Tetradifon
- CAS No.
- 116-29-0
- Chemical Name:
- Tetradifon
- Synonyms
- Sulfone;Diphenylsulfon;TCDS;V-18;Duphar;Mition;TEDION;TEDONE;tedane;Acarvin
- CBNumber:
- CB2307141
- Molecular Formula:
- C12H6Cl4O2S
- Molecular Weight:
- 356.05
- MDL Number:
- MFCD00018127
- MOL File:
- 116-29-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 146.5-147.5° |
|---|---|
| Boiling point | 484.0±45.0 °C(Predicted) |
| Density | 1.5630 (estimate) |
| storage temp. | 0-6°C |
| form | Solid |
| color | White to off-white |
| Water Solubility | 50ug/L(10 ºC) |
| Merck | 13,9273 |
| BRN | 2292528 |
| Henry's Law Constant | 6.9×103 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| Major Application |
agriculture environmental |
| InChI | 1S/C12H6Cl4O2S/c13-7-1-3-8(4-2-7)19(17,18)12-6-10(15)9(14)5-11(12)16/h1-6H |
| InChIKey | MLGCXEBRWGEOQX-UHFFFAOYSA-N |
| SMILES | Clc1ccc(cc1)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl |
| CAS DataBase Reference | 116-29-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | TIP8EA8VTS |
| NIST Chemistry Reference | P-chlorophenyl, 2,4,5-trichlorophenyl sulfone(116-29-0) |
| EPA Substance Registry System | Tetradifon (116-29-0) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H410 |
| Precautionary statements | P273-P301+P312+P330 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | WR5850000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 1 |
| Hazardous Substances Data | 116-29-0(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 556 mg/kg (Ben-dyke) |
Tetradifon price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 45680 | Tetradifon PESTANAL | 116-29-0 | 250mg | $35.2 | 2026-04-30 | Buy |
| ChemScene | CS-0077874 | Tetradifon 99.78% | 116-29-0 | 25mg | $38 | 2026-06-04 | Buy |
| ChemScene | CS-0077874 | Tetradifon 99.78% | 116-29-0 | 50mg | $60 | 2026-06-04 | Buy |
| ChemScene | CS-0077874 | Tetradifon 99.78% | 116-29-0 | 100mg | $97 | 2026-06-04 | Buy |
| ChemScene | CS-0077874 | Tetradifon 99.78% | 116-29-0 | 250mg | $195 | 2026-06-04 | Buy |
Tetradifon Chemical Properties,Uses,Production
Chemical Properties
White, crystalline powder. Soluble in chloroform and aromatic hydrocarbons; insoluble in water.
Uses
Acaricide. Ovicide on deciduous fruits, citrus, cotton and other crops.
Definition
ChEBI: A sulfone that is diphenylsulfone in which one of the phenyl groups is substituted by chlorine at position 4, while the other is substituted by a chlorine at positions 2, 4, and 5.
Production Methods
Tetradifon is produced commercially through a multi-step synthesis involving chlorinated benzene derivatives and sulfonylation reactions, resulting in a stable organochlorine acaricide used in agriculture. The process begins with the preparation of 1,2,4-trichlorobenzene, which serves as a key intermediate. This compound undergoes sulfonylation with 4-chlorobenzenesulfonyl chloride to form the active ingredient tetradifon.
Mechanism of action
Non-systemic with larvicidal and ovicidal activity. Acts by inhibiting oxidative phosphorylation. Inhibitor of mitochondrial ATP synthase.
Safety Profile
Moderately toxic by ingestion. Mildly toxic by slun contact. An experimental teratogen. Used to control worms in crops. When heated to decomposition it emits highly toxic fumes of Cland SOx.
IC 50
Mite
Pesticide Type
Acaricide; Insecticide
Tetradifon Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Chengdu Ai Keda Chemical Technology Co., Ltd. | 4008-755-333 18080918076 | 800078821@qq.com | China | 9706 | 55 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
| Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9970 | 55 |
| Chengdu RunZeBenTu Chemical Co., Ltd | 13096311329 028-88469284 616445927 | 616445927@qq.com | China | 2870 | 50 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4508 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Raw material medicin reagent co.,Ltd | sales@njromanme.com | China | 4511 | 58 | |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 9998 | 58 |
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View Lastest Price from Tetradifon manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-13 | Tetradifon
116-29-0
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-06-27 | Tetradifon
116-29-0
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2020-04-28 | Tetradifon
116-29-0
|
1KG | 99.0% | 500 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Tetradifon
116-29-0
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Tetradifon
116-29-0
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Tetradifon
116-29-0
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
