2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
- CAS No.
- 37710-81-9
- Chemical Name:
- 2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
- Synonyms
- TC AQP1 1;m-Benzenediacrylic acid;TC-AQP1-1, 10 mM in DMSO;m-Phenylenediacrylic acid;TC-AQP-1-1,TCAQP11,TC AQP1 1;3,3'-(1,3-Phenylene)diacrylic acid;3,3'-(1,3-Phenylene)diacrylic acid;2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
- CBNumber:
- CB23207516
- Molecular Formula:
- C12H10O4
- Molecular Weight:
- 218.21
- MDL Number:
- MFCD00021776
- MOL File:
- 37710-81-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 458.7±33.0 °C(Predicted) |
|---|---|
| Density | 1.358±0.06 g/cm3(Predicted) |
| storage temp. | RT |
| solubility | Soluble in DMSO (up to 25 mg/ml). |
| form | solid |
| pka | 4.07±0.10(Predicted) |
| color | White |
| Stability | Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
2-Propenoic acid, 3,3'-(1,3-phenylene)bis- price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 256822 | TC AQP1 1 Asreported | 37710-81-9 | 10mg | $339 | 2026-06-03 | Buy |
| Usbiological | 256822 | TC AQP1 1 Asreported | 37710-81-9 | 50mg | $744 | 2026-06-03 | Buy |
| ChemScene | CS-0033064 | TC AQP1 1 98.03% | 37710-81-9 | 5mg | $81 | 2026-06-04 | Buy |
| ChemScene | CS-0033064 | TC AQP1 1 98.03% | 37710-81-9 | 10mg | $130 | 2026-06-04 | Buy |
| ChemScene | CS-0033064 | TC AQP1 1 98.03% | 37710-81-9 | 25mg | $260 | 2026-06-04 | Buy |
2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Chemical Properties,Uses,Production
Description
CVPA (37710-81-9) is an aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.1
Uses
TC AQP1 1 is a human aquaoporin-1 (hAQP1) selective inhibitor and is considered to have therapeutic potential towards the potential treatment of glaucoma, brain edema, inflammatory pain and certain types of cancer.
storage
Store at +4°C
References
[1] DANIEL SEELIGER. Discovery of Novel Human Aquaporin-1 Blockers[J]. ACS Chemical Biology, 2012, 8 1: 249-256. DOI:10.1021/cb300153z
2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Preparation Products And Raw materials
2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003;025-846993838003-8003 18013301590 | njduly@126.com | China | 3293 | 55 |
| Shanghai ChuangYan Chemical Technology Co., Ltd. | 021-11111111 11111111111 | 546919421@qq.com | China | 3770 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4058 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Nantong Hi-Future Biotechnology Co., Ltd | +86-0513; 18051384581 | sales@chemhifuture.com | China | 3074 | 58 |
| Hefei Mokai Pharmaceutical Technology Co., Ltd | 18130062233 | 690231469@qq.com | China | 8000 | 58 |
