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4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine structure

CAS No.: 23000-43-3

Chemical Name:: 4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

Synonyms: AKOS BBS-00002108;BUTTPARK 75\18-20;4-CHLORO-1-METHYLPYRAZOLO[3,4-D]PYRIMIDINE;4-Chloro-1-methyl-1H-pyrazol[3,4-d]pyrimidine;4-CHLORO-1-METHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE;1-Methyl-4-chloro-1H-pyrazolo[3,4-d]pyrimidine;1H-Pyrazolo[3,4-d]pyrimidine, 4-chloro-1-methyl-

CBNumber:: CB2226813

Molecular Formula:: C6H5ClN4

Molecular Weight:: 168.58

MDL Number:: MFCD00661967

MOL File:: 23000-43-3.mol

Last updated:2025-07-24 18:13:50

Product description	Number	Pack Size	Price
4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine	C368323	10mg	$45
4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine	C368323	50mg	$60
4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 95%	067568	1g	$60
4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 97.85%	CS-W018697	1g	$60
4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine	FC139482	500mg	$75
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4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine Properties

Melting point	102-104
Boiling point	294.6±20.0 °C(Predicted)
Density	1.59±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Store in freezer, under -20°C
pka	1.46±0.10(Predicted)
Appearance	White to yellow Solid
InChI	InChI=1S/C6H5ClN4/c1-11-6-4(2-10-11)5(7)8-3-9-6/h2-3H,1H3
InChIKey	AVFLNALVPBLGEV-UHFFFAOYSA-N
SMILES	C1=NC(Cl)=C2C=NN(C)C2=N1
CAS DataBase Reference	23000-43-3
FDA UNII	EAD5BMA4P6

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H332-H335

Precautionary statements

P261-P280-P305+P351+P338

Hazard Note

Harmful

HS Code

2933998090

NFPA 704

	1
2		0

4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C368323	4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine	23000-43-3	10mg	$45	2021-12-16	Buy
TRC	C368323	4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine	23000-43-3	50mg	$60	2021-12-16	Buy
Oakwood	067568	4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 95%	23000-43-3	1g	$60	2021-12-16	Buy
ChemScene	CS-W018697	4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 97.85%	23000-43-3	1g	$60	2021-12-16	Buy
Biosynth Carbosynth	FC139482	4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine	23000-43-3	500mg	$75	2021-12-16	Buy

Product number	Packaging	Price	Buy
C368323	10mg	$45	Buy
C368323	50mg	$60	Buy
067568	1g	$60	Buy
CS-W018697	1g	$60	Buy
FC139482	500mg	$75	Buy

4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine Chemical Properties,Uses,Production

Uses

4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine is a chlorine-substituted organic compound. It is a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.

Synthesis

5399-92-8

74-88-4

4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

23000-43-3

General procedure for the synthesis of 1-methyl-4-chloropyrazolo[3,4-d]pyrimidines from 4-chloro-1H-pyrazolo[3,4-d]pyrimidines (1.88 g, 0.012 mol) and iodomethane (2.56 g, 0.018 mol): 4-chloro-1H-pyrazolo[3,4-d]pyrimidines and NaH (0.864 g, 0.036 mol) suspension in anhydrous DMF (10 mL) was stirred for 30 min. Subsequently, iodomethane was added and the reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the reaction was quenched with 100 mL of water and extracted with EtOAc (60 mL x 3). The organic layers were combined and concentrated under reduced pressure to afford the target product 1-methyl-4-chloropyrazolo[3,4-d]pyrimidine. Yield: 70.8%; 1H-NMR (400 MHz, DMSO-d6) δ 8.85 (s, 1H), 8.44 (s, 1H), 4.08 (s, 3H).

References

[1] Comptes Rendus Chimie, 2017, vol. 20, # 9-10, p. 927 - 933
[2] Molecules, 2017, vol. 22, # 4,
[3] Patent: CN107383014, 2017, A. Location in patent: Paragraph 0079; 0080; 0081; 0082
[4] European Journal of Medicinal Chemistry, 2018, vol. 155, p. 210 - 228

4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine Preparation Products And Raw materials

Raw materials

1-METHYL-1,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE 4-Chloro-1H-pyrazolo[3,4-d]pyrimidine 4,6-Dichloro-5-pyrimidinecarbaldehyde Methylhydrazine Iodomethane

N,N-Dimethylformamide Sodium hydride

1of2

Preparation Products

1-Methyl-{N}-propyl-1{H}-pyrazolo[3,4-{d}]pyrimidin-4-amine (9-methyl-2,4,8,9-tetrazabicyclo[4.3.0]nona-1,3,5,7-tetraen-5-yl)hydrazine

4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine Suppliers

Global( 110)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49976	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	3999	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Accela ChemBio Inc.	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Fuxin Pharmaceutical	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Career Henan Chemica Co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from 4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-05-15	4-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine 23000-43-3	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd

4-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine
23000-43-3
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine Spectrum

4-CHLORO-1-METHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE(23000-43-3)¹HNMR

23000-43-3(4-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine)Related Search:

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AKOS BBS-00002141 IFLAB-BB F2129-0007 IFLAB-BB F2129-0006

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BUTTPARK 75\18-20 AKOS BBS-00002108 4-CHLORO-1-METHYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE 4-CHLORO-1-METHYLPYRAZOLO[3,4-D]PYRIMIDINE 4-Chloro-1-methyl-1H-pyrazol[3,4-d]pyrimidine 1-Methyl-4-chloro-1H-pyrazolo[3,4-d]pyrimidine 1H-Pyrazolo[3,4-d]pyrimidine, 4-chloro-1-methyl- 23000-43-3 Heterocycle-Pyrimidine series