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2-(4-bromo-2-chlorophenyl)acetic acid

2-(4-bromo-2-chlorophenyl)acetic acid Structure
2-(4-bromo-2-chlorophenyl)acetic acid structure
CAS No.
916516-89-7
Chemical Name:
2-(4-bromo-2-chlorophenyl)acetic acid
Synonyms
4-Bromo-2-chlorobenzeneacetic acid;Benzeneacetic acid, 4-broMo-2-chloro-;2-(4-bromo-2-chlorophenyl)acetic acid
CBNumber:
CB21557053
Molecular Formula:
C8H6BrClO2
Molecular Weight:
249.49
MDL Number:
MFCD11847409
MOL File:
916516-89-7.mol
MSDS File:
SDS
Last updated:2026-05-27 23:59:55
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2-(4-bromo-2-chlorophenyl)acetic acid Properties

Boiling point 353.2±27.0 °C(Predicted)
Density 1.720±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 3.92±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P312
HS Code  2918999090

2-(4-bromo-2-chlorophenyl)acetic acid price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 1g $482 2026-06-03 Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 2g $658 2026-06-03 Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 5g $852 2026-06-03 Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 10g $1104 2026-06-03 Buy
Usbiological 264516 2-(4-Bromo-2-chlorophenyl)acetic acid Asreported 916516-89-7 25g $1663 2026-06-03 Buy
Product number Packaging Price Buy
264516 1g $482 Buy
264516 2g $658 Buy
264516 5g $852 Buy
264516 10g $1104 Buy
264516 25g $1663 Buy

2-(4-bromo-2-chlorophenyl)acetic acid Chemical Properties,Uses,Production

Synthesis

(4-BROMO-2-CHLOROPHENYL)ACETONOTRILE

67197-54-0

2-(4-bromo-2-chlorophenyl)acetic acid

916516-89-7

In a round-bottomed flask, 2-chloro-4-bromophenylacetonitrile (19.0 g, 82.4 mmol, 1.0 eq.) was dissolved in water (196 mL), followed by the addition of potassium hydroxide (KOH, 23.1 g, 412 mmol, 5.0 eq.). The reaction mixture was heated to reflux and stirred for 12-18 hours. After completion of the reaction, it was cooled to room temperature and washed with ethyl acetate (EtOAc) to remove organic impurities. The aqueous phase was acidified with 2N hydrochloric acid to pH < 2 and subsequently extracted with ethyl acetate (150 mL x 3). The organic phases were combined, washed with saturated sodium chloride solution (brine), dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to afford 2-(4-bromo-2-chlorophenyl)acetic acid (S3) as brown crystals (19.1 g, 93% yield). The product characterization data were in agreement with literature reports. [20]

References

[1] Tetrahedron Letters, 2016, vol. 57, # 3, p. 449 - 451
[2] Patent: WO2013/43232, 2013, A2. Location in patent: Paragraph 00502
[3] Patent: EP2017257, 2009, A1. Location in patent: Page/Page column 21-22
[4] Patent: JP2015/231988, 2015, A. Location in patent: Paragraph 0361; 0362

2-(4-bromo-2-chlorophenyl)acetic acid synthesis

67197-54-0
916516-89-7
Synthesis of 2-(4-bromo-2-chlorophenyl)acetic acid from (4-Bromo-2-chlorophenyl)acetonotrile

2-(4-bromo-2-chlorophenyl)acetic acid Preparation Products And Raw materials

Raw materials

(4-Bromo-2-chlorophenyl)acetonotrile 4-Bromo-2-chlorobenzoic acid (4-Bromo-2-chlorophenyl)methanol Water Potassium hydroxide
4-Bromo-1-bromomethyl-2-chloro-benzene

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Preparation Products

Methyl 2-(4-broMo-2-chlorophenyl)acetate 4-Bromo-2-chlorobenzeneacetic Acid Ethyl Ester

2-(4-bromo-2-chlorophenyl)acetic acid Suppliers

Global( 76)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9849 55
Hubei XinyuanShun Chemical Co., Ltd. 13971561712, 13995564702, 027-50664929 hbeixys2001@163.com China 3110 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
Changzhou Tianrui Pharmaceutical Technology Co., Ltd. 0519-85386832 13382812559 sales@cztrchem.com China 1211 56
Shanghai DongYang Biotechnology Co., Ltd. 18657622632 chemsharker@126.com China 371 55
Changzhou Anxuan Chemical, Co., Ltd. 13912302692 sales@anxuanchem.com China 4824 58
Supplier Advantage
Shanghai Hanhong Scientific Co.,Ltd. 64
Hangzhou Sage Chemical Co., Ltd. 58
Shanghai Topbiochem Technology Co., Ltd 58
Amatek Scientific Co. Ltd. 55
Hubei XinyuanShun Chemical Co., Ltd. 55
Bide Pharmatech Ltd. 60
Shanghai HuanChuan Industry Co.,Ltd. 50
Changzhou Tianrui Pharmaceutical Technology Co., Ltd. 56
Shanghai DongYang Biotechnology Co., Ltd. 55
Changzhou Anxuan Chemical, Co., Ltd. 58

View Lastest Price from 2-(4-bromo-2-chlorophenyl)acetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(4-bromo-2-chlorophenyl)acetic acid pictures 2019-07-06 2-(4-bromo-2-chlorophenyl)acetic acid
916516-89-7
 $1.00 1kg 99% 200kg Career Henan Chemical Co

2-(4-bromo-2-chlorophenyl)acetic acid Spectrum

2-(4-bromo-2-chlorophenyl)acetic acid(916516-89-7)1HNMR

916516-89-7(2-(4-bromo-2-chlorophenyl)acetic acid)Related Search:

Methyl 2-(4-broMo-2-chlorophenyl)acetate (4-BROMO-2-CHLOROPHENYL)ACETONOTRILE 2-(5-bromo-2-chlorophenyl)acetic acid 2-(2-bromo-6-chlorophenyl)acetic acid 3-bromo-2-chlorophenylacetic acid
2-Chlorophenylacetic acid

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2-(4-bromo-2-chlorophenyl)acetic acid Benzeneacetic acid, 4-broMo-2-chloro- 4-Bromo-2-chlorobenzeneacetic acid 916516-89-7