3-Methyl-2-oxovaleric acid
- CAS No.
- 1460-34-0
- Chemical Name:
- 3-Methyl-2-oxovaleric acid
- Synonyms
- 3-METHYL-2-OXOPENTANOIC ACID;α-Keto-β-methylvaleric acid;2-KETO-3-METHYLVALERIC ACID;Pentanoic acid, 3-methyl-2-oxo-;3-METHYL-2-OXOVALERIC;METHYLETHYLPYRUVIC ACID;3-methyl-2-oxovalericaci;2-Oxo-3-methylvaleric acid;3-Methyl-2-oxovaleric acid;α-Keto-3-methylvaleric acid
- CBNumber:
- CB2218546
- Molecular Formula:
- C6H10O3
- Molecular Weight:
- 130.14
- MDL Number:
- MFCD00002582
- MOL File:
- 1460-34-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 42°C |
|---|---|
| Boiling point | 84 °C / 18mmHg |
| Density | 1.087±0.06 g/cm3(Predicted) |
| FEMA | 3870 | 3-METHYL-2-OXOPENTANOIC ACID |
| storage temp. | Refrigerator |
| solubility | DMSO : 130 mg/mL (998.92 mM) |
| form | powder to crystal |
| pka | 2.65±0.54(Predicted) |
| color | White to Light yellow |
| JECFA Number | 632 |
| InChI | 1S/C6H10O3/c1-3-4(2)5(7)6(8)9/h4H,3H2,1-2H3,(H,8,9) |
| InChIKey | JVQYSWDUAOAHFM-UHFFFAOYSA-N |
| SMILES | CC(C(C(O)=O)=O)CC |
| LogP | 0.17 |
| Substances Added to Food (formerly EAFUS) | 3-METHYL-2-OXOPENTANOIC ACID |
| CAS DataBase Reference | 1460-34-0(CAS DataBase Reference) |
| FDA UNII | 787T50HCIV |
| UNSPSC Code | 12352106 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36 | |||||||||
| Safety Statements | 26-36/37/39-36 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 2918300090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| NFPA 704 |
|
3-Methyl-2-oxovaleric acid price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS000039 | 3-Methyl-2-oxopentanoic acid AldrichCPR | 1460-34-0 | 50MG | $70.4 | 2026-04-30 | Buy |
| TCI Chemical | K0020 | 3-Methyl-2-oxovaleric Acid >95.0%(GC)(T) | 1460-34-0 | 1g | $200 | 2026-04-30 | Buy |
| TCI Chemical | K0020 | 3-Methyl-2-oxovaleric Acid >95.0%(GC)(T) | 1460-34-0 | 5g | $594 | 2026-04-30 | Buy |
| Biosynth | FM157432 | (±)-3-Methyl-2-oxovaleric acid | 1460-34-0 | 1g | $150 | 2026-06-04 | Buy |
| Biosynth | FM157432 | (±)-3-Methyl-2-oxovaleric acid | 1460-34-0 | 5g | $324.5 | 2026-06-04 | Buy |
3-Methyl-2-oxovaleric acid Chemical Properties, Uses, Production
Uses
3-Methyl-2-oxovaleric acid is a degradation product from Isoleucine. 3-Methyl-2-oxovaleric acid is a biomarker of mustard airway diseases (MADs) and uric acid stone[1][2].
Definition
ChEBI: A 2-oxo monocarboxylic acid that is valeric acid carrying oxo- and methyl substituents at C-2 and C-3, respectively. An alpha-keto acid analogue and metabolite of isoleucine in man, animals and bacteria. Used as a clinical marker for maple syrup urine disease (MSUD).
Synthesis Reference(s)
The Journal of Organic Chemistry, 39, p. 600, 1974 DOI: 10.1021/jo00919a004
in vivo
In uric acid stone urinary environment, the levels of 3-Methyl-2-oxovaleric acid is elevated [2].
IC 50
Human Endogenous Metabolite
References
[1] Ghoochani BFNM, et, al. Metabolomics diagnostic approach to mustard airway diseases: a preliminary study. Iran J Basic Med Sci. 2018 Jan;21(1):59-69. DOI:10.22038/IJBMS.2017.23792.5982
[2] Xu S, et al. Self-control study of multi-omics in identification of microenvironment characteristics in urine of uric acid stone. Sci Rep. 2024 Oct 24;14(1):25165. DOI:10.1038/s41598-024-76054-0
3-Methyl-2-oxovaleric acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Methyl-2-oxovaleric acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6743 | 52 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Latest Price from 3-Methyl-2-oxovaleric acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-17 | 3-Methyl-2-oxovaleric acid
1460-34-0
|
$30.00-40.00 | 96.25% | 10g | TargetMol Chemicals Inc. |
-
- 3-Methyl-2-oxovaleric acid
1460-34-0
- $30.00-40.00
- 96.25%
- TargetMol Chemicals Inc.
1460-34-0 (3-Methyl-2-oxovaleric acid) Related Search:
1of4
