ChemicalBook >> CAS DataBase List >>METHYL 2-CHLORO-5-IODONICOTINATE

METHYL 2-CHLORO-5-IODONICOTINATE

CAS No.
78686-83-6
Chemical Name:
METHYL 2-CHLORO-5-IODONICOTINATE
Synonyms
METHYL 2-CHLORO-5-IODONICOTINATE;2-Chloro-5-iodoicotinic acid methyl ester;2-Chloro-5-iodo-nicotinic acid methyl ester;Methyl 2-chloro-5-iodopyridine-3-carboxylate;Methyl 2-chloro-5-iodo-3-pyridinecarboxylate;3-Pyridinecarboxylic acid, 2-chloro-5-iodo-, methyl ester
CBNumber:
CB2314628
Molecular Formula:
C7H5ClINO2
Molecular Weight:
297.48
MDL Number:
MFCD06659607
MOL File:
78686-83-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:49
Product description Number Pack Size Price
Methyl2-chloro-5-iodonicotinate M295605 100mg $45
Methyl 2-chloro-5-iodonicotinate 454902 100mg $312
Methyl2-chloro-5-iodonicotinate 98% Y14746 5g $190
Methyl2-chloro-5-iodonicotinate 98% Y14746 1g $50
Methyl 2-chloro-5-iodonicotinate >95% 046002 500mg $77
More product size

METHYL 2-CHLORO-5-IODONICOTINATE Properties

Melting point 70-73°
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White

SAFETY

Risk and Safety Statements

HazardClass  IRRITANT
HS Code  2933399990

METHYL 2-CHLORO-5-IODONICOTINATE price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M295605 Methyl2-chloro-5-iodonicotinate 78686-83-6 100mg $45 2021-12-16 Buy
Usbiological 454902 Methyl 2-chloro-5-iodonicotinate 78686-83-6 100mg $312 2021-12-16 Buy
Frontier Specialty Chemicals Y14746 Methyl2-chloro-5-iodonicotinate 98% 78686-83-6 5g $190 2021-12-16 Buy
Frontier Specialty Chemicals Y14746 Methyl2-chloro-5-iodonicotinate 98% 78686-83-6 1g $50 2021-12-16 Buy
Matrix Scientific 046002 Methyl 2-chloro-5-iodonicotinate >95% 78686-83-6 500mg $77 2021-12-16 Buy
Product number Packaging Price Buy
M295605 100mg $45 Buy
454902 100mg $312 Buy
Y14746 5g $190 Buy
Y14746 1g $50 Buy
046002 500mg $77 Buy

METHYL 2-CHLORO-5-IODONICOTINATE Chemical Properties,Uses,Production

Synthesis

METHYL 2-HYDROXY-5-IODONICOTINATE

116387-40-7

METHYL 2-CHLORO-5-IODONICOTINATE

78686-83-6

Step 2 of Scheme 13: Methyl 5-iodo-2-hydroxynicotinate (4.75 g, 17.1 mmol) was dissolved in trichlorophosphorus (50 mL) and heated to reflux for 24 hours. After completion of the reaction, the solvent was removed by rotary evaporator. The crude product was neutralized with saturated sodium bicarbonate solution and subsequently extracted with ether. The organic phase was dried over anhydrous magnesium sulfate, filtered and concentrated by rotary evaporator. The crude product was purified by silica gel column chromatography to afford 4.3 g (85% yield) of methyl 2-chloro-5-iodonicotinate using a hexane solution of 5% ethyl acetate as eluent. The physical and chemical properties of this compound have been documented in Journal of Organic Chemistry, 1989, vol. 54.

References

[1] Patent: US2005/203081, 2005, A1. Location in patent: Page/Page column 13; 33
[2] Journal of Medicinal Chemistry, 1993, vol. 36, # 18, p. 2676 - 2688
[3] Patent: US5250548, 1993, A
[4] Patent: WO2008/76425, 2008, A1. Location in patent: Page/Page column 54
[5] Patent: WO2008/130600, 2008, A2. Location in patent: Page/Page column 46

METHYL 2-CHLORO-5-IODONICOTINATE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 78)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2972 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328 sales@dogechemical.com China 4128 58
Golden Pharma Co., Limited
+undefined18958062155 sales@zjgoldpharm.com China 5899 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58

View Lastest Price from METHYL 2-CHLORO-5-IODONICOTINATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
METHYL 2-CHLORO-5-IODONICOTINATE pictures 2024-10-22 METHYL 2-CHLORO-5-IODONICOTINATE
78686-83-6
US $1.00 / KG 1KG MIn98%HPLC/LC 100KGS Career Henan Chemica Co

METHYL 2-CHLORO-5-IODONICOTINATE Spectrum

METHYL 2-CHLORO-5-IODONICOTINATE Methyl 2-chloro-5-iodopyridine-3-carboxylate 2-Chloro-5-iodo-nicotinic acid methyl ester 2-Chloro-5-iodoicotinic acid methyl ester 3-Pyridinecarboxylic acid, 2-chloro-5-iodo-, methyl ester Methyl 2-chloro-5-iodo-3-pyridinecarboxylate 78686-83-6