Dodecylphosphorylcholine-d38
- CAS No.
- 130890-78-7
- Chemical Name:
- Dodecylphosphorylcholine-d38
- Synonyms
- 12:0 D38 CP;MAPCHO-12-D38;MAPCHO(R)-12-d38;DODECYLPHOSPHOCHOLINE-D38;MAPCHO?-12-d38;D38-Dodecylphosphocholine;n-Dodecylphosphocholine-d38;Dodecylphosphorylcholine-d??;Dodecylphosphorylcholine-d38;Dodecylphosphocholine (D??, 98%)
- CBNumber:
- CB2284842
- Molecular Formula:
- C17D38NO4P
- Molecular Weight:
- 389.7
- MDL Number:
- MFCD01321393
- MOL File:
- 130890-78-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 247-249 °C(lit.) |
|---|---|
| storage temp. | -20°C |
| solubility | DMF: 16 mg/ml; DMSO: 16 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 25 mg/ml |
| form | A crystalline solid |
| pka | 1.276±0.50(predicted) |
| color | White to off-white |
| InChIKey | QBHFVMDLPTZDOI-DHIOKLJKSA-N |
| UNSPSC Code | 12352211 |
| NACRES | NA.25 |
| CAS Number Unlabeled | 29557-51-5 |
Dodecylphosphorylcholine-d38 price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 485616 | Dodecylphosphorylcholine-d38 98 atom % D | 130890-78-7 | 500mg | $1330 | 2026-04-30 | Buy |
| Cayman Chemical | 25996 | Dodecylphosphocholine-d38 ≥99%deuteratedforms(d1-d38) | 130890-78-7 | 25mg | $99 | 2026-04-30 | Buy |
| Cayman Chemical | 25996 | Dodecylphosphocholine-d38 ≥99%deuteratedforms(d1-d38) | 130890-78-7 | 50mg | $190 | 2026-04-30 | Buy |
| Cayman Chemical | 25996 | Dodecylphosphocholine-d38 ≥99%deuteratedforms(d1-d38) | 130890-78-7 | 100mg | $337 | 2026-04-30 | Buy |
| Cayman Chemical | 25996 | Dodecylphosphocholine-d38 ≥99%deuteratedforms(d1-d38) | 130890-78-7 | 250mg | $544 | 2026-04-30 | Buy |
Dodecylphosphorylcholine-d38 Chemical Properties, Uses, Production
Description
Dodecylphosphocholine-d38 is intended for use as an internal standard for the quantification of dodecylphosphocholine by GC- or LC-MS. Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR. It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane. Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) β-strand (PrP (110-136)). Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.
Uses
MAPCHO-12-d38 has been used in the preparation of drug complexes used as a sample during nuclear magnetic resonance (NMR) spectroscopy.
References
[1] VILIUS KURAUSKAS. How Detergent Impacts Membrane Proteins: Atomic-Level Views of Mitochondrial Carriers in Dodecylphosphocholine.[J]. The Journal of Physical Chemistry Letters, 2018, 9 5: 933-938. DOI: 10.1021/acs.jpclett.8b00269
[2] SARAH D. CADY. Specific Binding of Adamantane Drugs and Direction of Their Polar Amines in the Pore of the Influenza M2 Transmembrane Domain in Lipid Bilayers and Dodecylphosphocholine Micelles Determined by NMR Spectroscopy[J]. Journal of the American Chemical Society, 2011, 133 12: 4274-4284. DOI: 10.1021/ja102581n
[3] S. SAUVé Y A. Dodecylphosphocholine Micelles Induce Amyloid Formation of the PrP(110-136) Peptide via an α-Helical Metastable Conformation[J]. PLoS ONE, 2016, 11 1. DOI: 10.1371/journal.pone.0168021
Dodecylphosphorylcholine-d38 Preparation Products And Raw materials
Raw materials
Preparation Products
Dodecylphosphorylcholine-d38 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9656 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9383 | 58 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | kexin.zhou@haolvbiotech.com | China | 3009 | 58 |
| Qingdao Tenglong microwave technology co., LTD. | 0532-83818797 17669478191 | sc@tlwb.com.cn | China | 3933 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
