6-Methylnicotinaldehyde
- CAS No.
- 53014-84-9
- Chemical Name:
- 6-Methylnicotinaldehyde
- Synonyms
- 5-FORMYL-2-PICOLINE;6-Methylnicotinaldehyde;5-Formyl-2-methylpyridine;3-FORMYL-6-METHYL-PYRIDINE;3-Formyl-6-methyl-pyridine ,97%;6-Methylpyridine-3-carboxaldehyde;6-METHYL-3-PYRIDINECARBOXALDEHYDE;3-Pyridinecarboxaldehyde, 6-methyl-;6-Methyl-3-pyridinecarboxaldehyde>6-Methylpyridine-3-carboxaldehyde 97%
- CBNumber:
- CB0438566
- Molecular Formula:
- C7H7NO
- Molecular Weight:
- 121.14
- MDL Number:
- MFCD08272279
- MOL File:
- 53014-84-9.mol
- MSDS File:
- SDS
| Boiling point | 95℃/20mm |
|---|---|
| Density | 1.084 |
| refractive index | 1.546 |
| Flash point | 88℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 4.15±0.10(Predicted) |
| form | Liquid |
| Appearance | Colorless to light yellow Liquid |
| Sensitive | Moisture Sensitive |
| InChI | InChI=1S/C7H7NO/c1-6-2-3-7(5-9)4-8-6/h2-5H,1H3 |
| InChIKey | IMWMEIWYPWVABQ-UHFFFAOYSA-N |
| SMILES | C1=NC(C)=CC=C1C=O |
| CAS DataBase Reference | 53014-84-9 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H227-H315-H335-H302-H319 | |||||||||
| Precautionary statements | P210e-P261-P280a-P405-P501a-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 |
|||||||||
| NFPA 704 |
|
6-Methylnicotinaldehyde price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 718726 | 6-Methylpyridine-3-carboxaldehyde 97% | 53014-84-9 | 500mg | $177 | 2023-06-20 | Buy |
| TCI Chemical | M2654 | 6-Methyl-3-pyridinecarboxaldehyde >98.0%(GC) | 53014-84-9 | 200mg | $56 | 2021-12-16 | Buy |
| TCI Chemical | M2654 | 6-Methyl-3-pyridinecarboxaldehyde >98.0%(GC) | 53014-84-9 | 1g | $192 | 2021-12-16 | Buy |
| AstaTech | 24017 | 5-FORMYL-2-PICOLINE 95% | 53014-84-9 | 5G | $39 | 2026-04-30 | Buy |
| AstaTech | 24017 | 5-FORMYL-2-PICOLINE 95% | 53014-84-9 | 25G | $127 | 2026-04-30 | Buy |
6-Methylnicotinaldehyde Chemical Properties,Uses,Production
Application
3-Aldehyde-6-methylpyridine is a pyridine heterocyclic compound mainly used in laboratory research and development of organic synthesis processes.
Synthesis
To a solution of 5-bromo-2-methylpyridine (151; 10 g, 58.1 mmol) in THF (150 mL) was added n-BuLi (2.5 M, 25.6 mL) at -78 ℃. The reaction mixture was stirred at this temperature for Ih. DMF (1.30 mL) was added,, and the resulting reaction mixture was stirred for 1 h at -78 °C. The addition of aq quenched the reaction. NH4Cl. Upon warming to room temperature, the mixture was extracted with EtOAc. The combined organic layers were dried (Na2SO4) and concentrated under reduced pressure. The resulting residue was purified by chromatography to afford 6-methylnicotinaldehyde 152 (5.0 g, 72percent).
References
[1] Patent: US2006/287341, 2006, A1. Location in patent: Page/Page column 46
[2] Patent: US2007/4772, 2007, A1. Location in patent: Page/Page column 82
[3] Journal of Medicinal Chemistry, 1989, vol. 32, # 3, p. 583 - 593
[4] Journal of Organic Chemistry, 1988, vol. 53, # 15, p. 3513 - 3521
[5] Patent: US4778796, 1988, A
6-Methylnicotinaldehyde Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Yongsheng Pharmaceutical Technology Co., Ltd | 3307 18017383231 | 983544897@qq.com | China | 941 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 94607 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 28-83379370 13880556291 | tcy@tcypharm.com | China | 509 | 57 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
View Lastest Price from 6-Methylnicotinaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 3-FORMYL-6-METHYL-PYRIDINE
53014-84-9
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2026-08-13 | 6-Methylnicotinaldehyde
53014-84-9
|
1G | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2025-12-10 | 5-Formyl-2-methylpyridine
53014-84-9
|
1kg | 98% | 1000kg | Shanghai Joiny Pharmaceutical Co.,LTD |
-
- 3-FORMYL-6-METHYL-PYRIDINE
53014-84-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 6-Methylnicotinaldehyde
53014-84-9
- $0.00
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 5-Formyl-2-methylpyridine
53014-84-9
- $0.00
- 98%
- Shanghai Joiny Pharmaceutical Co.,LTD
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