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Terazosin

Terazosin Structure
Terazosin structure
CAS No.
63590-64-7
Chemical Name:
Terazosin
Synonyms
TERAZOSIN HCL;terazosine;Urodie;HYTRIN;erazosin;arbonyl)-;Terazosin;CID 663211;Vasomet：Vicard;Hytrin：Hytrinex
CBNumber:
CB2285511
Molecular Formula:
C19H25N5O4
Molecular Weight:
387.43
MDL Number:
MFCD00072144
MOL File:
63590-64-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
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Terazosin Properties

Melting point 281-283°C
Boiling point 664.5±65.0 °C(Predicted)
Density 1.332±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility H2O: 25 mg/mL
form powder
pka pKa (0.1N NaOH): 7.1(at 25℃)
color white to off-white
Water Solubility 30.6mg/L(22.5 ºC)
BCS Class 1/3
InChIKey VCKUSRYTPJJLNI-UHFFFAOYSA-N
CAS DataBase Reference 63590-64-7(CAS DataBase Reference)
NCI Dictionary of Cancer Terms Hytrin
FDA UNII 8L5014XET7
ATC code G04CA03

Pharmacokinetic data

Protein binding 90-94%
Excreted unchanged in urine 10%
Volume of distribution 0.5-0.9(L/kg)
Biological half-life 9-12 / Unchanged

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P301+P312+P330
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  TK8044925
REACH Registrations Active

Terazosin price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-T105000-50MG Terazosin Hydrochloride 63590-64-7 50mg $75 2026-06-03 Buy
TRC TRC-T105000-250MG Terazosin Hydrochloride 63590-64-7 250mg $87 2026-06-03 Buy
TRC TRC-T105000-1G Terazosin Hydrochloride 63590-64-7 1g $141 2026-06-03 Buy
Biosynth FA28036 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonxyl]piperazine hydrochloride 63590-64-7 10g $6875 2026-06-04 Buy
Biosynth FA28036 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonxyl]piperazine hydrochloride 63590-64-7 25g $10312.5 2026-06-04 Buy
Product number Packaging Price Buy
TRC-T105000-50MG 50mg $75 Buy
TRC-T105000-250MG 250mg $87 Buy
TRC-T105000-1G 1g $141 Buy
FA28036 10g $6875 Buy
FA28036 25g $10312.5 Buy

Terazosin Chemical Properties, Uses, Production

Chemical Properties

White to Off-White Crystalline Powder

Uses

An α-1-adrenergicblocker related to prazosin.

Uses

Terazosin is used for the same indications as is prazosin; however, it has the advantage of being able to be used once a day.

Uses

An a-1-adrenergicblocker related to prazosin

Definition

ChEBI: Terazosin is a member of quinazolines, a member of piperazines, a member of furans and a primary amino compound. It has a role as an antineoplastic agent, an antihypertensive agent and an alpha-adrenergic antagonist.

Clinical Use

Alpha-adrenoceptor blocker:
Hypertension
Benign prostatic hyperplasia (BPH)

Synthesis

Terazosin, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)- piperazine (12.2.13), only differs from prazosin in that the furyl radical is replaced with a tetrahydrofuryl radical. It is synthesized in exactly the same manner except using 1-(2-tetrahydrofuroyl)piperazine instead of 1-(2-furoyl)piperazine [48–51].

Drug interactions

Potentially hazardous interactions with other drugs
Anaesthetics: enhanced hypotensive effect.
Antidepressants: enhanced hypotensive effect with MAOIs.
Avanafil, vardenafil, sildenafil and tadalafil: enhanced hypotensive effect - avoid concomitant use.
Beta-blockers: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
Calcium-channel blockers: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
Diuretics: enhanced hypotensive effect; increased risk of first dose hypotensive effect.
Moxisylyte: possibly severe postural hypotension when used in combination.

Metabolism

Terazosin is metabolised in the liver; one of the metabolites has antihypertensive activity.
Terazosin is excreted in faeces via the bile, and in the urine, as unchanged drug and metabolites.

Terazosin Preparation Products And Raw materials

Raw materials

2-Furoic acid Piperazine Quinazoline 2-Furoyl chloride Terazosin hydrochloride

Preparation Products

Terazosin Suppliers

Global Suppliers ( 169)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6741 52
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
GIHI CHEMICALS CO.,LTD 0086-571-86217390 Sales@gihichem.com China 858 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
LGM Pharma 70
Shanghai Longsheng chemical Co.,Ltd. 59
Chemsky（shanghai）International Co.,Ltd. 50
XiaoGan ShenYuan ChemPharm co,ltd 52
Beijing HuaMeiHuLiBiological Chemical 58
Shanghai T&W Pharmaceutical Co., Ltd. 58
MedChemexpress LLC 58
GIHI CHEMICALS CO.,LTD 58

View Latest Price from Terazosin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Terazosin pictures 2026-07-16 Terazosin
63590-64-7
 1kg 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
Terazosin pictures 2026-05-11 Terazosin
63590-64-7
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
Terazosin pictures 2022-02-25 Terazosin
63590-64-7
 $999.00 1KG 99% 1 ton Hong Kong Tiansheng New Material Trading Co., Ltd
  • Terazosin pictures
  • Terazosin
    63590-64-7
  • $0.00
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd
  • Terazosin pictures
  • Terazosin
    63590-64-7
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
  • Terazosin pictures
  • Terazosin
    63590-64-7
  • $999.00
  • 99%
  • Hong Kong Tiansheng New Material Trading Co., Ltd

Terazosin Spectrum

Terazosin(63590-64-7)MS

63590-64-7 (Terazosin) Related Search:

Piperacillin Dimethyldimethoxysilane N-Aminoethylpiperazine 6-Aminocaproic acid 1,1-Dimethoxyethane
Diphenyldimethoxysilane 3-Aminophenol Tris(hydroxymethyl)aminomethane Glycine Aminoethoxyvinyl glycine hydrochloride
Carbonyl sulfide Pyrazophos Terazosin hydrochloride dihydrate Terazosin hydrochloride TERAZOSIN RELATED COMPOUND B (50 MG) (1-(4-HYDROXY-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-[(TETRA-HYDRO-2-FURANYL)CARBONYL]PIPERAZINE)
TERAZOSIN RELATED COMPOUND C (25 MG) (1,4-BIS(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)PIPER-AZINE DIHYDROCHLORIDE) 2-chloro-4-amino-6,7-dimethoxyquinazoline (intermediate of terazosin) Quinazoline

1of4

1-(4-aMino-6,7-diMethoxy-quinazolin-2-yl)-4-(tetrahydrofuran-2-carbonyl)-piperazine TERAZOSIN(HYTRIN) Prazosin Tetrahydro IMpurity Hytrin：Hytrinex Urodie Vasomet：Vicard 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl) carbonxyl] piperazine hydrochloride 1-(4-Amino-6，7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbowl]piperazine Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-
 1-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-4-[(tetrahydrofuran-2-yl)carbonyl]piperazine [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-[(2S)-2-oxolanyl]methanone Methanone,[4-(4-aMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)- [4-(4-AMINO-6,7-DIMETHOXY-QUINAZOLIN-2-YL)PIPERAZIN-1-YL]-OXOLAN-2-YL-METHANONE 1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-[(TETRAHYDRO-2-FURANYL)CARBONXYL]PIPERAZINE, HYDROCHLORIDE HYTRIN TERAZOSIN MONOHYDROCHLORIDE 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)p arbonyl)- 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]- (9CI) 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-furanyl)carbonyl]piperazine 6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride Terazosin N-(2-tertrahydrofuroyl)-piperazine erazosin Terazosin USP/EP/BP 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-{(tetnaphydro-2-furanyl)carbonyl}piperazine CID 663211 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydrofuran-2-carbonyl)piperazine] TERAZOSIN HCL terazosine 63590-64-7 C19H29ClN5O6 C19H26ClN5O4 C19H28ClN5O6 C19H25N5O4 API's API Terazosin Intermediates & Fine Chemicals Pharmaceuticals