DL-Histidine
- CAS No.
- 4998-57-6
- Chemical Name:
- DL-Histidine
- Synonyms
- HISTIDINE;free base;H-DL-HIS-OH;DL-HIS;DL-His-OH;DL-Histdine;DL-Histidin;DL-HISTIDINE;DL-Histidine 0;HISTIDINE, DL-
- CBNumber:
- CB2177472
- Molecular Formula:
- C6H9N3O2
- Molecular Weight:
- 155.15
- MDL Number:
- MFCD00005208
- MOL File:
- 4998-57-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 273 °C (dec.)(lit.) |
|---|---|
| Boiling point | 278.95°C (rough estimate) |
| Density | 1.3092 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | 0.5 M HCl: soluble |
| form | powder to crystal |
| pka | 1.8(at 25℃) |
| color | White to Almost white |
| Merck | 14,4720 |
| BRN | 7800 |
| Major Application | peptide synthesis |
| Cosmetic Ingredient Review (CIR) | DL-Histidine (4998-57-6) |
| InChI | 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11) |
| InChIKey | HNDVDQJCIGZPNO-UHFFFAOYSA-N |
| SMILES | NC(Cc1c[nH]cn1)C(O)=O |
| CAS DataBase Reference | 4998-57-6(CAS DataBase Reference) |
| FDA 21 CFR | 310.545; 582.5361 |
| EWG's Food Scores | 1 |
| FDA UNII | QU6SDF3Q03 |
| EPA Substance Registry System | Histidine (4998-57-6) |
| UNSPSC Code | 12352209 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 22-24/25-36/37-26 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
DL-Histidine price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H7750 | DL-Histidine ≥99% (TLC) | 4998-57-6 | 25g | $382 | 2026-04-30 | Buy |
| Sigma-Aldrich | H7750 | DL-Histidine ≥99% (TLC) | 4998-57-6 | 100g | $406 | 2025-07-31 | Buy |
| TCI Chemical | H0148 | DL-Histidine >98.0%(HPLC)(T) | 4998-57-6 | 1g | $20 | 2026-04-30 | Buy |
| TCI Chemical | H0148 | DL-Histidine >98.0%(HPLC)(T) | 4998-57-6 | 25g | $142 | 2026-04-30 | Buy |
| Usbiological | H5100-15 | DL-Histidine, 99% ≥99% | 4998-57-6 | 100g | $269 | 2026-06-03 | Buy |
DL-Histidine Chemical Properties, Uses, Production
Chemical Properties
white to slightly yellow crystalline powder
Uses
histidine is a skin-conditioning amino acid.
Uses
DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).
Definition
ChEBI: An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.
Synthesis Reference(s)
Journal of the American Chemical Society, 67, p. 502, 1945 DOI: 10.1021/ja01219a513
Chemical and Pharmaceutical Bulletin, 35, p. 3447, 1987
Biochem/physiol Actions
L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.
DL-Histidine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from DL-Histidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | DL-Histidine
4998-57-6
|
1KG | 98.0%-101.0% | 10 TONS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-08 | BACE-IN-1 acetate | $89.00-298.00 | 99.71% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-13 | LTX315 acetate | 99.93% | 10g | TargetMol Chemicals Inc. |
-
- DL-Histidine
4998-57-6
- 98.0%-101.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- BACE-IN-1 acetate
- $89.00-298.00
- 99.71%
- TargetMol Chemicals Inc.
-
- LTX315 acetate
- $0.00
- 99.93%
- TargetMol Chemicals Inc.
