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INCB 3284 diMesylate

INCB 3284 diMesylate Structure
INCB 3284 diMesylate structure
CAS No.
887401-93-6
Chemical Name:
INCB 3284 diMesylate
Synonyms
Dimesylate;INCB3284;N-[2-({(3R)-1-[trans-4-Hydroxy-4-(6-Methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl}aMino)-2-oxoethyl]-3-(trifluoroMethyl)benzaMide Methanesulfonate (1:2);CS-352;INCB3284 mesylate;INCB 3284 biMesylate;INCB 3284 diMesylate;INCB 3284 dimesylate, >=98%;N-[2-[[(3R)-1-[4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide;N-[2-[[(3R)-1-[4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide,methanesulfonic acid
CBNumber:
CB22552604
Molecular Formula:
C26H31F3N4O4
Molecular Weight:
520.5439496
MDL Number:
MFCD20926352
MOL File:
887401-93-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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INCB 3284 diMesylate Properties

storage temp. Store at -20°C
solubility DMF:11.0(Max Conc. mg/mL);15.43(Max Conc. mM)
DMSO:57.19(Max Conc. mg/mL);80.24(Max Conc. mM)
PBS (pH 7.2):5.0(Max Conc. mg/mL);7.02(Max Conc. mM)
Water:71.28(Max Conc. mg/mL);100.0(Max Conc. mM)
form Powder
color Colorless to light yellow
InChIKey PNPNUHKICDECDH-SEBNIYPMSA-N
FDA UNII 5ET5U3KG6K
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

INCB 3284 diMesylate price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 11963 INCB 3284 (dimesylate) ≥95% 887401-93-6 1mg $40 2026-04-30 Buy
Cayman Chemical 11963 INCB 3284 (dimesylate) ≥95% 887401-93-6 5mg $104 2026-04-30 Buy
Cayman Chemical 11963 INCB 3284 (dimesylate) ≥95% 887401-93-6 10mg $128 2026-04-30 Buy
Cayman Chemical 11963 INCB 3284 (dimesylate) ≥95% 887401-93-6 50mg $589 2026-04-30 Buy
Usbiological 255506 INCB 3284 dimesylate Asreported 887401-93-6 10mg $516 2026-06-03 Buy
Product number Packaging Price Buy
11963 1mg $40 Buy
11963 5mg $104 Buy
11963 10mg $128 Buy
11963 50mg $589 Buy
255506 10mg $516 Buy

INCB 3284 diMesylate Chemical Properties, Uses, Production

Uses

Dimesylate is a potent, selective, and orally bioavailable hCCR2 antagonist.

Biological Activity

Primary Target
human CCR2 (hCCR2)', 'Target IC50: 3.7 nM, 4.7 nM, and 84 nM for different assays.

in vivo

INCB 3284 (1 mg/kg/day, ip) reduces liver damage, and decreases microglia activation in AOM-treated mice via inhibition on CCR2. INCB 3284 also significantly reduces the pERK1/2 to tERK1/2 ratio, as well as G-protein signaling pathway activity and proinflammatory cytokine production in cortex lysates from mice administed with azoxymethane[2].

IC 50

MCP-1-hCCR2: 3.7 nM (IC50)

storage

Store at -20°C

INCB 3284 diMesylate Preparation Products And Raw materials

Raw materials

Preparation Products

INCB 3284 diMesylate Suppliers

Global Suppliers ( 86)
Supplier Tel Email Country ProdList Advantage
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
China Langchem Inc. 0086-21-58956006 China 7798 57
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 China 1490 55
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
Shanghai HuanChuan Industry Co.,Ltd. 021-61478794 sales@hcshhai.com China 9781 50
AdooQ Bioscience CHINA 025-58849295 info@adooq.cn China 2981 60
SPIRO PHARMA eric_feng1954@126.com China 313 55
Supplier Advantage
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
China Langchem Inc. 57
BOC Sciences 65
NCE Biomedical Co.,Ltd. 55
MedChemexpress LLC 58
AdooQ BioScience, LLC 58
Shanghai HuanChuan Industry Co.,Ltd. 50
AdooQ Bioscience CHINA 60
SPIRO PHARMA 55

View Latest Price from INCB 3284 diMesylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
INCB 3284 dimesylate pictures 2026-07-27 INCB 3284 dimesylate
887401-93-6
 $185.00-2570.00 10g TargetMol Chemicals Inc.

887401-93-6 (INCB 3284 diMesylate) Related Search:

INCB 3284 diMesylate INCB 3284 incb057643 INCB3344 3-Pyrrolidinecarboxylic acid, 1-[[7-cyano-2-[3'-[[3-[[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]-1,7-naphthyridin-8-yl]amino]-2,2'-dimethyl[1,1'-biphenyl]-3-yl]-5-benzoxazolyl]methyl]-, (3R)-
Cyclobutanecarboxylic acid, 1-[[4-(methoxymethyl)-4-[[[(1R,2S)-2-phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]-, hydrochloride (1:2)

1of2

INCB 3284 diMesylate INCB 3284 biMesylate N-[2-({(3R)-1-[trans-4-Hydroxy-4-(6-Methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl}aMino)-2-oxoethyl]-3-(trifluoroMethyl)benzaMide Methanesulfonate (1:2) INCB 3284 dimesylate, >=98% N-[2-[[(3R)-1-[4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide,methanesulfonic acid N-[2-[[(3R)-1-[4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide CS-352 N-[2-[[(3R)-1-[trans-4-Hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-benzamide dimethanesulfonate INCB3284 mesylate Dimesylate INCB3284 887401-93-6 C26H31F3N4O42CH4O3S C28H39F3N4O10S2