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Terazosin hydrochloride

Terazosin hydrochloride Structure
Terazosin hydrochloride structure
CAS No.
63074-08-8
Chemical Name:
Terazosin hydrochloride
Synonyms
Itrin;HYTRIN;Hitrin;Vicard;Blavin;Dysalfa;Flotrin;Heitrin;Hytrine;Olyster
CBNumber:
CB9285510
Molecular Formula:
C19H26ClN5O4
Molecular Weight:
423.9
MDL Number:
MFCD00467965
MOL File:
63074-08-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-20 23:19:27
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Terazosin hydrochloride Properties

Melting point 261-263°C
storage temp. Inert atmosphere,2-8°C
solubility H2O: 25 mg/mL
form powder
color white to off-white
Water Solubility Soluble in water at 20mg/ml. Also soluble in methanol or ethanol.
Stability Stable for 2 years as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
InChI InChI=1S/C19H25N5O4.ClH/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H
InChIKey IWSWDOUXSCRCKW-UHFFFAOYSA-N
SMILES NC1=NC(N2CCN(C(C3OCCC3)=O)CC2)=NC2=CC(OC)=C(OC)C=C12.Cl
CAS DataBase Reference 63074-08-8(CAS DataBase Reference)
NCI Dictionary of Cancer Terms terazosin hydrochloride
FDA UNII 8QOP8Z9955
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  TK8044925
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
NFPA 704
0
2 0

Terazosin hydrochloride price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T4680 Terazosin hydrochloride ≥98% (TLC), powder 63074-08-8 50mg $233 2026-04-30 Buy
Sigma-Aldrich T4680 Terazosin hydrochloride ≥98% (TLC), powder 63074-08-8 250mg $1010 2026-04-30 Buy
Cayman Chemical 20216 Terazosin (hydrochloride) ≥98% 63074-08-8 100mg $121 2026-04-30 Buy
Cayman Chemical 20216 Terazosin (hydrochloride) ≥98% 63074-08-8 250mg $240 2026-04-30 Buy
Cayman Chemical 20216 Terazosin (hydrochloride) ≥98% 63074-08-8 500mg $388 2026-04-30 Buy
Product number Packaging Price Buy
T4680 50mg $233 Buy
T4680 250mg $1010 Buy
20216 100mg $121 Buy
20216 250mg $240 Buy
20216 500mg $388 Buy

Terazosin hydrochloride Chemical Properties, Uses, Production

Description

Terazosin hydrochloride is a highly water-soluble antihypertensive agent with a structure and profile closely related to that of prazosin.

Originator

Abbott (USA)

Uses

An α-1-adrenergicblocker related to prazosin.

Uses

Terazosin hydrochloride has been used for orthogonality and similarity analysis using reversed-phase chromatographic studies5. Furthermore, terazosin has also been used for the evaluation of chemometric techniques to determine orthogonality and similarity in chromatographic methods6.

Uses

Hytrin (Abbott).

brand name

Terazosin is INN and BAN;HEITRIN.

General Description

Terazosin hydrochloride, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine monohydrochloride (Hytrin), is a structuralcongener of prazosin hydrochloride. It possessessimilar selective properties of specifically inhibiting 1-adrenergic receptors. The drug is slightly less potent thanprazosin hydrochloride. Terazosin hydrochloride has a halflifeof approximately 12 hours, which is much longer thanthat of prazosin. This lends itself to a once-daily dose tocontrol hypertension in many patients.

Biological Activity

α 1 - and α 2B -adrenoceptor antagonist (K i values are 3.3, 0.7, 1.1, 7.7, 1510 and 78.2 nM for α 1A , α 1B , α 1D , α 2B , α 2A and α 2C receptors respectively). Antihypertensive following oral or intravenous administration in vivo .

Biochem/physiol Actions

α1-adrenoceptor antagonist.

storage

Store at RT

References

[1] A A HANCOCK. Actions of terazosin and its enantiomers at subtypes of alpha 1- and alpha 2-adrenoceptors in vitro.[J]. Journal of Receptors and Signal Transduction, 1995, 15 7-8: 863-885. DOI:10.3109/10799899509049862
[2] PH.D. J J K. Pharmacology of terazosin[J]. American Journal of Medicine, 1986, 80 5: Pages 12-19. DOI:10.1016/0002-9343(86)90846-6
[3] H SHIONOIRI. Long-term therapy with terazosin may improve glucose and lipid metabolism in hypertensives: a multicenter prospective study.[J]. American Journal of the Medical Sciences, 1994, 307 Suppl 1: S91-5.
[4] SHIOW-LIN PAN. Identification of Apoptotic and Antiangiogenic Activities of Terazosin in Human Prostate Cancer and Endothelial Cells[J]. Journal of Urology, 2003, 169 2: Pages 724-729. DOI:10.1016/s0022-5347(05)64002-5
[5] XINPING CHEN. Terazosin activates Pgk1 and Hsp90 to promote stress resistance[J]. Nature chemical biology, 2014, 11 1: 19-25. DOI:10.1038/nchembio.1657

Terazosin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Terazosin

Terazosin hydrochloride Suppliers

Global Suppliers ( 284)
Supplier Tel Email Country ProdList Advantage
Hainan Ludao Pharmaceutical Co., Ltd. -- ld@hngip.com China 1 60
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Beijing HuaMeiHuLiBiological Chemical 010-56205725 waley188@sohu.com China 12323 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58
HBCChem, Inc. +1-510-219-6317 sales@hbcchem.com United States 10628 60
Supplier Advantage
Hainan Ludao Pharmaceutical Co., Ltd. 60
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Adamas Reagent, Ltd. 59
Syntechem Co.,Ltd 57
Beijing HuaMeiHuLiBiological Chemical 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Guangzhou Isun Pharmaceutical Co., Ltd 55
AdooQ BioScience, LLC 58
TargetMol Chemicals Inc. 58
HBCChem, Inc. 60

View Latest Price from Terazosin hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Terazosin hydrochloride pictures 2026-08-21 Terazosin hydrochloride
63074-08-8
 $37.00-137.00 99.91% 10g TargetMol Chemicals Inc.
Terazosin hydrochloride pictures 2026-08-21 Terazosin hydrochloride
63074-08-8
 $37.00-137.00 99.91% 10g TargetMol Chemicals Inc.
Terazosin hydrochloride pictures 2026-08-12 Terazosin hydrochloride
63074-08-8
 $121.00 1KG 99% 200T Baoji Guokang Healthchem Co., Ltd.

Terazosin hydrochloride Spectrum

Terazosin hydrochloride(63074-08-8)1HNMR

63074-08-8 (Terazosin hydrochloride) Related Search:

Cetirizine dihydrochloride Telmisartan TERAZOSIN HYDROCHLORIDE DIHYDRATE Terazosin hydrochloride 4-Amino-6,7-dimethoxyquinazoline
Terazosin Quinazoline Terazosin hydrochloride, anhydrous Terazosin hydrochloride dihydrateimp. L (EP): 1-(furan-2-ylcarbonyl)-piperazine Terazosin hydrochloride dihydrateimp. A (EP): 2-chloro-6,7-dimethoxyquinazolin-4-amine
Terazosin hydrochloride dihydrateimp. N (EP): 1-[[(2RS)-tetrahydrofuran-2-yl]carbonyl]piperazine Terazosin hydrochloride dihydrateimp. O (EP): 1,4-bis[(tetrahydrofuran-2-yl)carbonyl]piperazine Terazosin hydrochloride dihydrateimp. M (EP): 1,4-bis(furan-2-ylcarbonyl)piperazine (R)-(+)-Terazosin hydrochloride dihydrate Terazosin hydrochloride dihydrateimp. C (EP): 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine
Terazosin hydrochloride dihydrateimp. K (EP) as hydrochloride:prazosin hydrochloride Terazosin hydrochloride monohydrate

1of4

Tarazosin Hydrochloride [4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-tetrahydrofuran-2-yl-methanone hydrochloride Methanone,[4-(4-aMino-6,7-diMethoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-,hydrochloride (1:1) 6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride [4-(4-amino-6,7-dimethoxy-2-quinazolin-3-iumyl)-1-piperazinyl]-[(2R)-2-oxolanyl]methanone abbott-45975 piperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)c TERAZOSIN HCL TERAZOSIN HYDROCHLORIDE TERAZOSIN MONOHYDROCHLORIDE HYTRIN 1-(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-[(TETRAHYDRO-2-FURANYL)CARBONXYL]PIPERAZINE, HYDROCHLORIDE 1-[4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL]-4-([TETRAHYDRO-2-FURANYL]CARBONYL) PIPERAZINE HYDROCHLORIDE Tetrachlorphthalsureanhydrid s-(+-2-alaninol) Terazosin monohydrochloride anhydrous Terazosin hydrochloride anhydride [4-(4-AMINO-6,7-DIMETHOXY-QUINAZOLIN-2-YL)PIPERAZIN-1-YL]-OXOLAN-2-YL-METHANONE Tetrazosin hydrochloride 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine monohydrochloride 2-[4-(Tetrahydro-2-furoyl)-piperazine]-4-amino-6,7-dimethoxyquinazoline-hydrochloride Dysalfa Flotrin Heitrin Hitrin Hytracin Hytrine Itrin Olyster Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, monohydrochloride (9CI) Teralfa Tructum Vasocard Vasomet Vicard Zayasel Fosfomic Blavin Terazosin hydrochloride USP/EP/BP 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-fur... Terazosin hydrochlorideTerazosin hydrochloride Terazosin HydrochlorideQ: What is Terazosin Hydrochloride Q: What is the CAS Number of Terazosin Hydrochloride Q: What is the storage condition of Terazosin Hydrochloride Q: What are the applications of Terazosin Hydrochloride Terazocin HCl Terazosin hydrochloride salt 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](tetrahydrofuran-2-yl)methanone Terazosin hydrochloride, 10 mM in DMSO TERAZOSIN HYDROCHLORIDE USP (NON-STERILE DRUG SUBSTANCE) 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydrofuran-2-carbonyl)piperazine]hydrochloride 63074-08-8 63950-64-7 C19H25N5O4HCl C19H25N5O4ClH Terazosin (intermediate of levofloxacin) Adrenoceptor Pharmaceutical