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FLUORODIFEN

FLUORODIFEN structure

CAS No.: 15457-05-3

Chemical Name:: FLUORODIFEN

Synonyms: Flurodifen;Soyex;C 6989;C 6929;Preferan;Preforan;NSC 58415;Fluordifen;FLUORODIFEN;PREFORAN(R)

CBNumber:: CB4754044

Molecular Formula:: C13H7F3N2O5

Molecular Weight:: 328.2

MDL Number:: MFCD00055532

MOL File:: 15457-05-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-31 15:25:13

Product description	Number	Pack Size	Price
Fluorodifen PESTANAL	45506	250mg	$27.1
Fluorodifen	F590968	10mg	$40
Fluorodifen	F590968	25mg	$90
Fluorodifen	450204	10mg	$305
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FLUORODIFEN Properties

Melting point	94℃
Boiling point	371.1±42.0 °C(Predicted)
Density	1.5601 (estimate)
solubility	Chloroform (Slightly), Methanol (Slightly)
color	Yellowish-brown crystals
Water Solubility	2mg/L(20 ºC)
BRN	2018474
Henry's Law Constant	6.5×10² mol/(m³Pa) at 25℃, MacBean (2012)
Major Application	agriculture environmental
InChI	1S/C13H7F3N2O5/c14-13(15,16)8-1-6-12(11(7-8)18(21)22)23-10-4-2-9(3-5-10)17(19)20/h1-7H
InChIKey	HHMCAJWVGYGUEF-UHFFFAOYSA-N
SMILES	[O-][N+](=O)c1ccc(Oc2ccc(cc2[N+]([O-])=O)C(F)(F)F)cc1
FDA UNII	H4154A0WOP
EPA Substance Registry System	Fluorodifen (15457-05-3)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS09
Signal word	Warning
Hazard statements	H319-H332-H400
Precautionary statements	P273-P304+P340+P312-P305+P351+P338
PPE	dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes	Xi,N
Risk Statements	36-50/53
Safety Statements	26-60-61
RIDADR	UN3077 9/PG 3
WGK Germany	2
RTECS	KO2750000
TSCA	TSCA listed
Storage Class	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Inhalation Aquatic Acute 1 Eye Irrit. 2
Toxicity	LD50 orl-rat: 9000 mg/kg FMCHA2 -,C194,83

FLUORODIFEN price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	45506	Fluorodifen PESTANAL	15457-05-3	250mg	$27.1	2025-07-31	Buy
TRC	F590968	Fluorodifen	15457-05-3	10mg	$40	2021-12-16	Buy
TRC	F590968	Fluorodifen	15457-05-3	25mg	$90	2021-12-16	Buy
Usbiological	450204	Fluorodifen	15457-05-3	10mg	$305	2021-12-16	Buy

Product number	Packaging	Price	Buy
45506	250mg	$27.1	Buy
F590968	10mg	$40	Buy
F590968	25mg	$90	Buy
450204	10mg	$305	Buy

FLUORODIFEN Chemical Properties,Uses,Production

Chemical Properties

Yellowish brown crystal. Melting point 93-94 ℃, vapor pressure (20 ℃) is 9.3 × 10-9kPa; solubility (20 ℃), 2ppm in water, acetone 75% (W/V), benzene 52% (W/V), dichloromethane 68% (W/V), isopropanol 12% (W/V).

Uses

Refer to the productμs Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Definition

ChEBI: Fluorodifen is an aromatic ether.

Production Methods

The commercial production of fluorodifen follows a concise two-step nucleophilic aromatic substitution. First, 2-chloro-5-(trifluoromethyl)nitrobenzene is prepared by nitration of 4-chlorobenzotrifluoride with mixed acid, yielding the 2-nitro isomer after steam distillation. This intermediate is then reacted with 4-nitrophenol sodium salt displacing chloride to form the diaryl ether linkage; the mixture is diluted with water, acidified, and the crude product filtered, washed, and recrystallised from ethanol to technical-grade fluorodifen.

Mechanism of action

Inhibits non-cyclic electron transport

Safety Profile

Mildly toxic by ingestion. An eyeirritant. Used as an herbicide. When heated todecomposition it emits very toxic fumes of NOx and Fí.

Metabolic pathway

Photopysis products of eight substituted diphenyl ethers (preforan, nitrofen, MC-338, MC-4379, MC-3761, MC-5127, MC-6063, and MC-7181) irradiated by a Raryonette reactor in solutions of water, cyclohexane, and methanol indicates that the major reaction pathways of these biphenyl ethers include reductive dehalogenation, decarboxyalkylation, reduction of nitro substituents to amines, and cleavage of the ether linkage to yield phenols.

Pesticide Type

Herbicide

FLUORODIFEN Preparation Products And Raw materials

Raw materials

4-Chlorotoluene 4-Chlorobenzotrifluoride

Preparation Products

FLUORODIFEN Suppliers

Global( 64)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53799	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Sichuan Kulinan Technology Co., Ltd	400-1166-196 18981987031	cdhxsj@163.com	China	11674	57
Chengdu Ai Keda Chemical Technology Co., Ltd.	4008-755-333 18080918076	800078821@qq.com	China	9706	55
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Shandong Xiya Chemical Co., Ltd.	4009903999 13395398332	sales@xiyashiji.com	China	20788	60
Shenzhen Regent Biochemical Technology Co., Ltd.	0755-85201366 18938635012	sales@regentsciences.com	China	9375	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226	sales@rrkchem.com	China	57336	58
Shanghai Jiegu Biotechnology Co., Ltd.	021-51698675	sales@jiejiegroup.com	China	8189	58
ShangHai Anpel Co, Ltd.	18502138905	shanpel@anpel.com.cn	China	9604	58

Supplier	Advantage
DAYANG CHEM (HANGZHOU) CO.,LTD	58
J & K SCIENTIFIC LTD.	76
Sichuan Kulinan Technology Co., Ltd	57
Chengdu Ai Keda Chemical Technology Co., Ltd.	55
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shandong Xiya Chemical Co., Ltd.	60
Shenzhen Regent Biochemical Technology Co., Ltd.	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Shanghai Jiegu Biotechnology Co., Ltd.	58
ShangHai Anpel Co, Ltd.	58

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2-NITRO-1-(4-NITROPHENOXY)-4-(TRIFLUOROMETHYL)BENZENE 4-NITROPHENYL A'A'A-TRIFLUORO-2-NITRO-P-TOLYL ETHER C 6989 FLUORODIFEN P-NITROPHENYL-2-NITRO-4-[TRIFLUOROMETHYL] PHENYL ETHER PREFORAN(R) FLUORODIFEN PESTANAL (4-NITROPHENYL-2-NI fluorodifen (bsi,iso,ansi,wssa,jmaf) 2-Nitro-1-(4-nitrophenoxy)-(trifluoromethylbenzene Fluorodifen 1g [15457-05-3] NSC 58415 Fluorodifen 0 2,4’-dinitro-4-trifluoromethyl-diphenylether 2,4'-Dinitro-4-(trifluoromethyl)diphenyl ether 2,4-Dinitro-p-trifluoromethyl phenyl ether 2-nitro-1-(4-nitrophenoxy)-4-(trifluoromethyl)-benzen 4’-trifluoromethyl-2’,4-dinitrodiphenylether 4-Nitrophenyl 2-nitro-4-(trifluoromethyl)phenyl ether 4-Nitrophenyl 4-(trifluoromethyl)-2-nitrophenyl ether 4-Nitrophenyl alpha,alpha,alpha-trifluoro-2-nitro-p-tolyl ether 4-nitrophenyl4-(trifluoromethyl)-2-nitrophenylether 4-nitrophenylalpha,alpha,alpha-trifluoro-2-nitro-p-tolylether 4-Trifluoromethyl-2,4'-dinitrodiphenyl ether 4-Trifluoromethyl-2,4'-dinitrophenyl ether Benzene, 2-nitro-1-(4-nitrophenoxy)-4-(trifluoromethyl)- benzene,2-nitro-1-(4-nitrophenoxy)-4-(trifluoromethyl)- C 6929 Ether, 2,4'-Dinitro-4-trifluoromethyldiphenyl Ether, p-nitrophenyl alpha,alpha,alpha-trifluoro-2-nitro-p-tolyl ether,(p-nitrophenyl)(alpha,alpha,alpha-trifluoro-2-nitro-p-tolyl) ether,p-nitrophenylα,α,α-trifluoro-2-nitro-p-tolyl Fluordifen Fluoridifene fluorodifene Fluorodiphen p-Nitrophenyl alpha,alpha,alpha-trifluoro-2-nitro-p-tolyl ether p-nitrophenylalpha,alpha,alpha-trifluoro-2-nitro-p-tolylether Preferan Preforan Soyex Flurodifen@100 μg/mL in Methanol Flurodifen@1000 μg/mL in Methanol Fluorodifen in Acetone C13790000 Fluorodifen Fluorodifen 100 μg/ml Ethyl acetate Fluorodifen in Acetonitrile Bifenazate Impurity 9 Flurodifen 15457-05-3 C13H7F3N2O5 Alpha sort Diphenyl etherPesticides&Metabolites E-GAlphabetic F FA - FL Herbicides Pesticides&Metabolites