(4-Methoxy-benzoylamino)-acetic acid
- CAS No.
- 13214-64-7
- Chemical Name:
- (4-Methoxy-benzoylamino)-acetic acid
- Synonyms
- IFLAB-BB F1130-0072;4-Methoxyhippuric acid;p-Methoxyhippuric acid;(4-methoxybenzoyl)glycine;N-(4-Methoxybenzoyl)glycine;4-methyoxybenzoyl-N-glycine;Glycine, N-(4-methoxybenzoyl)-;2-(4-MethoxybenzaMido)acetic acid;(4-Methoxy-benzoylamino)-acetic acid;2-[(4-METHOXYPHENYL)FORMAMIDO]ACETATE
- CBNumber:
- CB2202945
- Molecular Formula:
- C10H11NO4
- Molecular Weight:
- 209.2
- MDL Number:
- MFCD00181815
- MOL File:
- 13214-64-7.mol
- MSDS File:
- SDS
| Melting point | 155-158° |
|---|---|
| Boiling point | 463.7±30.0 °C(Predicted) |
| Density | 1.268±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.53±0.10(Predicted) |
| Appearance | White to off-white Solid |
| FDA UNII | XVG357K99P |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HazardClass | IRRITANT |
(4-Methoxy-benzoylamino)-acetic acid price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS39204 | 2-(4-Methoxybenzamido)acetic acid 97% | 13214-64-7 | 1g | $64 | 2026-06-04 | Buy |
| Activate Scientific | AS39204 | 2-(4-Methoxybenzamido)acetic acid 97% | 13214-64-7 | 5g | $128 | 2026-06-04 | Buy |
| Matrix Scientific | 044057 | 2-[(4-Methoxybenzoyl)amino]acetic acid | 13214-64-7 | 1.00g | $52 | 2026-05-18 | Buy |
| Matrix Scientific | 044057 | 2-[(4-Methoxybenzoyl)amino]acetic acid | 13214-64-7 | 5.00g | $106 | 2026-05-18 | Buy |
| Matrix Scientific | 044057 | 2-[(4-Methoxybenzoyl)amino]acetic acid | 13214-64-7 | 10.00g | $194 | 2026-05-18 | Buy |
(4-Methoxy-benzoylamino)-acetic acid Chemical Properties,Uses,Production
Definition
ChEBI: 2-[(4-methoxyphenyl)formamido]acetic acid is a N-acylglycine. It is functionally related to a N-benzoylglycine.
Synthesis
![ETHYL 2-[(4-METHOXYBENZOYL)AMINO]ACETATE](/CAS/GIF/51220-57-6.gif)
51220-57-6
13214-64-7
General procedure for the synthesis of 2-(4-methoxybenzoylamino)acetic acid from compound (CAS:51220-57-6): the synthesis of compound g was carried out when R1 was methoxyphenyl. The procedure was as follows: 4-methoxybenzoic acid a (2.00 g, 13.80 mmol) was added to a 200 mL round-bottomed flask with 60 mL of dichloromethane (DCM), followed by the sequential addition of EDCI (13.80 mmol), HOBt (13.80 mmol), compound b (15.77 mmol), and triethylamine (Et3N 45.99 mmol). The reaction mixture was stirred at room temperature overnight. After completion of the reaction, it was washed sequentially with water, saturated ammonium chloride solution and saturated brine and the organic phase was dried with anhydrous sodium sulfate. Purification by column chromatography with an eluent ratio of petroleum ether:ethyl acetate = 5:1 to 2:1 afforded compound c (1.80 g, 62.7% yield). Subsequently, compound c was added directly to a mixture containing 45 mL of methanol and 45 mL of aqueous sodium hydroxide (15.19 mmol) and heated to reflux for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and the solvent was evaporated. After adding a small amount of water, the mixture was transferred to a beaker and the pH was adjusted to 1-2 with concentrated hydrochloric acid. extracted with ethyl acetate (EA), the organic phase was washed with saturated brine and dried over anhydrous sodium sulfate. After filtration, the solvent was evaporated to give a white solid d (1.22 g, 76.5% yield).
References
[1] Organic Letters, 2016, vol. 18, # 4, p. 696 - 699
[2] Patent: CN107216282, 2017, A. Location in patent: Paragraph 0060; 0061; 0062; 0063; 0064
(4-Methoxy-benzoylamino)-acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(4-Methoxy-benzoylamino)-acetic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Emeishan Hongsen Biopharmaceutical Co., Ltd. | 0833-6186278 19162541913 | sales@hongshengpharm.com | China | 99 | 60 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Aspire Biological Technology Co., Ltd. | 021-61317773 | sales@aspirebio.com | China | 2880 | 58 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
View Lastest Price from (4-Methoxy-benzoylamino)-acetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-19 | (4-METHOXY-BENZOYLAMINO)-ACETIC ACID
13214-64-7
|
1kg | 99% | 1000kg | Shanghai Joiny Pharmaceutical Co.,LTD |
-
- (4-METHOXY-BENZOYLAMINO)-ACETIC ACID
13214-64-7
- $0.00
- 99%
- Shanghai Joiny Pharmaceutical Co.,LTD
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