Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine Structure
3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine structure
CAS No.
943026-40-2
Chemical Name:
3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine
Synonyms
3-chloro-6H,7H-[1,4]dioxino[2,3-c]pyridazine;3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine;[1,4]Dioxino[2,3-c]pyridazine, 3-chloro-6,7-dihydro-
CBNumber:
CB22452458
Molecular Formula:
C6H5ClN2O2
Molecular Weight:
172.57
MDL Number:
MFCD09907908
MOL File:
943026-40-2.mol
Last updated:2026-09-12 18:50:34
Request For Quotation

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine Properties

Boiling point 351.2±42.0 °C(Predicted)
Density 1.478±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 1.52±0.20(Predicted)
Appearance White to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H320-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix C61780 3-Chloro-6,7-dihydro-[1,4]dioxino[2,3-c]pyridazine >98% 943026-40-2 100mg $110 2026-05-06 Buy
Synthonix C61780 3-Chloro-6,7-dihydro-[1,4]dioxino[2,3-c]pyridazine >98% 943026-40-2 250mg $190 2026-05-06 Buy
Synthonix C61780 3-Chloro-6,7-dihydro-[1,4]dioxino[2,3-c]pyridazine >98% 943026-40-2 1g $730 2026-05-06 Buy
aablocks AA00IHYV 3-Chloro-6,7-Dihydro-[1,4]Dioxino[2,3-C]Pyridazine 97% 943026-40-2 100mg $77 2026-05-29 Buy
ACHEMBLOCK X196019 3-Chloro-6,7-dihydro-[1,4]dioxino[2,3-c]pyridazine 98.00% 943026-40-2 250MG $175 2026-05-27 Buy
Product number Packaging Price Buy
C61780 100mg $110 Buy
C61780 250mg $190 Buy
C61780 1g $730 Buy
AA00IHYV 100mg $77 Buy
X196019 250MG $175 Buy

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine Chemical Properties, Uses, Production

Synthesis

2-((3,6-dichloropyridazin-4-yl)oxy)ethan-1-ol

17284-80-9

3-CHLORO-6,7-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDAZINE

943026-40-2

General procedure for the synthesis of 3-chloro-6,7-dihydro[1,4]dioxohexa[2,3-c]pyridazine from the compound (CAS:17284-80-9): (c) 2-[(3,6-dichloro-4-pyridazinyl)oxy]ethanol (15.46 g; 0.0703 mol) containing the bromine derivative was dissolved in anhydrous dioxane (1.2 L). Lithium hydride (2.3 g; 0.28 mol) was added in batches and stirred under argon protection at room temperature for 1 h. The reaction was then heated to 110 °C overnight. Upon completion of the reaction, the reaction was quenched with wet dioxane and then quenched with ice water. The reaction solution was concentrated to half of the original volume, the pH was adjusted to 8 with 5 M hydrochloric acid and then evaporated to dryness. After addition of water, the residue was extracted with chloroform and the organic phase was dried over sodium sulfate and concentrated to give a white solid (12.4 g, ~77% yield, containing ~15% bromine derivative). Mass spectrometric analysis (positive ion electrospray) showed m/z 173/5 (Cl MH+) and 217/9 (Br MH+).

References

[1] Patent: US2008/221110, 2008, A1. Location in patent: Page/Page column 18
[2] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 10, p. 2464 - 2469
[3] Patent: WO2008/128953, 2008, A1. Location in patent: Page/Page column 32-33
[4] Patent: WO2008/128961, 2008, A1. Location in patent: Page/Page column 54-55
[5] Patent: WO2008/128942, 2008, A1. Location in patent: Page/Page column 124

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine synthesis

17284-80-9
943026-40-2
Synthesis of 3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine from 2-((3,6-dichloropyridazin-4-yl)oxy)ethan-1-ol

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine Preparation Products And Raw materials

Raw materials

2-((3,6-dichloropyridazin-4-yl)oxy)ethan-1-ol Lithium hydride 1,4-Dioxane

Preparation Products

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine Suppliers

Global Suppliers ( 19)
Supplier Tel Email Country ProdList Advantage
RuiErKang Pharmaceuticals, Inc. 2921645477 2921645477@qq.com China 132 58
BePharm Ltd 400-685-9117 market@bepharm.com China 15081 60
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 028-83379370 13880556291 tcy@tcypharm.com China 8696 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9957 58
Shanghai Latchem Co., Ltd. 021-61916491 15921747686 sales@latcheminc.com China 967 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9718 58
Shanghai zhigan biotechnology co., LTD zhiqianbio@126.com China 19765 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49299 58
Taizhou Nanfeng Pharmaceutical Research Institute nanfengpharma@126.co 18616377689 nanfengpharma@126.com China 20008 58
Supplier Advantage
RuiErKang Pharmaceuticals, Inc. 58
BePharm Ltd 60
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 58
Amadis Chemical Company Limited 58
Hangzhou Molcore Biopharmatech Co.,Ltd 58
Shanghai Latchem Co., Ltd. 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
Shanghai zhigan biotechnology co., LTD 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 58
Taizhou Nanfeng Pharmaceutical Research Institute 58

3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine Spectrum

3-CHLORO-6,7-DIHYDRO[1,4]DIOXINO[2,3-C]PYRIDAZINE(943026-40-2)1HNMR

943026-40-2 (3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine) Related Search:

Chlorine dioxide 4-Methoxypyridazine 3-Chloro-5-methoxypyridazine 3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine 6-Chloro-3,4-dimethoxypyridazine
[1,4]Dioxino[2,3-c]pyridazine, 3-bromo-6,7-dihydro-

1of2

[1,4]Dioxino[2,3-c]pyridazine, 3-chloro-6,7-dihydro- 3-chloro-6H,7H-[1,4]dioxino[2,3-c]pyridazine 3-Chloro-6,7-dihydro[1,4]dioxino[2,3-c]pyridazine 943026-40-2