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3-Methoxyphenol

CAS No.
150-19-6
Chemical Name:
3-Methoxyphenol
Synonyms
m-Guaiacol;M-METHOXYPHENOL;Phenol, 3-methoxy-;RESORCINOL MONOMETHYL ETHER;NSC 21735;m-Methoxyphel;meta-guaiacol;3-Methxoyphenol;M-Hydroxyanisol;m-methoxy-pheno
CBNumber:
CB6202761
Molecular Formula:
C7H8O2
Molecular Weight:
124.14
MDL Number:
MFCD00002267
MOL File:
150-19-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:45:00
Product description Number Pack Size Price
3-Methoxyphenol 96% 328456 25g $63.9
3-Methoxyphenol 96% 328456 100g $121
3-Methoxyphenol >98.0%(GC) M0122 25mL $39
3-Methoxyphenol >98.0%(GC) M0122 100mL $96
3-Methoxyphenol ≥97% (GC) ≥97%(GC) 232019 25ml $184
More product size

3-Methoxyphenol Properties

Melting point -17 °C
Boiling point 113-115 °C/5 mmHg (lit.)
Density 1.131 g/mL at 25 °C (lit.)
refractive index n20/D 1.552(lit.)
FLAVIS Number 04.076 | 3-Methoxyphenol
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Liquid
pka 9.65(at 25℃)
color Clear pink-reddish to brown
Odor at 1.00%indipropylene glycol. phenolic
Water Solubility slightly soluble
BRN 1209898
Henry's Law Constant 1.7×102 mol/(m3Pa) at 25℃, Abraham et al. (1994)
Cosmetics Ingredients Functions SKIN CONDITIONING
InChI 1S/C7H8O2/c1-9-7-4-2-3-6(8)5-7/h2-5,8H,1H3
InChIKey ASHGTJPOSUFTGB-UHFFFAOYSA-N
SMILES COc1cccc(O)c1
LogP 1.340
CAS DataBase Reference 150-19-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII HXB7441U87
NIST Chemistry Reference 3-Methoxyphenol(150-19-6)
EPA Substance Registry System Phenol, 3-methoxy- (150-19-6)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
Signal word  Danger
Hazard statements  H302+H332-H311-H315-H318
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22-36/38-41-36/37/38-43-36-22
Safety Statements  26-36/37/39-46-37/39-24/25
RIDADR  UN 2810 6.1/PG 3
WGK Germany  3
RTECS  SL7524000
TSCA  TSCA listed
HazardClass  6.1
PackingGroup  III
HS Code  29095090
Storage Class 6.1C - Combustible, acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
Toxicity human,TCLo,inhalation,230ug/m3/22W (0.23mg/m3),BEHAVIORAL: IRRITABILITYBEHAVIORAL: MUSCLE WEAKNESSBEHAVIORAL: HEADACHE,Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 37(3), Pg. 108, 1972.
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
3 0

3-Methoxyphenol price More Price(83)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 328456 3-Methoxyphenol 96% 150-19-6 25g $63.9 2026-04-30 Buy
Sigma-Aldrich 328456 3-Methoxyphenol 96% 150-19-6 100g $121 2026-04-30 Buy
TCI Chemical M0122 3-Methoxyphenol >98.0%(GC) 150-19-6 25mL $39 2026-04-30 Buy
TCI Chemical M0122 3-Methoxyphenol >98.0%(GC) 150-19-6 100mL $96 2026-04-30 Buy
Usbiological 232019 3-Methoxyphenol ≥97% (GC) ≥97%(GC) 150-19-6 25ml $184 2026-06-03 Buy
Product number Packaging Price Buy
328456 25g $63.9 Buy
328456 100g $121 Buy
M0122 25mL $39 Buy
M0122 100mL $96 Buy
232019 25ml $184 Buy

3-Methoxyphenol Chemical Properties,Uses,Production

Chemical Properties

Clear pink red liquid

Uses

A phenol derivative, 3-Methoxyphenol can be used as catalysts and as building blocks in synthesis of organic compounds such as antioxidants.

Uses

3-Methoxyphenol may be used as an analytical standard for the determination of the analyte in wine, coffee beans, wood samples, and mainstream smoke by gas chromatography (GC) based techniques.

Preparation

synthesis of 3-methoxyphenol: The 1 mole of resorcinol is treated rapidly with stirring, in a three-necked flask provided with a reflux condenser, stirrer, internal thermometer, and dropping funnel, with 1.25 mole of 10% sodium hydroxide. With vigorous stirring, 1 mole of dimethyl sulfate is added in such a way that the temperature remains below 40° C (water cooling). To complete the reaction and to destroy unchanged dimethyl sulfate, the mixture is then heated for 30 min on a boiling water bath. After cooling, the organic layer is separated off and the aqueous solution is extracted several times with ether. The combined organic phases are washed with dilute sodium carbonate and then with water, dried with calcium chloride, and fractionated. Unchanged resorcinol can be recovered by acidifying the aqueous reaction solution and the wash water and extracting them with ether. The yield of 3-methoxyphenol is 50%, b.p. 113-115 °C/5 mm; b.p. 144°C/25mm; n20/D 1.552; d=1.131 g/mL at 25 °C.
Organicum. Practical Handbook of Organic Chemistry, by Heinz Becker, Werner Berger and Günter Domschke, Addison-Wesley Pub. Co, 206-207, (1973)

Definition

ChEBI: 3-methoxyphenol is a member of the class of phenols that is phenol having a methoxy-substituent at the 3-position. It is a member of phenols and a monomethoxybenzene. It derives from a resorcinol.

General Description

3-Methoxyphenol is a phenolic aroma compound typically present in food and beverage products.

Safety Profile

Poison by ingestion and intraperitoneal routes. Moderately toxic by skin contact. Human systemic effects by inhalation: muscle weakness, headache, and irritabdtty. Human female reproductive effects by inhalation: menstrual cycle changes and dsorders. A severe eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes. See also ETHERS.

10365-98-7
150-19-6
Synthesis of 3-Methoxyphenol from 3-Methoxyphenylboronic acid
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View Lastest Price from 3-Methoxyphenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Methoxyphenol pictures 2025-12-24 3-Methoxyphenol
150-19-6
1KG 99.0% 1000KG Shaanxi Dideu Medichem Co. Ltd
3-methoxyphenol pictures 2024-12-24 3-methoxyphenol
150-19-6
1Kg 99.9% 200tons airuikechemical co., ltd.
3-Methoxyphenol pictures 2023-05-27 3-Methoxyphenol
150-19-6
$100.00 25kg 99% 500t/month Henan Bao Enluo International TradeCo.,LTD
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  • 3-Methoxyphenol
    150-19-6
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RESORCINOL MONOMETHYL ETHER 3-Hydroxy phenyl methyl ether 3-Methoxyphenol,3-Hydroxyanisol RESORCINOLMETA-MONOMETHYLETHER META-METHOXYPHENOL m-Methoxyphel 3-Methoxyphenol ,98% 3-Hydroxyanisol, Resorcinol monomethyl ether 3-Methxoyphenol 3-Methoxyphenol,97% 3-Methoxyphenol, 97% 100ML M-Hydroxyanisol NSC 21735 3-Hydroxyanisole Resorcinol Monomethyl Ether Between Methoxy phenol 3-Methoxyphenol≥ 97% (GC) 3-Methoxy Phenol-Pure / 3-Hydroxyanisole 3-methyl-1,3-benzothiazol-2-imine M**3-METHOXYPHENOL m-Guaiacol m-methoxy-pheno Phenol, 3-methoxy- Phenol, m-methoxy- Resorcinol methyl ether resorcinolmethylether 3-methoxy-pheno 1-HYDROXY-3-METHOXYBENZENE 3-HYDROXYANISOL 3-HYDROXYANISOLE 3-METHOXYPHENOL M-HYDROXYANISOLE 3-Methoxyphenol> 3-metoksyfenol/3-Methoxyphenol meta-guaiacol Guaifenesin Impurity(3-methoxyphenol) Guaiacol EP Impurity H Guaiacol Impurity H 3 METHOXY PHENOLE 3-Hydroxyanisole in Methanol 3-Methoxyphenol, 96% M-METHOXYPHENOL 3-Methoxyphenol (ACI) 150-19-6 Oxygen Compounds Phenols Organic Building Blocks Building Blocks Building Blocks C6 to C8 Chemical Synthesis Organic Building Blocks Oxygen Compounds Phenols Aromatic Ethers Aromatics Intermediates & Fine Chemicals Pharmaceuticals bc0001