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DL-Pyroglutamic acid

CAS No.
149-87-1
Chemical Name:
DL-Pyroglutamic acid
Synonyms
2-PYRROLIDONE-5-CARBOXYLIC ACID;H-DL-PYR-OH;DL-Pyr-OH;5-OXO-DL-PROLINE;DL-Proline, 5-oxo-;DL-PYR;DL- pGlu-OH;DL-5-Oxoproline;DL-Pyroglutamic;DL- pyroglutaMate
CBNumber:
CB2709505
Molecular Formula:
C5H7NO3
Molecular Weight:
129.11
MDL Number:
MFCD00064322
MOL File:
149-87-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

DL-Pyroglutamic acid Properties

Melting point 183-185 °C(lit.)
Boiling point 239.15°C (rough estimate)
Density 1.3816 (rough estimate)
vapor pressure 0Pa at 25℃
refractive index 1.4220 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility 52g/l
pka 3.48±0.20(Predicted)
form Crystalline Powder
color White
PH 1.7 (50g/l, H2O, 20℃)
Water Solubility 5.67 g/100 mL (20 ºC)
BRN 82131
Major Application peptide synthesis
InChI 1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)
InChIKey ODHCTXKNWHHXJC-UHFFFAOYSA-N
SMILES OC(=O)C1CCC(=O)N1
LogP 0.065 at 21.1℃
CAS DataBase Reference 149-87-1(CAS DataBase Reference)
FDA UNII 6VT1YZM21H
NIST Chemistry Reference DL-5-Oxoproline(149-87-1)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Warning
Hazard statements  H318-H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P280a-P304+P340-P405-P501a
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29337900
Storage Class 11 - Combustible Solids
REACH Registrations Active
NFPA 704
1
3 0

DL-Pyroglutamic acid price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 292915 2-Pyrrolidone-5-carboxylic acid 99% 149-87-1 5g $38.2 2026-04-30 Buy
Sigma-Aldrich 292915 2-Pyrrolidone-5-carboxylic acid 99% 149-87-1 100g $124 2026-04-30 Buy
TCI Chemical G0061 DL-Pyroglutamic Acid >99.0%(T) 149-87-1 25g $28 2026-04-30 Buy
TCI Chemical G0061 DL-Pyroglutamic Acid >99.0%(T) 149-87-1 100g $61 2026-04-30 Buy
Cayman Chemical 36375 DL-Pyroglutamic Acid ≥95% 149-87-1 50g $29 2026-04-30 Buy
Product number Packaging Price Buy
292915 5g $38.2 Buy
292915 100g $124 Buy
G0061 25g $28 Buy
G0061 100g $61 Buy
36375 50g $29 Buy

DL-Pyroglutamic acid Chemical Properties, Uses, Production

Chemical Properties

DL-Pyroglutamic acid is white crystalline powder

Uses

DL-Pyroglutamic acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.

Uses

DL-2-Pyrrolidone-5-carboxylic Acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.

Definition

ChEBI: An oxoproline having the oxo group placed at the 5-position. It is an intermediate metabolite in the glutathione cycle.

Flammability and Explosibility

Non flammable

reaction suitability

reaction type: solution phase peptide synthesis

56-86-0
149-87-1
Synthesis of DL-Pyroglutamic acid from L-Glutamic acid
Global Suppliers ( 441)
Supplier Tel Email Country ProdList Advantage
Hubei Hengluyuan Technology co.ltd 027-88188016 18717196322 1764683941@qq.com China 5944 58
Sichuan Tongsheng Amino acids Co.,Ltd. 0838-2274206 17340404235 sales@biots.cn China 300 66
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2202 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66

View Latest Price from DL-Pyroglutamic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DL-Pyroglutamic acid pictures 2026-09-17 DL-Pyroglutamic acid
149-87-1
$800.00-999.00 1kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
DL-Pyroglutamic acid pictures 2026-09-17 DL-Pyroglutamic acid
149-87-1
1KG 98%min 500kgs WUHAN FORTUNA CHEMICAL CO., LTD
DL-Pyroglutamic acid pictures 2026-07-27 DL-Pyroglutamic acid
149-87-1
$29.00 99.88% 10g TargetMol Chemicals Inc.
(+/-)-2-PYRROLIDONE-5-CARBOXYLIC ACID (+/-)-2-PYRROLIDINONE-5-CARBOXYLIC ACID DL-A-PYROGLUTAMIC ACID DL-GLUTAMIC ACID LACTAM DL-PYROGLUTAMIC ACID DL-2-PYRROLIDINONE-5-CARBOXYLIC ACID 2-Pyrrolidone-5-carboxylic acid 99% DL- pyroglutaMate (^+)-2-Pyrrolidinone-5-carboxylicacid,99% DL-PYR DL-Pyr-OH DL-2-Pyrrolidone-5-carboxylic acid for synthesis Pyroglutamic acid, 98.5% D,L-2-PYRROLIDONE-5-CARBOXYLIC ACID DL-5-OXO-2-PYRROLIDINECARBOXYLIC ACID DL-5-PYRROLIDONE-2-CARBOXYLIC ACID LABOTEST-BB LT00005913 DL-5-Oxoproline DL-Pyroglutamic (n)-2-pyrrolidinone-5-carboxylic acid DL- pGlu-OH Pyroglutamic acid and esters (±)-2-Pyrrolidone-5-carboxylic acid, DL-5-Oxo-2-pyrrolidinecarboxylic acid DL-5-Oxo-2-pyrrolidinecarboxylic acid, DL-Pyroglutamic acid DL-Pyroglutamic acid ,98.5% D,l-2-pyrrolidone-5-carboxylic acid,98% dl-Pyrrolidone carboxylic acid DL-Glutamic Acid Lactam 2-Pyrrolidone-5-carboxylic Acid DL-PyroglutamicAcid> DL-Pyroglutamic acid USP/EP/BP C5H7NO3 DL-Pyroglutamic acid 149-87-1 DL-Pyroglutamic Acid, ≥ 99.0% Carboglutamate impurity 6 DL-Pyroglutamic acid, 10 mM in DMSO DL-2-Pyrrolidone-5-carboxylic acidCNA10145-25g 2-PYRROLIDONE-5-CARBOXYLIC ACID 5-OXO-DL-PROLINE DL-Proline, 5-oxo- H-DL-PYR-OH (+/-)-2-PYRROLIDINONE-5-CARBOXYLICACID (+/-)-2-PYRROLIDONE-5-CARBOXYLICACID DL-GLUTAMICACIDChemicalbookLACTAM 149-87-1 CARBOXYLIC ACID Others Peptide Synthesis Pyroglutamine Derivatives Specialty Synthesis Unnatural Amino Acid Derivatives Pyrrole&Pyrrolidine&Pyrroline Organic acids Pyroglutamic acid [Pyr, pGu] Amino Acids Biochemistry Biological-modified Amino Acids Amino Acids Heterocycles Amino acid