1-(ethoxycarbonyl)cyclopropanecarboxylic acid
- CAS No.
- 3697-66-3
- Chemical Name:
- 1-(ethoxycarbonyl)cyclopropanecarboxylic acid
- Synonyms
- Ethyl cyclopropane-1,1-dicarboxylate;Monoethyl 1,1-cyclopropanedicarboxylate;hoxycarbonyl)cyclopropanecarboxylic acid;1-(ethoxycarbonyl)cyclopropanecarboxylic acid;Cyclopropane-1,1-dicarboxylic acid ethyl ester;1,1-Cyclopropanedicarboxylic acid, 1-ethyl ester;2-METHYL-2-PROPANYL [(3R)-3-MORPHOLINYLMETHYL]CARBAMATE;1-(Ethoxycarbonyl)Cyclopropanecarboxylic Acid(WXC03382)
- CBNumber:
- CB22565941
- Molecular Formula:
- C7H10O4
- Molecular Weight:
- 158.15
- MDL Number:
- MFCD08690114
- MOL File:
- 3697-66-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | OR480622 | 1g | $21 |
| 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | OR480622 | 5g | $26 |
| 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | OR480622 | 25g | $89 |
| 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | OR480622 | 100g | $353 |
| 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | OR480622 | 500g | $1550 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2917200090 |
1-(ethoxycarbonyl)cyclopropanecarboxylic acid price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR480622 | 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | 3697-66-3 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR480622 | 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | 3697-66-3 | 5g | $26 | 2026-06-04 | Buy |
| Apolloscientific | OR480622 | 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | 3697-66-3 | 25g | $89 | 2026-06-04 | Buy |
| Apolloscientific | OR480622 | 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | 3697-66-3 | 100g | $353 | 2026-06-04 | Buy |
| Apolloscientific | OR480622 | 1-Ethoxycarbonylcyclopropanecarboxylic acid 95% | 3697-66-3 | 500g | $1550 | 2026-06-04 | Buy |
1-(ethoxycarbonyl)cyclopropanecarboxylic acid Chemical Properties,Uses,Production
Uses
1-(Ethoxycarbonyl)cyclopropanecarboxylic Acid is used in preparation of broad-spectrum anticancer medicine cabozantinib.
Synthesis
1559-02-0
3697-66-3
1-(Ethoxycarbonyl)cyclopropanecarboxylic acid was synthesized as follows: A solution of diethyl 1,1-cyclopropanedicarboxylate (20 g) in 1N NaOH (107 mL) and ethanol (220 mL) was hydrolyzed for 16 hours. Ethanol was removed by decompression distillation. The remaining starting material was extracted with ethyl acetate. The aqueous layer was acidified with 1N HCl. The reaction mixture was then extracted with ethyl acetate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to afford 1-(ethoxycarbonyl)cyclopropanecarboxylic acid in 94% yield. 1H NMR (CDCl3) δ 1.06 (t, 3H), 1.53 (m, 2H), 1.62 (m, 2H), 4.21 (q, 2H). ESI-MS: m/z 159 [M+H]+ for C7H10O4.
References
[1] Patent: WO2005/79812, 2005, A1. Location in patent: Page/Page column 45-46
[2] Patent: CN105111155, 2018, B. Location in patent: Paragraph 0038; 0051; 0055; 0056
[3] Patent: US2008/45556, 2008, A1. Location in patent: Page/Page column 21
[4] Patent: US2010/239576, 2010, A1
1-(ethoxycarbonyl)cyclopropanecarboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3998 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Lianyungang happen teng technology co., LTD | 15950718863 | wang666xt@163.com | CHINA | 295 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 | sales@tianpharm.com | CHINA | 304 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 17259 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
View Lastest Price from 1-(ethoxycarbonyl)cyclopropanecarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 1-(ethoxycarbonyl)cyclopropanecarboxylic acid
3697-66-3
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
||
 |
2024-07-20 | 1-(ethoxycarbonyl)cyclopropanecarboxylic acid
3697-66-3
|
$1.00 | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2022-09-27 | 1-(ethoxycarbonyl)cyclopropanecarboxylic acid
3697-66-3
|
1kg | 99% | 1000kg | henan kanbei chemical co.,ltd |
-
- 1-(ethoxycarbonyl)cyclopropanecarboxylic acid
3697-66-3
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 1-(ethoxycarbonyl)cyclopropanecarboxylic acid
3697-66-3
- $1.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-(ethoxycarbonyl)cyclopropanecarboxylic acid
3697-66-3
- $0.00
- 99%
- henan kanbei chemical co.,ltd
