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ChemicalBook >> CAS DataBase List >>N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide Structure
N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide structure
CAS No.
1418112-77-2
Chemical Name:
N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide
Synonyms
AZD-4721;EOS-61288;Vimnerixin;Vimnerixin (AZD4721;N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide;1-Azetidinesulfonamide, N-[6-[(1R,2S)-2,3-dihydroxy-1-methylpropoxy]-2-[[(4-fluorophenyl)methyl]thio]-4-pyrimidinyl]-3-methyl-
CBNumber:
CB23143076
Molecular Formula:
C19H25FN4O5S2
Molecular Weight:
472.55
MDL Number:
MOL File:
1418112-77-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Request For Quotation

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide Properties

storage temp. Store at -20°C
form Solid
color White to off-white
FDA UNII X09ORN2BF0

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0377236 Vimnerixin 99.16% 1418112-77-2 5mg $676 2026-06-04 Buy
ChemScene CS-0377236 Vimnerixin 99.16% 1418112-77-2 10mg $1014 2026-06-04 Buy
ChemScene CS-0377236 Vimnerixin 99.16% 1418112-77-2 25mg $1825 2026-06-04 Buy
ChemScene CS-0377236 Vimnerixin 99.16% 1418112-77-2 50mg $2741 2026-06-04 Buy
ChemScene CS-0377236 Vimnerixin 99.16% 1418112-77-2 100mg $4111 2026-06-04 Buy
Product number Packaging Price Buy
CS-0377236 5mg $676 Buy
CS-0377236 10mg $1014 Buy
CS-0377236 25mg $1825 Buy
CS-0377236 50mg $2741 Buy
CS-0377236 100mg $4111 Buy

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide Chemical Properties, Uses, Production

Uses

Vimnerixin (AZD4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 (CXCR2). Vimnerixin has the potential for the research of inflammatory disease[1].

in vivo

Assessment of Pharmacokinetics (PK) profile of Vimnerixin in rat and dog[1]
.

In Vivo PKRatDog
Predicted hepatic metabolic CL (ml/min per kilogram)1.70.80
Observed CL (ml/min per kilogram)2.40.50
CLrenal (mL/min per kilogram)<0.01<0.01
CLbiliary (mL/min per kilogram)<0.010.04
In vivo/in vitro unbound CLintc1.40.6
VSS (l/kg)0.190.15
T1/2 (h) (PO)1.33.7
(2.7)(8.4)
F (%)4582

References

[1] Gardiner P, et al. Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs. Drug Metab Dispos. 2019;47(8):865-873. DOI:10.1124/dmd.119.087163

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide Suppliers

Global Suppliers ( 7)
Supplier Tel Email Country ProdList Advantage
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58
Kaixin Chemical (Hong Kong) Limited 010-88886666-01 13112345678 loyson@qq.com China 589 55
Shanghai zhigan biotechnology co., LTD zhiqianbio@126.com China 19765 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Guangzhou Ruidi Biotechnology Co., Ltd. 020-82099279 18988941402 sales@ubiochem.com China 9998 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Jinan elephant international trading co., LTD 58
Kaixin Chemical (Hong Kong) Limited 55
Shanghai zhigan biotechnology co., LTD 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
Guangzhou Ruidi Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide manufacturers

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AZD4721 pictures 2026-04-22 AZD4721
1418112-77-2
 10g TargetMol Chemicals Inc.
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1418112-77-2 (N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide) Related Search:

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide AZD-5069 BCA-1/CXCL13 Protein, MOUSE (HEK293, HIS) I-TAC/CXCL11 Protein, Mouse BL-8040
Ulocuplumab

1of2

N-(6-(((2R,3S)-3,4-dihydroxybutan-2-yl)oxy)-2-((4-fluorobenzyl)thio)pyrimidin-4-yl)-3-methylazetidine-1-sulfonamide EOS-61288 AZD-4721 1-Azetidinesulfonamide, N-[6-[(1R,2S)-2,3-dihydroxy-1-methylpropoxy]-2-[[(4-fluorophenyl)methyl]thio]-4-pyrimidinyl]-3-methyl- Vimnerixin Vimnerixin (AZD4721 1418112-77-2 C19H25FN4O5S2