SC57666
- CAS No.
- 158959-32-1
- Chemical Name:
- SC57666
- Synonyms
- SC57666;SC57666,SC-57666;SC57666, 10 mM in DMSO;Benzene, 1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-
- CBNumber:
- CB23339710
- Molecular Formula:
- C18H17FO2S
- Molecular Weight:
- 316.39
- MDL Number:
- MFCD00930301
- MOL File:
- 158959-32-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| SC57666 | IGA95932 | 5mg | $1534.85 |
| SC57666 | IGA95932 | 10mg | $2455.7 |
| SC57666 | IGA95932 | 25mg | $4604.75 |
| SC57666 | IGA95932 | 50mg | $7367.5 |
| SC57666 98.94% | CS-7166 | 1mg | $260 |
SC57666 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | IGA95932 | SC57666 | 158959-32-1 | 5mg | $1534.85 | 2026-06-04 | Buy |
| Biosynth | IGA95932 | SC57666 | 158959-32-1 | 10mg | $2455.7 | 2026-06-04 | Buy |
| Biosynth | IGA95932 | SC57666 | 158959-32-1 | 25mg | $4604.75 | 2026-06-04 | Buy |
| Biosynth | IGA95932 | SC57666 | 158959-32-1 | 50mg | $7367.5 | 2026-06-04 | Buy |
| ChemScene | CS-7166 | SC57666 98.94% | 158959-32-1 | 1mg | $260 | 2026-06-04 | Buy |
SC57666 Chemical Properties,Uses,Production
Uses
SC57666 is a selective COX2 inhibitor with an IC50 of 26 nM.
Definition
ChEBI: SC-57666 is a stilbenoid.
in vivo
SC57666 has been shown to be orally active (ED50=1.7 mpk) in the adjuvant-induced arthritis model. No gastric lesions are observed in mice after 5 h when SC57666 is administered intragastrically at 600 mpk. No intestinal damage is observed in rats after 72 h when SC57666 is administered intragastrically at 200 mpk[1].
IC 50
COX-2: 26 nM (IC50)
References
[1] Reitz DB, et al. Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally activeCOX2 inhibitors. J Med Chem. 1994 Nov 11;37(23):3878-81. DOI:10.1021/jm00049a005
[2] Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX2 inhibitor. Br J Pharmacol. 1997 May;121(1):105-17. DOI:10.1038/sj.bjp.0701076
SC57666 Preparation Products And Raw materials
Raw materials
Preparation Products
SC57666 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10318 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4991 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24957 | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q | meishipharma@126.com | China | 20033 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11972 | 58 |
