2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
- CAS No.
- 5466-43-3
- Chemical Name:
- 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
- Synonyms
- EOS-60937;4-dichloro-6;7-dihydro-5H-cyclopenta[d]pyriMidine;2,4-Dichloro-5,6-trimethylenepyrimidine;2,4-Dichloro-5H,6H,7H-cyclopenta[d]pyrimidine;2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE;5H-Cyclopentapyrimidine, 2,4-dichloro-6,7-dihydro-;2,4-dichloro-6,7-dihydro-1H-cyclopenta[d]pyrimidine;2,4-dichloro-6,7-dihydro-5H-cyclopenta[d][1,3]chlorazine;2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
- CBNumber:
- CB22460947
- Molecular Formula:
- C7H6Cl2N2
- Molecular Weight:
- 189.04
- MDL Number:
- MFCD09750204
- MOL File:
- 5466-43-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine 95% | 762296 | 1g | $98.03 |
| 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine | D438133 | 10mg | $45 |
| 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine | FD32826 | 500mg | $100 |
| 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine 99.87% | CS-W008301 | 5g | $157 |
| 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine | FD32826 | 1g | $157.5 |
| More product size | |||
| Melting point | 70-72℃ |
|---|---|
| Boiling point | 307℃ |
| Density | 1.466 |
| Flash point | 168℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | -1.78±0.20(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChIKey | GDHHAOFBLGZCMI-UHFFFAOYSA-N |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 762296 | 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine 95% | 5466-43-3 | 1g | $98.03 | 2025-07-31 | Buy |
| TRC | D438133 | 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine | 5466-43-3 | 10mg | $45 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD32826 | 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine | 5466-43-3 | 500mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-W008301 | 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine 99.87% | 5466-43-3 | 5g | $157 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD32826 | 2,4-Dichloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine | 5466-43-3 | 1g | $157.5 | 2021-12-16 | Buy |
2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE Chemical Properties,Uses,Production
Synthesis
![6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diol](/CAS/GIF/5466-00-2.gif)
5466-00-2
5466-43-3
General procedure for the synthesis of 2,4-dichloro-5,6-trimethylpyrimidine from 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione: 6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione (0.3 g, 1.97 mmol) was suspended in phosphorochloridic acid (5 ml) and heated to reflux overnight. Upon completion of the reaction, the reaction mixture was cooled to room temperature followed by slow addition of water under ice bath conditions. The precipitated product was collected by filtration and dried to give 2,4-dichloro-5,6-trimethylpyrimidine as a yellow solid. Yield: 92%. 1H NMR (DMSO-d6, 300 MHz): δ 3.13 (t, 2H, cyclopentyl-CH2), 3.00 (t, 2H, cyclopentyl-CH2), 2.23 (m, 2H, cyclopentyl-CH2).
References
[1] European Journal of Medicinal Chemistry, 1980, vol. 15, # 4, p. 317 - 322
[2] European Journal of Medicinal Chemistry, 2015, vol. 92, p. 246 - 256
[3] Patent: US2010/144731, 2010, A1. Location in patent: Page/Page column 22
[4] Patent: US2007/281949, 2007, A1. Location in patent: Page/Page column 93-94
[5] Patent: US2014/179668, 2014, A1. Location in patent: Paragraph 0829
2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 20386 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
View Lastest Price from 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-12-08 | 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
5466-43-3
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-12-26 | 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
5466-43-3
|
US $1.00 / KG | 1KG | 99% | 1000KGS | Career Henan Chemical Co |
-
- 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
5466-43-3
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 2,4-DICHLORO-6,7-DIHYDRO-5H-CYCLOPENTAPYRIMIDINE
5466-43-3
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
