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4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE

CAS No.
89720-77-4
Chemical Name:
4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE
Synonyms
4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE;Benzene, 4-bromo-1-(bromomethyl)-2-chloro-
CBNumber:
CB52603343
Molecular Formula:
C7H5Br2Cl
Molecular Weight:
284.38
MDL Number:
MFCD15526905
MOL File:
89720-77-4.mol
MSDS File:
SDS
Last updated:2026-05-28 03:30:08
Product description Number Pack Size Price
4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% OR960144 1g $32
4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% OR960144 5g $111
4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% OR960144 10g $184
4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% OR960144 25g $362
4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% OR960144 1g $32
More product size

4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE Properties

storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form liquid
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Health Hazard (GHS08)
GHS05,GHS08
Signal word  Danger
Hazard statements  EUH208-H314-H334
Precautionary statements  P280-P301+P330+P331-P303+P361+P353
RIDADR  3265
HazardClass  8
PackingGroup 
HS Code  2903998090

4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR960144 4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% 89720-77-4 1g $32 2026-06-04 Buy
Apolloscientific OR960144 4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% 89720-77-4 5g $111 2026-06-04 Buy
Apolloscientific OR960144 4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% 89720-77-4 10g $184 2026-06-04 Buy
Apolloscientific OR960144 4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% 89720-77-4 25g $362 2026-06-04 Buy
Apolloscientific OR960144 4-Bromo-1-(bromomethyl)-2-chlorobenzene 95% 89720-77-4 1g $32 2026-06-04 Buy
Product number Packaging Price Buy
OR960144 1g $32 Buy
OR960144 5g $111 Buy
OR960144 10g $184 Buy
OR960144 25g $362 Buy
OR960144 1g $32 Buy

4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE Chemical Properties,Uses,Production

Uses

4-Bromo-1-bromomethyl-2-chlorobenzene is used in the preparation of selective aldose reductase inhibitors.

Synthesis

(4-Bromo-2-chlorophenyl)methanol

185315-48-4

4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE

89720-77-4

To a solution of (4-bromo-2-chlorophenyl)methanol (2.80 g, 12.67 mmol) in dichloromethane (60.0 mL) was added sequentially carbon tetrabromide (4.41 g, 13.30 mmol) and triphenylphosphine (3.48 g, 13.30 mmol) under argon protection and at 0 °C. The reaction mixture was stirred at room temperature for 4 hours. After completion of the reaction, the mixture was concentrated under reduced pressure and the resulting crude product was purified by fast column chromatography (eluent: hexane solution of 10% ethyl acetate) to afford 2-chloro-4-bromobenzyl bromide as a colorless oil (3.59 g, 100% yield).1H NMR (400 MHz, CDCl3): δ 4.53 (s, 2H), 7.29 (d, J = 8.2 Hz. 1H), 7.39 (dd, J = 8.2, 1.9 Hz, 1H), 7.56 (d, J = 1.9 Hz, 1H).

References

[1] Patent: WO2004/74270, 2004, A2. Location in patent: Page 175
[2] Patent: WO2006/18725, 2006, A1. Location in patent: Page/Page column 235-236
[3] Patent: WO2008/18827, 2008, A1. Location in patent: Page/Page column 65-66
[4] Patent: WO2010/15652, 2010, A2. Location in patent: Page/Page column 68
[5] Tetrahedron Letters, 2016, vol. 57, # 3, p. 449 - 451

89794-02-5
89720-77-4
Synthesis of 4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE from 4-BROMO-2-CHLOROTOLUENE
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View Lastest Price from 4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE manufacturers

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4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE pictures 2026-07-09 4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE
89720-77-4
$1.00-101.00 1KG 99% Henan Fengda Chemical Co., Ltd

4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE Spectrum

4-BROMO-1-BROMOMETHYL-2-CHLORO-BENZENE Benzene, 4-bromo-1-(bromomethyl)-2-chloro- 89720-77-4 89720-77-0 Aromatics Intermediates