3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester
- CAS No.
- 79128-68-0
- Chemical Name:
- 3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester
- Synonyms
- methyl 3-[(trifluoroacetyl)amino]thiophene-2-carboxylate;Methyl 3-(2,2,2-trifluoroacetaMido)thiophene-2-carboxylate;3-(N-TrifluoroacetylaMino)thiophene-2-carboxylic acid Methyl ester;3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester;3-(N-Trifluoroacetylamino)thiophene-2-carboxylic acid methyl ester, 97.5%;2-Thiophenecarboxylic acid, 3-[(2,2,2-trifluoroacetyl)amino]-, methyl ester
- CBNumber:
- CB22550448
- Molecular Formula:
- C8H6F3NO3S
- Molecular Weight:
- 253.2
- MDL Number:
- MFCD00103374
- MOL File:
- 79128-68-0.mol
| Product description | Number | Pack Size | Price |
| Methyl3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate >97.0% | CS-0030396 | 1g | $24 |
| Methyl3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate >97.0% | CS-0030396 | 5g | $84 |
| Methyl3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate >97.0% | CS-0030396 | 10g | $141 |
| Methyl 3-(2,2,2-trifluoroacetamido)-thiophene-2-carboxylate 95+% | 090763 | 250mg | $364 |
| METHYL-3-(2,2,2-TRIFLUOROACETAMIDO)THIOPHENE-2-CARBOXYLATE 95.00% | HCH0369223 | 5MG | $502.19 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Safety Statements | 24/25 |
| HS Code | 29349990 |
3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0030396 | Methyl3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate >97.0% | 79128-68-0 | 1g | $24 | 2021-12-16 | Buy |
| ChemScene | CS-0030396 | Methyl3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate >97.0% | 79128-68-0 | 5g | $84 | 2021-12-16 | Buy |
| ChemScene | CS-0030396 | Methyl3-(2,2,2-trifluoroacetamido)thiophene-2-carboxylate >97.0% | 79128-68-0 | 10g | $141 | 2021-12-16 | Buy |
| Matrix Scientific | 090763 | Methyl 3-(2,2,2-trifluoroacetamido)-thiophene-2-carboxylate 95+% | 79128-68-0 | 250mg | $364 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0369223 | METHYL-3-(2,2,2-TRIFLUOROACETAMIDO)THIOPHENE-2-CARBOXYLATE 95.00% | 79128-68-0 | 5MG | $502.19 | 2021-12-16 | Buy |
3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester Chemical Properties,Uses,Production
Synthesis
22288-78-4
407-25-0
79128-68-0
To a stirred solution of methyl 3-amino-2-thiophenecarboxylate (25.0 g, 159 mmol) in acetonitrile (325 mL) was added sequentially pyridine (15.5 mL) and trifluoroacetic anhydride (29.3 mL) at 0 °C. After 5 minutes of reaction, the reaction mixture was slowly warmed to room temperature and stirring was continued for 20 minutes. Subsequently, the reaction mixture was slowly poured into ice water (3.0 L) and stirred for 15 minutes to quench the reaction. The resulting precipitate was collected by filtration, washed with cold water and dried under vacuum to afford methyl 3-(2,2,2-trifluoroacetamido)-2-thiophenecarboxylate (37.3 g, 93% yield) as a pink solid. Its 1H NMR (300 MHz, DMSO-d6) data were as follows: δ 3.86 (3H, s), 7.72 (1H, d, J = 5.4 Hz), 8.03 (1H, d, J = 5.4 Hz), 11.17 (1H, br s).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 9, p. 2535 - 2539
[2] Journal of Medicinal Chemistry, 2016, vol. 59, # 13, p. 6293 - 6302
[3] Patent: WO2010/101302, 2010, A1. Location in patent: Page/Page column 129-130
[4] Patent: WO2005/47293, 2005, A1. Location in patent: Page/Page column 28
[5] Patent: WO2007/71434, 2007, A1. Location in patent: Page/Page column 27
3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester Preparation Products And Raw materials
Raw materials
Preparation Products
3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9215 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20342 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Allfluoro pharmaceutical co. ltd. | +86-400-0216110 +86-15958047586 | sales@allfluoro.com | China | 11385 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16514 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4169 | 58 |
| Shanghai Witofly Chemical Co.,Ltd | sales@witofly.com | China | 2864 | 52 |
View Lastest Price from 3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2021-07-13 | 3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester
79128-68-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-10 | 3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester
79128-68-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2020-01-03 | 3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester
79128-68-0
|
US $1.00 / KG | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- 3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester
79128-68-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester
79128-68-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-(2,2,2-trifluoro-acetylaMino)-thiophene-2-carboxylicacidMethylester
79128-68-0
- US $1.00 / KG
- 95-99%
- Career Henan Chemical Co
