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2-ethynylpyrazine

2-ethynylpyrazine Structure
2-ethynylpyrazine structure
CAS No.
153800-11-4
Chemical Name:
2-ethynylpyrazine
Synonyms
2-ethynylpyrazine;Pyrazine, 2-ethynyl-;2-Ethynylpyrazine 98%;2-Ethynylpyrazine - [E14588];2-Ethynyl-1,4-diazine, (Pyrazin-2-yl)acetylene
CBNumber:
CB22616270
Molecular Formula:
C6H4N2
Molecular Weight:
104.11
MDL Number:
MFCD13189804
MOL File:
153800-11-4.mol
MSDS File:
SDS
Last updated:2025-08-08 17:45:00
Product description Number Pack Size Price
2-Ethynylpyrazine E939208 10mg $45
2-Ethynylpyrazine 95+% E14588 100mg $80
2-Ethynylpyrazine 98% OR53022 250mg $102
2-Ethynylpyrazine 3H32-1-Y3 250mg $112
2-Ethynylpyrazine 97% AS110899 100mg $119
Request For Quotation

2-ethynylpyrazine Properties

Boiling point 180.3±20.0 °C(Predicted)
Density 1.11±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka -0.40±0.10(Predicted)
form crystalline solid
color Light gold to faint brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335-H302+H312+H332-H315
Precautionary statements  P261-P271-P280
HS Code  2933399990

2-ethynylpyrazine price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E939208 2-Ethynylpyrazine 153800-11-4 10mg $45 2021-12-16 Buy
Synthonix E14588 2-Ethynylpyrazine 95+% 153800-11-4 100mg $80 2021-12-16 Buy
Apolloscientific OR53022 2-Ethynylpyrazine 98% 153800-11-4 250mg $102 2021-12-16 Buy
SynQuest Laboratories 3H32-1-Y3 2-Ethynylpyrazine 153800-11-4 250mg $112 2021-12-16 Buy
Activate Scientific AS110899 2-Ethynylpyrazine 97% 153800-11-4 100mg $119 2021-12-16 Buy
Product number Packaging Price Buy
E939208 10mg $45 Buy
E14588 100mg $80 Buy
OR53022 250mg $102 Buy
3H32-1-Y3 250mg $112 Buy
AS110899 100mg $119 Buy

2-ethynylpyrazine Chemical Properties,Uses,Production

Synthesis

2-[2-(trimethylsilyl)ethynyl]pyrazine

291763-66-1

2-ethynylpyrazine

153800-11-4

To a solution of compound (CAS:291763-66-1) (3.0 g, 17.02 mmol) in THF (10 mL) was slowly added 1 M TBAF (tetrabutylammonium fluoride) solution over 9 min. The progress of the reaction was monitored by TLC (Thin Layer Chromatography) to confirm the complete conversion of the feedstock to the target product 2-alkynylpyrazines. After completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography to give 2-alkynylpyrazines (1.0 g, yield: 56.5%). LC-MS (Liquid Chromatography-Mass Spectrometry) analysis showed: m/z 105 ([M+H]+).

References

[1] Patent: WO2017/117708, 2017, A1. Location in patent: Page/Page column 18; 19
[2] Patent: WO2017/93544, 2017, A1. Location in patent: Page/Page column 97; 98
[3] Carbohydrate Research, 2011, vol. 346, # 9, p. 1083 - 1092
[4] Journal of Medicinal Chemistry, 2013, vol. 56, # 7, p. 3033 - 3047
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 7, p. 3532 - 3548

2-ethynylpyrazine synthesis

291763-66-1
153800-11-4
Synthesis of 2-ethynylpyrazine from 2-[2-(trimethylsilyl)ethynyl]pyrazine

2-ethynylpyrazine Preparation Products And Raw materials

Raw materials

3-Butyn-2-ol, 2-methyl-4-pyrazinyl- (9CI) 2-[2-(trimethylsilyl)ethynyl]pyrazine Tetrahydrofuran Tetrabutylammonium fluoride

Preparation Products

2-ethynylpyrazine Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29799 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-0519-85551759 +8613506123987 marketing1@neostarunited.com China 8826 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Changzhou AniKare Pharmatech Co., Ltd. 		+86-0519-8359-8696 +8618018249389 sales@anikare.com China 9942 58
Sichuan Biosynce Pharmatech Co., Ltd. 		+8619950309693 diane@biosynce.com China 4871 58
Suzhou ARTK Medchem Co., Ltd. 		+86-512-68323658 +86-18168183658 sales1@artkmedchem.com China 39002 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16516 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
Adamas Reagent, Ltd. 400-6009262 16621234537 chenyj@titansci.com China 14101 59
Wuhan ariel chemical Co., LTD. 18986259541 sales@3stc.com China 3842 58
Supplier Advantage
career henan chemical co 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Changzhou AniKare Pharmatech Co., Ltd. 		58
Sichuan Biosynce Pharmatech Co., Ltd. 		58
Suzhou ARTK Medchem Co., Ltd. 		58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
J & K SCIENTIFIC LTD. 76
Adamas Reagent, Ltd. 59
Wuhan ariel chemical Co., LTD. 58

View Lastest Price from 2-ethynylpyrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-ethynylpyrazine pictures 2020-01-13 2-ethynylpyrazine
153800-11-4
 US $5.00 / KG 1KG 98% 100KG Career Henan Chemical Co

2-ethynylpyrazine Spectrum

2-ethynylpyrazine(153800-11-4)1HNMR2-ethynylpyrazine(153800-11-4)FT-IR
2-ethynylpyrazine 2-Ethynyl-1,4-diazine, (Pyrazin-2-yl)acetylene 2-Ethynylpyrazine 98% Pyrazine, 2-ethynyl- 2-Ethynylpyrazine - [E14588] 153800-11-4