Clothianidin
- CAS No.
- 210880-92-5
- Chemical Name:
- Clothianidin
- Synonyms
- Clothianidi;clothianidine;Chlothianidin;Clothianidin TC;3-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-1-nitro-guanidine;Apacz;Belay;Celero;Pancho;Clutch
- CBNumber:
- CB2206079
- Molecular Formula:
- C6H8ClN5O2S
- Molecular Weight:
- 249.67
- MDL Number:
- MFCD06200753
- MOL File:
- 210880-92-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Clothianidin certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | 68965 | 50 mg | $239 |
| Clothianidin PESTANAL | 33589 | 100mg | $222 |
| Clothianidin | C3746 | 250MG | $107 |
| Clothianidin | C3746 | 1G | $267 |
| Clothianidin ≥98% | 29605 | 50mg | $63 |
| More product size | |||
| Melting point | 178.8 °C |
|---|---|
| Boiling point | 412.5±55.0 °C(Predicted) |
| Density | 1.61 |
| vapor pressure | 0Pa at 25℃ |
| storage temp. | 0-6°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml |
| form | Solid |
| pka | 2.76±0.50(Predicted) |
| color | Off-white to light yellow |
| Water Solubility | 327 mg/L at 20 ºC |
| Henry's Law Constant | 3.4×1010 mol/(m3Pa) at 25℃, MacBean (2012) |
| Major Application |
agriculture environmental |
| InChI | 1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11) |
| InChIKey | PGOOBECODWQEAB-UHFFFAOYSA-N |
| SMILES | CN\C(NCc1cnc(Cl)s1)=N/[N+]([O-])=O |
| LogP | 0.7 at 25℃ |
| CAS DataBase Reference | 210880-92-5 |
| FDA UNII | 2V9906ABKQ |
| EPA Substance Registry System | Clothianidin (210880-92-5) |
| Pesticides Freedom of Information Act (FOIA) | Clothianidin |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H410 |
| Precautionary statements | P273-P301+P312+P330 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50/53 |
| Safety Statements | 46-60-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 1 |
| RTECS | ME9565000 |
| HS Code | 29341000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 |
| Hazardous Substances Data | 210880-92-5(Hazardous Substances Data) |
| Toxicity | LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 in rats (mg/l): >6.1 inhalation; LC50 in bobwhite quail, mallard duck (ppm): >5200, >5200 (dietary); LC50 (96 hr) in rainbow trout, bluegill (mg/l): >100, >120 (Ohkawara) |
| REACH Registrations | Active |
Clothianidin price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 68965 | Clothianidin certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland | 210880-92-5 | 50 mg | $239 | 2026-04-30 | Buy |
| Sigma-Aldrich | 33589 | Clothianidin PESTANAL | 210880-92-5 | 100mg | $222 | 2026-04-30 | Buy |
| TCI Chemical | C3746 | Clothianidin | 210880-92-5 | 250MG | $107 | 2026-04-30 | Buy |
| TCI Chemical | C3746 | Clothianidin | 210880-92-5 | 1G | $267 | 2026-04-30 | Buy |
| Cayman Chemical | 29605 | Clothianidin ≥98% | 210880-92-5 | 50mg | $63 | 2026-04-30 | Buy |
Clothianidin Chemical Properties,Uses,Production
Description
Clothianidin is an insecticide for the control of sucking and chewing pests. It is moderately soluble and volatile but has a high potential for leaching to groundwater. It is very persistent in soil and water. Risk of bioaccumulation is low and its acute toxicity to mammals is considered moderate. It is, however, a neurotoxicant. It is toxic to some aquatic organisms but not greatly so to fish. It is highly toxic to honeybees but low risk to earthworms.
Uses
Insecticide.
Production Methods
The commercial production of clothianidin involves a multi-step chemical synthesis process designed for efficiency and scalability. It begins with a condensation reaction between 2-chloro-5-chloromethylthiazole and 1,5-dimethyl-2-nitroimino-hexahydro-1,3,5-triazine in an aqueous solution of tetraalkyl ammonium hydroxide, with potassium carbonate as a base. This reaction yields an intermediate compound, which is then subjected to hydrolysis in an alkylamine solution. The resulting product is purified through filtration, desolvation, extraction, and concentration steps to obtain clothianidin in its final form.
Definition
ChEBI: (E)-clothianidin is a clothiadin that has E configuration at the C=N bond of the nitroguanidine moiety. It has a role as a neonicotinoid insectide.
Flammability and Explosibility
Not classified
Mechanism of action
Translaminar and root systemic activity. Nicotinic acetylcholine receptor (nAChR) channel blocker.
Pesticide Type
Insecticide; Metabolite
Clothianidin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8737 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177 | faithe@yan-xi.com | China | 5838 | 58 |
| Qingdao Trust Agri Chemical Co.,Ltd | +86-008615963231493 +86-008613573296305 | trustagri@hotmail.com | China | 298 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
| Linyi Changqing Chemical Co., LTD | +86-0532-55729510 +86-15853232676 | marketing@echemi.com | China | 287 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
View Lastest Price from Clothianidin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-14 | Clothianidin
210880-92-5
|
1kg | 98 | 200000 | Qingdao Trust Agri Chemical Co.,Ltd | ||
 |
2026-06-02 | Clothianidin
210880-92-5
|
$39.00-92.00 | 99.87% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | Clothianidin
210880-92-5
|
$8.90 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Clothianidin
210880-92-5
- $0.00
- 98
- Qingdao Trust Agri Chemical Co.,Ltd
-
- Clothianidin
210880-92-5
- $39.00-92.00
- 99.87%
- TargetMol Chemicals Inc.
-
- Clothianidin
210880-92-5
- $8.90
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
