trans-caffeic acid
- CAS No.
- 501-16-6
- Chemical Name:
- trans-caffeic acid
- Synonyms
- trans-Caffeic acid;(E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid;C01197;AKOS B004050;trans-Caffeate;rans-Caffeicaci;（E)-CAFFEIC ACID;RARECHEM BK HC T335;TIMTEC-BB SBB006475;LABOTEST-BB LT00233168
- CBNumber:
- CB2281063
- Molecular Formula:
- C9H8O4
- Molecular Weight:
- 180.16
- MDL Number:
- MFCD00004392
- MOL File:
- 501-16-6.mol
- MSDS File:
- SDS
| Melting point | 211-213 °C (dec.)(lit.) |
|---|---|
| Boiling point | 416.8±35.0 °C(Predicted) |
| Density | 1.478±0.06 g/cm3(Predicted) |
| storage temp. | Storage temp. 2-8°C |
| solubility | ethanol: 50 mg/mL |
| form | powder |
| pka | 4.58±0.10(Predicted) |
| color | yellow to tan |
| BRN | 1954563 |
| Major Application | food and beverages |
| InChI | 1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2+ |
| InChIKey | QAIPRVGONGVQAS-DUXPYHPUSA-N |
| SMILES | OC(=O)\C=C\c1ccc(O)c(O)c1 |
| LogP | 1.420 (est) |
| CAS DataBase Reference | 501-16-6(CAS DataBase Reference) |
| FDA UNII | U2S3A33KVM |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H351 |
| Precautionary statements | P201-P308+P313 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-40-63-68-36 |
| Safety Statements | 26-36/37/39-36/37 |
| WGK Germany | 3 |
| RTECS | GD8950000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Carc. 2 |
trans-caffeic acid price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89547 | trans-Caffeic acid phyproof® Reference Substance | 501-16-6 | 100 mg | $521 | 2026-04-30 | Buy |
| Sigma-Aldrich | 51868 | trans-Caffeic acid certified reference material, TraceCERT | 501-16-6 | 50mg | $140 | 2026-04-30 | Buy |
| Biosynth | AAA50116 | trans-Caffeic acid | 501-16-6 | 500mg | $1050 | 2026-06-04 | Buy |
| Biosynth | AAA50116 | trans-Caffeic acid | 501-16-6 | 1000mg | $1470 | 2026-06-04 | Buy |
| ChemScene | CS-0081280 | trans-Caffeic acid ≥98% | 501-16-6 | 100mg | $74 | 2026-06-04 | Buy |
trans-caffeic acid Chemical Properties, Uses, Production
Uses
trans-Caffeic Acid is a useful synthetic intermediate. It was used as a reactant to synthesize N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. It is also used to prepare caffeic acid phenethyl ester analogs with antitumor structures.
Chemical Properties
Pale yellow crystalline powder
Uses
trans-Caffeic Acid is a useful synthetic intermediate. It was used as a reactant to synthesize N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. It is also used to prepare caffeic acid phenethyl ester analogs with antitumor structures.
Definition
ChEBI: Caffeic acid is a hydroxycinnamic acid that is cinnamic acid in which the phenyl ring is substituted by hydroxy groups at positions 3 and 4. It exists in cis and trans forms; the latter is the more common. It has a role as a plant metabolite, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, an EC 2.5.1.18 (glutathione transferase) inhibitor, an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor, an antioxidant and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a hydroxycinnamic acid and a member of catechols.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
IC 50
Microbial Metabolite
trans-caffeic acid Preparation Products And Raw materials
Raw materials
Preparation Products
trans-caffeic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Xiamen Dano Pharmaceutical Co., LTD(China) | 0592-6266840 15750707980; | chemdano@126.com | China | 411 | 57 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| Credit Asia Chemical Co., Ltd. | +86 (21) 61124340 | China | 9739 | 58 | |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Quzhou Rundong Chemical (Technology) Co. | 0570-8789886 18892685668 | info@rundongchemical.com | China | 4045 | 60 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 6904 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
View Latest Price from trans-caffeic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-03-05 | CAFFEIC ACID
501-16-6
|
$1.00 | 1KG | 98% HPLC | 10 tons | Career Henan Chemical Co |
-
- CAFFEIC ACID
501-16-6
- $1.00
- 98% HPLC
- Career Henan Chemical Co
