2,5-Dibromophenylacetic acid
- CAS No.
- 203314-28-7
- Chemical Name:
- 2,5-Dibromophenylacetic acid
- Synonyms
- Dibromophenylacetic acid;5-Dibromophenylacetic acid;2,5-Dibromophenylacetic acid;2,5-Dibromobenzeneacetic acid;Benzeneacetic acid, 2,5-dibromo-;2-(2,5-DibroMophenyl)acetic acid
- CBNumber:
- CB22503585
- Molecular Formula:
- C8H6Br2O2
- Molecular Weight:
- 293.94
- MDL Number:
- MFCD02664691
- MOL File:
- 203314-28-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-(2,5-Dibromophenyl)acetic acid Asreported | 273203 | 500mg | $382 |
| 2-(2,5-Dibromophenyl)acetic acid Asreported | 273203 | 1g | $535 |
| 2-(2,5-Dibromophenyl)acetic acid Asreported | 273203 | 2g | $761 |
| 2-(2,5-Dibromophenyl)acetic acid Asreported | 273203 | 5g | $1055 |
| 2-(2,5-Dibromophenyl)acetic acid Asreported | 273203 | 10g | $1274 |
| More product size | |||
| Boiling point | 376.4±27.0 °C(Predicted) |
|---|---|
| Density | 1.969±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | claggy powder |
| pka | 3.87±0.10(Predicted) |
| color | Cream to faint tan |
| InChI | InChI=1S/C8H6Br2O2/c9-6-1-2-7(10)5(3-6)4-8(11)12/h1-3H,4H2,(H,11,12) |
| InChIKey | NKZKFWYEXDBOTP-UHFFFAOYSA-N |
| SMILES | C1(CC(O)=O)=CC(Br)=CC=C1Br |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H332-H315-H319-H335 |
| Precautionary statements | P260-P280-P312 |
| HS Code | 2916399090 |
| REACH Registrations | Inactive |
2,5-Dibromophenylacetic acid price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 273203 | 2-(2,5-Dibromophenyl)acetic acid Asreported | 203314-28-7 | 500mg | $382 | 2026-06-03 | Buy |
| Usbiological | 273203 | 2-(2,5-Dibromophenyl)acetic acid Asreported | 203314-28-7 | 1g | $535 | 2026-06-03 | Buy |
| Usbiological | 273203 | 2-(2,5-Dibromophenyl)acetic acid Asreported | 203314-28-7 | 2g | $761 | 2026-06-03 | Buy |
| Usbiological | 273203 | 2-(2,5-Dibromophenyl)acetic acid Asreported | 203314-28-7 | 5g | $1055 | 2026-06-03 | Buy |
| Usbiological | 273203 | 2-(2,5-Dibromophenyl)acetic acid Asreported | 203314-28-7 | 10g | $1274 | 2026-06-03 | Buy |
2,5-Dibromophenylacetic acid Chemical Properties,Uses,Production
Uses
2-(2,5-Dibromophenyl)acetic Acid is used as a reactant in the synthesis of MK-8742, a HCV NS5a inhibitor.
Synthesis
74533-21-4
203314-28-7
In a 500 mL four-necked reaction flask, 82 g of 2-(2,5-dibromophenyl)acetonitrile was added to 400 mL of aqueous 2 N sodium hydroxide, and the mixture was heated to 100 °C and refluxed. The reaction progress was monitored by TLC. After completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted with 36% hydrochloric acid by slow dropwise addition to 8. The aqueous layer was separated by extraction with ethyl acetate. Subsequently, the pH of the aqueous layer was adjusted to 1-2 with 36% hydrochloric acid, at which point a solid precipitated. The off-white solid 2-(2,5-dibromophenyl)acetic acid was collected by filtration and dried to give 73 g in 83% yield.
References
[1] Patent: CN107759459, 2018, A. Location in patent: Paragraph 0007; 0008; 0017; 0018
[2] Synlett, 2011, # 17, p. 2525 - 2528
[3] Journal of Medicinal Chemistry, 2006, vol. 49, # 12, p. 3563 - 3580
2,5-Dibromophenylacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +86-18530059196 | sale04@alfachem.cn | China | 9666 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
| ChemExpress | +86-021-58950125 | info@chemexpress.com | China | 790 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 | sales@anikare.com | China | 9993 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
View Lastest Price from 2,5-Dibromophenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 2,5-Dibromophenylacetic acid
203314-28-7
|
$7.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 2,5-Dibromophenylacetic acid
203314-28-7
- $7.00
- 99%
- Career Henan Chemical Co
