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Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol structure

CAS No.: 120924-80-3

Chemical Name:: Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol

Synonyms: Aids007341;Aids-007341;Rac-(2R*,3R*)-2-(2,4-difluorophenyl)-3-(methylsulfonyl)-1-(1,2,4-triazol-1-yl)-2-butanol;1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-[(1R)-1-(methylsulfonyl)ethyl]-, (αR)-rel-

CBNumber:: CB22493477

Molecular Formula:: C13H15F2N3O3S

Molecular Weight:: 331.34

MDL Number:

MOL File:: 120924-80-3.mol

MSDS File:: SDS

Last updated:2026-05-11 16:31:51

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Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Properties

Boiling point	594.3±60.0 °C(Predicted)
Density	1.42±0.1 g/cm3(Predicted)
pka	11.11±0.29(Predicted)
FDA UNII	1BFZ5CM687

Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Chemical Properties, Uses, Production

Uses

SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research[1].

References

[1] Tanio T, et al. In vivo efficacy of SM-8668 (Sch 39304), a new oral triazole antifungal agent. Antimicrob Agents Chemother. 1990 Jun;34(6):980-4. DOI:10.1128/AAC.34.6.980

Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Suppliers

Global Suppliers ( 4)

Supplier	Tel	Email	Country	ProdList	Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3493	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58

Supplier	Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Latest Price from Threo-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	Sch 39304 120924-80-3	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

Sch 39304
120924-80-3
$1520.00-2500.00
TargetMol Chemicals Inc.

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Aids007341 Aids-007341 Rac-(2R*,3R*)-2-(2,4-difluorophenyl)-3-(methylsulfonyl)-1-(1,2,4-triazol-1-yl)-2-butanol 1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-[(1R)-1-(methylsulfonyl)ethyl]-, (αR)-rel- 120924-80-3