GEODIN
- CAS No.
- 427-63-4
- Chemical Name:
- GEODIN
- Synonyms
- GEODIN;d-Geodin;(+)-ESTIN;(+)-Geodin;(+)-Form methyl ester;Geodin, PAI-1 (plasminogen activator inhibitor) inhibitor;methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxospiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate;methyl 5,7-dichloro-4-hydroxy-5'-methoxy-6-methyl-3,3'-dioxo-spiro[1-benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylate;5,7-dichloro-4-hydroxy-3,3'-diketo-5'-methoxy-6-methyl-spiro[benzofuran-2,6'-cyclohexa-1,4-diene]-1'-carboxylic acid methyl ester;SPIRO[BENZOFURAN-2(3H),1'-[2,5]CYCLOHEXADIENE]-2'-CARBOXYLIC ACID, 5,7-DICHLORO-4-HYDROXY-6'-METHOXY-6-METHYL-3,4'-DIOXO-, METHYL ESTER
- CBNumber:
- CB2287449
- Molecular Formula:
- C17H12Cl2O7
- Molecular Weight:
- 399.18
- MDL Number:
- MFCD00600308
- MOL File:
- 427-63-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 235℃ |
|---|---|
| alpha | D +140° (c = 0.8) |
| Boiling point | 652.1±55.0 °C(Predicted) |
| Density | 1.61±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Chloroform: soluble; DMSO: soluble; Ethyl Acetate: soluble; Methanol: soluble |
| form | A solid |
| pka | 5.17±0.60(Predicted) |
| color | Yellow |
| FDA UNII | 4293R7B06X |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P321-P330-P362+P364-P501 | |||||||||
| NFPA 704 |
|
GEODIN price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26421 | (+)-Geodin ≥95% | 427-63-4 | 1mg | $121 | 2026-04-30 | Buy |
| Cayman Chemical | 26421 | (+)-Geodin ≥95% | 427-63-4 | 5mg | $301 | 2026-04-30 | Buy |
| Usbiological | 592528 | Geodin | 427-63-4 | 1mg | $704 | 2026-06-03 | Buy |
| Usbiological | 592528 | Geodin | 427-63-4 | 5mg | $1381 | 2026-06-03 | Buy |
| Usbiological | 207211 | Geodin ≥95%(HPLC) | 427-63-4 | 1mg | $346 | 2026-06-03 | Buy |
GEODIN Chemical Properties,Uses,Production
Description
(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes.
Uses
Geodin is an inhibitor of plasminogen activator inhibitor (PAI-1).
storage
+4°C
References
[1] C SHINOHARA. Enhancement of fibrinolytic activity of vascular endothelial cells by chaetoglobosin A, crinipellin B, geodin and triticone B.[J]. Journal of Antibiotics, 2000, 53 3: 262-268. DOI: 10.7164/antibiotics.53.262
[2] SEIICHI SATO. Identification and Preliminary SAR Studies of (+)-Geodin as a Glucose Uptake Stimulator for Rat Adipocytes[J]. Journal of Antibiotics, 2005, 58 9: 583-589. DOI: 10.1038/ja.2005.79
GEODIN Preparation Products And Raw materials
Raw materials
Preparation Products
GEODIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903022 18679456698 | zilong@hizyme.com | China | 8001 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50089 | 58 |
View Lastest Price from GEODIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-07-27 | (+)-Geodin
427-63-4
|
$275.00-683.00 | 10g | TargetMol Chemicals Inc. |
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- (+)-Geodin
427-63-4
- $275.00-683.00
- TargetMol Chemicals Inc.
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