DL-Pyroglutamic acid
- CAS No.
- 149-87-1
- Chemical Name:
- DL-Pyroglutamic acid
- Synonyms
- 2-PYRROLIDONE-5-CARBOXYLIC ACID;H-DL-PYR-OH;DL-Pyr-OH;5-OXO-DL-PROLINE;DL-Proline, 5-oxo-;DL-PYR;DL- pGlu-OH;DL-5-Oxoproline;DL-Pyroglutamic;DL- pyroglutaMate
- CBNumber:
- CB2709505
- Molecular Formula:
- C5H7NO3
- Molecular Weight:
- 129.11
- MDL Number:
- MFCD00064322
- MOL File:
- 149-87-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 183-185 °C(lit.) |
|---|---|
| Boiling point | 239.15°C (rough estimate) |
| Density | 1.3816 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.4220 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | 52g/l |
| pka | 3.48±0.20(Predicted) |
| form | Crystalline Powder |
| color | White |
| PH | 1.7 (50g/l, H2O, 20℃) |
| Water Solubility | 5.67 g/100 mL (20 ºC) |
| BRN | 82131 |
| Major Application | peptide synthesis |
| InChI | 1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9) |
| InChIKey | ODHCTXKNWHHXJC-UHFFFAOYSA-N |
| SMILES | OC(=O)C1CCC(=O)N1 |
| LogP | 0.065 at 21.1℃ |
| CAS DataBase Reference | 149-87-1(CAS DataBase Reference) |
| FDA UNII | 6VT1YZM21H |
| NIST Chemistry Reference | DL-5-Oxoproline(149-87-1) |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H318-H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P280a-P304+P340-P405-P501a | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29337900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
DL-Pyroglutamic acid price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 292915 | 2-Pyrrolidone-5-carboxylic acid 99% | 149-87-1 | 5g | $38.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | 292915 | 2-Pyrrolidone-5-carboxylic acid 99% | 149-87-1 | 100g | $124 | 2026-04-30 | Buy |
| TCI Chemical | G0061 | DL-Pyroglutamic Acid >99.0%(T) | 149-87-1 | 25g | $28 | 2026-04-30 | Buy |
| TCI Chemical | G0061 | DL-Pyroglutamic Acid >99.0%(T) | 149-87-1 | 100g | $61 | 2026-04-30 | Buy |
| Cayman Chemical | 36375 | DL-Pyroglutamic Acid ≥95% | 149-87-1 | 50g | $29 | 2026-04-30 | Buy |
DL-Pyroglutamic acid Chemical Properties, Uses, Production
Chemical Properties
DL-Pyroglutamic acid is white crystalline powder
Uses
DL-Pyroglutamic acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.
Uses
DL-2-Pyrrolidone-5-carboxylic Acid is used in the preparation of AZT steroid conjugates as potent anti-HIV agents.
Definition
ChEBI: An oxoproline having the oxo group placed at the 5-position. It is an intermediate metabolite in the glutathione cycle.
Flammability and Explosibility
Non flammable
reaction suitability
reaction type: solution phase peptide synthesis
DL-Pyroglutamic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Hengluyuan Technology co.ltd | 027-88188016 18717196322 | 1764683941@qq.com | China | 5944 | 58 |
| Sichuan Tongsheng Amino acids Co.,Ltd. | 0838-2274206 17340404235 | sales@biots.cn | China | 300 | 66 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Latest Price from DL-Pyroglutamic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-09-17 | DL-Pyroglutamic acid
149-87-1
|
$800.00-999.00 | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
![]() |
2026-09-17 | DL-Pyroglutamic acid
149-87-1
|
1KG | 98%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | ||
![]() |
2026-07-27 | DL-Pyroglutamic acid
149-87-1
|
$29.00 | 99.88% | 10g | TargetMol Chemicals Inc. |
-

- DL-Pyroglutamic acid
149-87-1
- $800.00-999.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-

- DL-Pyroglutamic acid
149-87-1
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- DL-Pyroglutamic acid
149-87-1
- $29.00
- 99.88%
- TargetMol Chemicals Inc.








