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Amino Tadalafil

Amino Tadalafil structure

CAS No.: 385769-84-6

Chemical Name:: Amino Tadalafil

Synonyms: Amino Tadanafil;Amino Tadalafil;Amino tildenafil;Tildenafil Impurity 18;Amino Tadalafil USP/EP/BP;Aminotadalafil in Methanol;Amino Tadalafil (Standard);Tadalafil N-Desmethyl N-Amino;Amino Tadalafil, 10 mM in DMSO;Tadalafil N-Desmethyl N-Amino Impurity

CBNumber:: CB21872910

Molecular Formula:: C21H18N4O4

Molecular Weight:: 390.39

MDL Number:

MOL File:: 385769-84-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-08-20 20:20:01

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Amino Tadalafil Properties

Melting point	280-282°C
Boiling point	678.9±65.0 °C(Predicted)
Density	1.60±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	16.70±0.40(Predicted)
color	White to Off-White
InChI	InChI=1S/C21H18N4O4/c22-24-9-18(26)25-15(21(24)27)8-13-12-3-1-2-4-14(12)23-19(13)20(25)11-5-6-16-17(7-11)29-10-28-16/h1-7,15,20,23H,8-10,22H2/t15-,20-/m1/s1
InChIKey	VUKJGAVIWMPOOJ-FOIQADDNSA-N
SMILES	N1C2=C(C=CC=C2)C2C[C@]3([H])C(=O)N(N)CC(=O)N3[C@H](C3=CC=C4OCOC4=C3)C1=2
CAS DataBase Reference	385769-84-6
FDA UNII	FY501QO030

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
Safety Statements	24/25
HS Code	29339900

Amino Tadalafil price More Price(54)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	20876	Amino Tadalafil ≥98%	385769-84-6	5mg	$70	2026-04-30	Buy
Cayman Chemical	20876	Amino Tadalafil ≥98%	385769-84-6	10mg	$129	2026-04-30	Buy
Cayman Chemical	20876	Amino Tadalafil ≥98%	385769-84-6	50mg	$369	2026-04-30	Buy
Cayman Chemical	20876	Amino Tadalafil ≥98%	385769-84-6	100mg	$602	2026-04-30	Buy
Usbiological	002553	Amino Tadalafil	385769-84-6	5mg	$418	2026-06-03	Buy

Product number	Packaging	Price	Buy
20876	5mg	$70	Buy
20876	10mg	$129	Buy
20876	50mg	$369	Buy
20876	100mg	$602	Buy
002553	5mg	$418	Buy

Amino Tadalafil Chemical Properties, Uses, Production

Description

Amino tadalafil is an analog of tadalafil , a potent inhibitor of phosphodiesterase 5 with applications in several conditions, including erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction. Amino tadalafil has been detected as an illegal adulterant in a dietary supplement marketed for “tonic effect.”

Chemical Properties

White Solid

Uses

Amino Tadalafil is a drug analog of Tadalafil that used to treatment of male erectile dysfunction drugs.

Mechanism of action

Amino tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5).PDE5, an enzyme found primarily in the smooth muscle of the corpus cavernosum, selectively cleaves and degrades cGMP to 5′-GMP. PDE5 inhibitors are similar in structure to cGMP and they competitively bind to PDE5 and inhibit cGMP hydrolysis, thus enhancing the effects of NO, resulting in prolonging an erection.

in vitro

amino-tadalafil is a structural analogue of tadalafil, the active pharmaceutical ingredient in cialis, a prescription drug approved in the us for treatment of erectile dysfunction (ed). similarly, there have also been reports of herbal or dietary supplements being adulterated with designer ed analogues such as amino-tadalafil [1].

in vivo

in rats treated with both melatonin and tadalafil, the recoveries were more pronounced than in rats given either melatonin or tadalafil alone. the icp/mean arterial pressure value in vehicle-treated rats was significantly higher than in the control group, while in the tadalafil- and tadalafil + melatonin-treated groups have returned this value had returned to control levels. in addition, as an individual treatment, and especially when combined with tadalafil, melatonin prevented spinal cord injury (sci)-induced oxidative damage to cavernosal tissues and restored ed, most likely due to its anti-oxidant effects [2].

References

[1] hadwiger me, trehy ml, ye w, moore t, allgire j, westenberger b. identification of amino-tadalafil and rimonabant in electronic cigarette products using high pressure liquid chromatography with diode array and tandem mass spectrometric detection. j chromatogr a. 2010 nov 26;1217(48):7547-55.
[2] tavuk u hh, sener te, tinay i, akbal c, er ahin m, cevik o, cadirci s, reiter rj, sener g. melatonin and tadalafil treatment improves erectile dysfunction after spinal cord injury in rats. clin exp pharmacol physiol. 2014 apr;41(4):309-16.

Amino Tadalafil Preparation Products And Raw materials

Raw materials

Preparation Products

Amino Tadalafil Suppliers

Global Suppliers ( 177)

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Haiyue Biotechnology Co., Ltd	15926453367	haiyue1682022@163.com	China	251	58
Guangzhou Xucheng Biotechnology Co., Ltd	16539527651	2432687429@qq.com	China	28	58
LangFangshi Zekang Pharma Tech CO.,Itd.	0316-2883536 19333636468	93618484@qq.com	China	2824	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
China Nobel Chem Co., Limited	+86(0)21 60484900		China	762	50
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18188	56
Finetech Industry Limited	027-87465837 19945049750	sales@finetechnology-ind.com	China	9331	58
DONGGUAN AOME BIOTECHNOLOGY CO.,LTD	13790132747	2784729268@qq.com	China	49	50
Shanghai HuanChuan Industry Co.,Ltd.	021-61478794	sales@hcshhai.com	China	9781	50

Supplier	Advantage
Hubei Haiyue Biotechnology Co., Ltd	58
Guangzhou Xucheng Biotechnology Co., Ltd	58
LangFangshi Zekang Pharma Tech CO.,Itd.	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
China Nobel Chem Co., Limited	50
Quality Control Solutions Ltd.	56
Finetech Industry Limited	58
DONGGUAN AOME BIOTECHNOLOGY CO.,LTD	50
Shanghai HuanChuan Industry Co.,Ltd.	50

View Latest Price from Amino Tadalafil manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-18	Amino Tadalafil 385769-84-6		1KG	98%	2000	Shenzhen Nexcon Pharmatechs Ltd.
2026-09-18	Amino Tadalafil 385769-84-6	$10.00	1ASSAYS	99%	1 ton	RongNa Biotechnology Co.,Ltd
2026-08-27	Amino Tadalafil 385769-84-6		1kg	99%min	1000	LIDE PHARMACEUTICALS LIMITED

Amino Tadalafil
385769-84-6
98%
Shenzhen Nexcon Pharmatechs Ltd.

Amino Tadalafil
385769-84-6
$10.00
99%
RongNa Biotechnology Co.,Ltd

Amino Tadalafil
385769-84-6
$0.00
99%min
LIDE PHARMACEUTICALS LIMITED

Amino Tadalafil Spectrum

Amino Tadalafil(385769-84-6)¹HNMR

385769-84-6 (Amino Tadalafil) Related Search:

(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester D(+)-Tryptophan Tadalafil iMpurity B Tadalafil KetolactaM (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester

(1R,3R)-2-acetyl-1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indole-3-carboxylate 1,1'-Ethylidenebis(tryptophan) (1S,3R)-1-Benzo[1,3]dioxol-5-yl-2-(2-chloro-acetyl)-2,3,4,9-tetrahydro-1H-b-carboline-3-carboxylic Acid Methyl Ester N-Octyl Nortadalafil Tadalafil EP Impurity

2-Hydroxypropyl Nortadalafil (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester Vardenafil hydrochloride Carteolol hydrochloride Tadalafil

vardenafil tadalafi Trimethylsulfoxonium bromide

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Amino Tadalafil (6R,12aR)-2-Amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Amino Tadalafil (6R,12Ar)-2-Amino-6-(1,3-Benzodioxol-5-Yl)-2,3,6,7,12,12A-Hexahydropyrazino[1',2':1,6]Pyrido[3,4-B]Indole-1,4-Dione (6R,12aR)-2-Amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-1,4-dione (6R,12aR)-2-amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione Best Male Enhancement Drugs 99% Amino Tadalafil powder China manufacturer Tadalafil N-Desmethyl N-Amino Impurity Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 2-amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-, (6R,12aR)- Amino Tadalafil solution in Methanol, 100μg/mL Amino Tadalafil USP/EP/BP (6R,12aR)-2-amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-he... Tadalafil N-Desmethyl N-Amino Amino tildenafil (6R,12aR)-2-Amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione,2-amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-, (6R,12aR)- Aminotadalafil in Methanol Tildenafil Impurity 18 Amino Tadalafil, 10 mM in DMSO (6R,12aR)-2-Amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione Amino Tadalafil (Standard) Amino Tadanafil 385769-84-6 Drug Analogues Intermediates & Fine Chemicals Pharmaceuticals