6-Methyl-2-pyridinecarboxaldehyde
- CAS No.
- 1122-72-1
- Chemical Name:
- 6-Methyl-2-pyridinecarboxaldehyde
- Synonyms
- 6-METHYLPICOLINALDEHYDE;6-METHYL-2-PYRIDINECARBALDEHYDE;6-METHYLPYRIDINE-2-CARBOXALDEHYDE;6-METHYLPYRIDINE-2-CARBOXYALDEHYDE;dehyde, 6-methyL;6-ForMyl-2-picoline;TIMTEC-BB SBB004287;2-FORMYL-6-PICOLINE;Chlorpyrifos Impurity 53;2-FORMYL-6-METHYLPYRIDINE
- CBNumber:
- CB2290089
- Molecular Formula:
- C7H7NO
- Molecular Weight:
- 121.14
- MDL Number:
- MFCD00006291
- MOL File:
- 1122-72-1.mol
- MSDS File:
- SDS
| Melting point | 31-33 °C(lit.) |
|---|---|
| Boiling point | 105-108°C/12mm |
| Density | 1.1344 (rough estimate) |
| refractive index |
n |
| Flash point | 155 °F |
| storage temp. | 2-8°C |
| form | Low Melting Solid |
| pka | 3.96±0.10(Predicted) |
| color | Light yellow to brown |
| Water Solubility | 750 g/L (20 ºC) |
| Sensitive | Light Sensitive/Air Sensitive |
| BRN | 107476 |
| InChI | 1S/C7H7NO/c1-6-3-2-4-7(5-9)8-6/h2-5H,1H3 |
| InChIKey | AHISYUZBWDSPQL-UHFFFAOYSA-N |
| SMILES | Cc1cccc(C=O)n1 |
| CAS DataBase Reference | 1122-72-1(CAS DataBase Reference) |
| FDA UNII | 0RNR5L79R2 |
| EPA Substance Registry System | 6-Methyl-2-pyridinecarboxaldehyde (1122-72-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | UN 1325 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-9-23 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT, LIGHT SENSITIVE, KEEP COLD | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
6-Methyl-2-pyridinecarboxaldehyde price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M78208 | 6-Methylpyridine-2-carboxaldehyde 98% | 1122-72-1 | 5g | $217 | 2026-04-30 | Buy |
| Sigma-Aldrich | M78208 | 6-Methylpyridine-2-carboxaldehyde 98% | 1122-72-1 | 25g | $1040 | 2026-04-30 | Buy |
| TCI Chemical | M1157 | 6-Methyl-2-pyridinecarboxaldehyde >98.0%(GC) | 1122-72-1 | 5g | $63 | 2026-04-30 | Buy |
| TCI Chemical | M1157 | 6-Methyl-2-pyridinecarboxaldehyde >98.0%(GC) | 1122-72-1 | 25g | $304 | 2026-04-30 | Buy |
| Usbiological | 281544 | 6-Methyl-2-pyridinecarboxaldehyde Asreported | 1122-72-1 | 2g | $366 | 2026-06-03 | Buy |
6-Methyl-2-pyridinecarboxaldehyde Chemical Properties,Uses,Production
Chemical Properties
light yellow to brown low melting solid
Uses
6-Methyl-2-pyridinecarboxaldehyde was used in the synthesis of 1-(10-cyano- and -10-bromo-5H-dibenzo[a,d]cyclohepten-5-yl)-4-[(arylmethylene)amino]piperazines which are compounds that exhibits anticon vulsant properties. 6-Methylpyridine-2-carboxaldehyde is used to produce 1-(6-methyl-pyridin-2-yl)-hexan-1-one with pent-1-ene at temperature of 100°C. This reaction will need reagent 2-amino-3-picoline and catalysts (Ph3P)3RhCl, Cp2ZrCl2.
Synthesis
1122-71-0
1122-72-1
Under stirring conditions, 10.47 g (0.081 mol) of selenite was dissolved in 30 mL of water and the resulting solution was slowly added to a 150 mL solution of 1,4-dioxane containing 20 g (0.162 mol) of 6-methyl-2-pyridinemethanol (3a). The reaction mixture was stirred continuously at 100 °C for 6 hours. Upon completion of the reaction, the resulting metallic selenium was removed by filtration. The filtrate was distilled under reduced pressure to remove the solvent and the residue was treated by extraction with hot hexane (3 x 150 mL). After combining the extracts, the solvents were again removed by distillation under reduced pressure and the resulting product did not require further purification. Finally, 14.76 g (0.121 mol, 75% yield) of 6-methyl-2-pyridinecarboxaldehyde was obtained with a melting point of 31-33 °C. The product structure was determined by 1H NMR. The structure of the product was determined by 1H NMR (DMSO-d6, δ, ppm): 2.61 (s, 3H, Me), 7.49 (d, 1H, 5-H, J = 7.5 Hz), 7.71 (d, 1H, 3-H, J = 7.5 Hz), 7.86 (dd, 1H, 4-H, J = 7.5, 7.5 Hz), 9.93 (s, 1H, CHO) and mass spectrum (m/z 122.06, I rel 100% [M + H]+) confirmed that the calculated molecular weight was 122.06.
References
[1] Tetrahedron Letters, 1999, vol. 40, # 9, p. 1635 - 1636
[2] Organometallics, 2016, vol. 35, # 10, p. 1505 - 1513
[3] Russian Journal of Organic Chemistry, 2017, vol. 53, # 7, p. 963 - 970
[4] Zh. Org. Khim., 2017, vol. 53, # 7, p. 951 - 958,8
[5] Dalton Transactions, 2012, vol. 41, # 22, p. 6661 - 6670
6-Methyl-2-pyridinecarboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuxi Hailun Bio-Technology Co., Ltd. | 0510-85629785 18051595327; | sales@hlsw-bio.com | China | 101 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Lastest Price from 6-Methyl-2-pyridinecarboxaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 6-Methyl-2-pyridinecarboxaldehyde
1122-72-1
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-07-22 | 6-Methyl-2-pyridinecarboxaldehyde
1122-72-1
|
1kg | 99% | 20MT | Watson Biotechnology Co.,Ltd | ||
 |
2026-03-20 | 6-Methyl-2-pyridinecarboxaldehyde
1122-72-1
|
$10.00 | 1KG | 99% | 5tons | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 6-Methyl-2-pyridinecarboxaldehyde
1122-72-1
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 6-Methyl-2-pyridinecarboxaldehyde
1122-72-1
- 99%
- Watson Biotechnology Co.,Ltd
-
- 6-Methyl-2-pyridinecarboxaldehyde
1122-72-1
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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