ChemicalBook >> CAS DataBase List >>4-(4-Trifluoromethylphenoxy)aniline

4-(4-Trifluoromethylphenoxy)aniline

CAS No.
57478-19-0
Chemical Name:
4-(4-Trifluoromethylphenoxy)aniline
Synonyms
4-(4-Trifluoromethylphenoxy)aniline;4-(4-Ttifluoromethylphenoxy)aniline;P-(4-TRIFLUOROMETHYLPHENOXY)-ANILINE;4-[(4-Trifluoromethylphenyl)oxy]aniline;4-(4-trifluoromethylphenoxy)benzeneamine;4-[4-(Trifluoromethyl)phenoxy]benzenamine;Benzenamine, 4-[4-(trifluoromethyl)phenoxy]-;[4-[(4-Trifluoromethylphenyl)oxy]phenyl]amine
CBNumber:
CB2174754
Molecular Formula:
C13H10F3NO
Molecular Weight:
253.22
MDL Number:
MFCD00170930
MOL File:
57478-19-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:24

4-(4-Trifluoromethylphenoxy)aniline Properties

Melting point 70-80℃
Boiling point 326℃
Density 1.293
Flash point 151℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
form solid
pka 4.41±0.10(Predicted)
color Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P305+P351+P338
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36/37/39
HS Code  2922290090

4-(4-Trifluoromethylphenoxy)aniline price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FT105936 4-[4-(trifluoromethyl)phenoxy]aniline 57478-19-0 500mg $900 2026-06-04 Buy
Biosynth FT105936 4-[4-(trifluoromethyl)phenoxy]aniline 57478-19-0 250mg $900 2026-06-04 Buy
Biosynth FT105936 4-[4-(trifluoromethyl)phenoxy]aniline 57478-19-0 1000mg $900 2026-06-04 Buy
Apolloscientific PC48729 4-(4-(Trifluoromethyl)phenoxy)aniline 98% 57478-19-0 1g $145 2026-06-04 Buy
Apolloscientific PC48729 4-(4-(Trifluoromethyl)phenoxy)aniline 98% 57478-19-0 5g $403 2026-06-04 Buy
Product number Packaging Price Buy
FT105936 500mg $900 Buy
FT105936 250mg $900 Buy
FT105936 1000mg $900 Buy
PC48729 1g $145 Buy
PC48729 5g $403 Buy

4-(4-Trifluoromethylphenoxy)aniline Chemical Properties, Uses, Production

Synthesis

4-Bromobenzotrifluoride

402-43-7

4-(4-TRIFLUOROMETHYLPHENOXY)ANILINE

57478-19-0

The general procedure for the synthesis of 4-(4-trifluoromethylphenoxy)aniline from p-bromobenzotrifluoride was as follows: to a stirred solution of 4-bromobenzotrifluoride (11.2 g, 50 mmol) in dimethylsulfoxide (50 mL) was added powdered potassium carbonate (3.4 g, 60 mmol) and 4-aminophenol (6.6 g, 55 mmol) sequentially. The reaction suspension was heated and stirred at 90 °C for 4.5 hours. After completion of the reaction, the mixture was poured into water and extracted with diisopropyl ether. The organic phase was separated, filtered and decanted, and the organic phase was washed with water and subsequently dried over magnesium sulfate. The solvent was evaporated under reduced pressure to give 9.6 g of brown oily crude product. The crude product was ground with pentane, the precipitate was collected by filtration, washed with pentane and dried to give 3.3 g of the target compound 4-(4-trifluoromethylphenoxy)aniline in 27% yield with a melting point of 72 °C.

References

[1] Patent: EP1275301, 2003, A1

4-(4-Trifluoromethylphenoxy)aniline Preparation Products And Raw materials

4-(4-Trifluoromethylphenoxy)aniline Suppliers

Global Suppliers ( 77)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Wuhan Luohua Medical Technology Co.,Ltd. 13477084141; 13477084141 sales@luohuapharm.com China 468 60
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2853 52
Shanghai Run-Biotech Co., Ltd. 021-57171705 13817537615 sales@run-biotech.com China 2278 58
Wuxi Zhangkun Biochemical Technology Co., Ltd. +86 0510-85629785 China 2321 58
Amatek Scientific Co. Ltd. 0512-56316828 4008675858 sales@amateksci.com China 9848 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60

View Latest Price from 4-(4-Trifluoromethylphenoxy)aniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	4-(4-TRIFLUOROMETHYLPHENOXY)ANILINE pictures 2020-01-05 4-(4-TRIFLUOROMETHYLPHENOXY)ANILINE
57478-19-0
$9.80 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co

4-(4-Trifluoromethylphenoxy)aniline Spectrum

4-(4-Ttifluoromethylphenoxy)aniline Benzenamine, 4-[4-(trifluoromethyl)phenoxy]- [4-[(4-Trifluoromethylphenyl)oxy]phenyl]amine 4-[(4-Trifluoromethylphenyl)oxy]aniline P-(4-TRIFLUOROMETHYLPHENOXY)-ANILINE 4-[4-(Trifluoromethyl)phenoxy]benzenamine 4-(4-trifluoromethylphenoxy)benzeneamine 4-(4-Trifluoromethylphenoxy)aniline 57478-19-0