ChemicalBook >> CAS DataBase List >>2-(4-bromo-2-chlorophenyl)acetic acid

2-(4-bromo-2-chlorophenyl)acetic acid

CAS No.
916516-89-7
Chemical Name:
2-(4-bromo-2-chlorophenyl)acetic acid
Synonyms
4-Bromo-2-chlorobenzeneacetic acid;Benzeneacetic acid, 4-broMo-2-chloro-;2-(4-bromo-2-chlorophenyl)acetic acid
CBNumber:
CB21557053
Molecular Formula:
C8H6BrClO2
Molecular Weight:
249.49
MDL Number:
MFCD11847409
MOL File:
916516-89-7.mol
MSDS File:
SDS
Last updated:2026-05-27 23:59:55
Product description Number Pack Size Price
2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 264516 1g $482
2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 264516 2g $658
2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 264516 5g $852
2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 264516 10g $1104
2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 264516 25g $1663
More product size

2-(4-bromo-2-chlorophenyl)acetic acid Properties

Boiling point 353.2±27.0 °C(Predicted)
Density 1.720±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 3.92±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P312
HS Code  2918999090

2-(4-bromo-2-chlorophenyl)acetic acid price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 1g $482 2026-06-03 Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 2g $658 2026-06-03 Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 5g $852 2026-06-03 Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 10g $1104 2026-06-03 Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 25g $1663 2026-06-03 Buy
Product number Packaging Price Buy
264516 1g $482 Buy
264516 2g $658 Buy
264516 5g $852 Buy
264516 10g $1104 Buy
264516 25g $1663 Buy

2-(4-bromo-2-chlorophenyl)acetic acid Chemical Properties,Uses,Production

Synthesis

(4-BROMO-2-CHLOROPHENYL)ACETONOTRILE

67197-54-0

2-(4-bromo-2-chlorophenyl)acetic acid

916516-89-7

In a round-bottomed flask, 2-chloro-4-bromophenylacetonitrile (19.0 g, 82.4 mmol, 1.0 eq.) was dissolved in water (196 mL), followed by the addition of potassium hydroxide (KOH, 23.1 g, 412 mmol, 5.0 eq.). The reaction mixture was heated to reflux and stirred for 12-18 hours. After completion of the reaction, it was cooled to room temperature and washed with ethyl acetate (EtOAc) to remove organic impurities. The aqueous phase was acidified with 2N hydrochloric acid to pH < 2 and subsequently extracted with ethyl acetate (150 mL x 3). The organic phases were combined, washed with saturated sodium chloride solution (brine), dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to afford 2-(4-bromo-2-chlorophenyl)acetic acid (S3) as brown crystals (19.1 g, 93% yield). The product characterization data were in agreement with literature reports. [20]

References

[1] Tetrahedron Letters, 2016, vol. 57, # 3, p. 449 - 451
[2] Patent: WO2013/43232, 2013, A2. Location in patent: Paragraph 00502
[3] Patent: EP2017257, 2009, A1. Location in patent: Page/Page column 21-22
[4] Patent: JP2015/231988, 2015, A. Location in patent: Paragraph 0361; 0362

67197-54-0
916516-89-7
Synthesis of 2-(4-bromo-2-chlorophenyl)acetic acid from (4-BROMO-2-CHLOROPHENYL)ACETONOTRILE
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View Lastest Price from 2-(4-bromo-2-chlorophenyl)acetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(4-bromo-2-chlorophenyl)acetic acid pictures 2019-07-06 2-(4-bromo-2-chlorophenyl)acetic acid
916516-89-7
$1.00 1kg 99% 200kg Career Henan Chemical Co

2-(4-bromo-2-chlorophenyl)acetic acid Spectrum

2-(4-bromo-2-chlorophenyl)acetic acid Benzeneacetic acid, 4-broMo-2-chloro- 4-Bromo-2-chlorobenzeneacetic acid 916516-89-7