ChemicalBook >> CAS DataBase List >>4-Fluoro-3-(trifluoromethyl)benzonitrile
4-Fluoro-3-(trifluoromethyl)benzonitrile
- CAS No.
- 67515-59-7
- Chemical Name:
- 4-Fluoro-3-(trifluoromethyl)benzonitrile
- Synonyms
- BUTTPARK 45\01-76;5-CYANO-2-FLUOROBENZOTRIFLUORIDE;5-cyano-2-fluorotrifluorotoluene;à,à,à,4-tetrafluoro-m-tolunitrile;4-Fluoro-3-(Trifluromethyl)Benzonitrile;4-fluoro-3-trifluoromethylphenylnitrile;4-FLUORO-3-(TRIFLUOROMETHYL)BENZONITRILE;3-(TRIFLUOROMETHYL)-4-FLUOROBENZONITRILE;4-Fluoro-3-(trifluoromethyl)benzonitrile97%;Benzonitrile, 4-fluoro-3-(trifluoromethyl)-
- CBNumber:
- CB2332958
- Molecular Formula:
- C8H3F4N
- Molecular Weight:
- 189.11
- MDL Number:
- MFCD00061284
- MOL File:
- 67515-59-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-06-04 16:00:12
| Melting point | 66 °C |
|---|---|
| Boiling point | 194°C |
| Density | 1,323 g/cm |
| Flash point | 193-195°C |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | Insoluble in water. |
| BRN | 1960344 |
| CAS DataBase Reference | 67515-59-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H312-H315-H319-H331-H335 | |||||||||
| Precautionary statements | P261-P280-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | T,Xi,Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-45-36-36/37-23-9 | |||||||||
| RIDADR | 3276 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29269090 | |||||||||
| Limited Quantities | 5.0 kg (11 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) | |||||||||
| NFPA 704 |
|
4-Fluoro-3-(trifluoromethyl)benzonitrile price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0979 | 4-Fluoro-3-(trifluoromethyl)benzonitrile >98.0%(GC) | 67515-59-7 | 5g | $31 | 2026-04-30 | Buy |
| TCI Chemical | F0979 | 4-Fluoro-3-(trifluoromethyl)benzonitrile >98.0%(GC) | 67515-59-7 | 25g | $109 | 2026-04-30 | Buy |
| Biosynth | FF64159 | 4-Fluoro-3-(trifluoromethyl)benzonitrile | 67515-59-7 | 100g | $150 | 2026-06-04 | Buy |
| Biosynth | FF64159 | 4-Fluoro-3-(trifluoromethyl)benzonitrile | 67515-59-7 | 25g | $150 | 2026-06-04 | Buy |
| Biosynth | FF64159 | 4-Fluoro-3-(trifluoromethyl)benzonitrile | 67515-59-7 | 250g | $250 | 2026-06-04 | Buy |
4-Fluoro-3-(trifluoromethyl)benzonitrile Chemical Properties,Uses,Production
Synthesis
10 mmol of 3-trifluoromethyl-4-haloaniline was dissolved in 10 mL of slightly heated glacial acetic acid. 2.5 mL of 12 mol·L⁻¹ sulfuric acid solution was slowly added and stirred until a dark yellow solution was formed. The solution was then cooled to 0–5 °C in an ice-salt bath and stirred until a white paste was formed. 10 mL of 2 mol·L⁻¹ NaNO₂ solution, cooled to 0–5 °C, was then added dropwise to the white paste under vigorous stirring (approximately 30 min) to form a reddish-brown diazonium salt solution. The solution was continued until the solution turned blue on starch-potassium iodide test paper. Finally, the glacial acetic acid was neutralized with Na₂CO₃ to pH = 7.0.
Without separation and precipitation, it was directly used for the synthesis of the target compound. 0.84 g (2 mmol) of K3[Fe(CN)6] was dissolved in 20 mL of distilled water. 4.5 mmol of ethylenediamine and 1.5 mmol of Cu(OAc)2 were added, and the mixture was stirred at room temperature for 1 h. Then, it was cooled to 0-5 °C in an ice-salt bath. The above diazonium salt solution was added dropwise to the K3[Fe(CN)6] solution (approximately 1 h), and stirred continuously for 2 h under ice-salt bath cooling, resulting in a reddish-brown precipitate. The precipitate was filtered off, the solid was washed with dichloromethane, and the organic phase was collected. The aqueous phase was extracted twice with 1/3 volume of dichloromethane, and the organic phases were collected. The two organic phases were combined, concentrated under reduced pressure, and then loaded onto a column for elution (petroleum ether:ethyl acetate = 20:1) to obtain the product.Chemical Properties
Yellow crystal
Uses
It finds it uses as a pharmaceutical intermediate.
4-Fluoro-3-(trifluoromethyl)benzonitrile Preparation Products And Raw materials
Global( 254)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 4-Fluoro-3-(trifluoromethyl)benzonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 4-Fluoro-3-(trifluoromethyl)benzonitrile
67515-59-7
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2019-07-14 | 4-Fluoro-3-(trifluoromethyl)benzonitrile
67515-59-7
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 4-Fluoro-3-(trifluoromethyl)benzonitrile
67515-59-7
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-Fluoro-3-(trifluoromethyl)benzonitrile
67515-59-7
- $1.00
- 99%
- Career Henan Chemical Co
67515-59-7(4-Fluoro-3-(trifluoromethyl)benzonitrile)Related Search:
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1of4
3-(TRIFLUOROMETHYL)-4-FLUOROBENZONITRILE
5-CYANO-2-FLUOROBENZOTRIFLUORIDE
4-FLUORO-3-(TRIFLUOROMETHYL)BENZONITRILE
BUTTPARK 45\01-76
5-Cyano-2-fluorobenzotrifluoride~alpha,alpha,alpha,4-Tetrafluoro-m-tolunitrile
4-Fluoro-3-(Trifluromethyl)Benzonitrile
4-Fluoro-3-Trifluoromethylbenzonitrile 3-Trifluoromethyl-4-fluorobenzonitrile
à,à,à,4-tetrafluoro-m-tolunitrile
4-Fluoro-3-(trifluoromethyl)benzonitrile 97%
4-Fluoro-3-(trifluoromethyl)benzonitrile97%
4-FLUORO-3-(TRIFLUOROMETHYL)BENZONITRILE, 98+%
4-Fluoro-3-(trifluromethyl)benzonitrile (5-Cyano-2-fluorobenzotrifluoride)
5-cyano-2-fluorotrifluorotoluene
3-trifluoromethyl-4-fluorophenyl-carbonitrile
4-Fluoro-3-(trifluoromethyl)benzonitrile >
Benzonitrile, 4-fluoro-3-(trifluoromethyl)-
4-fluoro-3-trifluoromethylphenylnitrile
67515-59-7
Benzotrifluoride Series
Miscellaneous
blocks
Carboxes
FluoroCompounds
Aromatic Nitriles
