrochloride 99.90% | 25953-17-7 | 100mg | $54 | 2026-06-04 | Buy |
| Biosynth | BM166417 | Minaprine hydrochloride | 25953-17-7 | 100mg | $250 | 2026-06-04 | Buy |
| aablocks | AA00BF3H | 4-Methyl-N-(2-morpholinoethyl)-6-phenylpyridazin-3-amine dihydrochloride | 25953-17-7 | 100mg | $53 | 2026-05-28 | Buy |
| Crysdot | CD31002489 | Minaprine dihydrochloride 98+% | 25953-17-7 | 100mg | $49 | 2026-05-27 | Buy |
| Arctom | HY-B0884A | Minaprine dihydrochloride 99.90% | 25953-17-7 | 100mg | $48 | 2026-05-26 | Buy |
Minaprine dihydrochloride Chemical Properties, Uses, Production
Originator
Cantor,Clin Midy,France,1979
Uses
Antidepressant.
Manufacturing Process
(a) Preparation of the free base: A mixture comprising 0.1 mol (20.4 g) of 3-chloro-4-methyl-6-phenylpyridazine and 0.2 mol (26.2 g) of N-(2-aminoethyl)-morpholine in 100 ml of n-butanol, with a pinch of copper powder, was heatedunder reflux for 12 hours. At the end of this time, the hot solution was pouredinto 200 ml of cold water. The resulting mixture was filtered through asintered glass filter and the precipitate washed with ether. The filtrate and theether washings were placed in a separating funnel and extracted with two 150ml portions of ether. The ethereal layer was then extracted with about 250 mlof N sulfuric acid.
The acid solution was made alkaline with a 10% aqueous solution of sodiumcarbonate, and left to crystallize overnight.
The solution was filtered, yielding the colorless needles which wererecrystallized from isopropanol. The yield was 15 g (53%).
(b) Preparation of the hydrochloride: The base was dissolved in the smallestamount possible of anhydrous acetone. Double that volume of anhydrousether was added, and a stream of hydrogen chloride gas was passed throughthe solution. The hydrochloride salt obtained was recrystallized from absolutealcohol. The yield after recrystallization was 17 g (90%).
Therapeutic Function
Antidepressant
Minaprine dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Minaprine dihydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4648 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Luofa Biochemical Technology Co., Ltd. | 021-51111890 15317326293 | sales@molnova.com | China | 4183 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
View Latest Price from Minaprine dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Minaprine dihydrochloride
25953-17-7
|
$41.00 | 99.43% | 10g | TargetMol Chemicals Inc. |
-
- Minaprine dihydrochloride
25953-17-7
- $41.00
- 99.43%
- TargetMol Chemicals Inc.
