Azido-PEG3-methyl ester
- CAS No.
- 2086689-07-6
- Chemical Name:
- Azido-PEG3-methyl ester
- Synonyms
- N3-PEG3-COOMe;Azido-PEG3-methyl ester;methyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate;Methyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate , Azido-PEG3-methyl ester
- CBNumber:
- CB43373567
- Molecular Formula:
- C10H19N3O5
- Molecular Weight:
- 261.28
- MDL Number:
- MFCD30723268
- MOL File:
- 2086689-07-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P305+P351+P338 |
Azido-PEG3-methyl ester price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0114479 | Azido-PEG3-methyl ester ≥98% | 2086689-07-6 | 100mg | $163 | 2026-06-04 | Buy |
| ChemScene | CS-0114479 | Azido-PEG3-methyl ester ≥98% | 2086689-07-6 | 250mg | $356 | 2026-06-04 | Buy |
| ChemScene | CS-0114479 | Azido-PEG3-methyl ester ≥98% | 2086689-07-6 | 1g | $912 | 2026-06-04 | Buy |
| BroadPharm | bp-23517 | Azido-PEG3-methyl ester 98% | 2086689-07-6 | 100MG | $320 | 2026-05-24 | Buy |
| BroadPharm | bp-23517 | Azido-PEG3-methyl ester 98% | 2086689-07-6 | 250MG | $450 | 2026-05-24 | Buy |
Azido-PEG3-methyl ester Chemical Properties,Uses,Production
Description
Azido-PEG3-methyl ester is a click chemistry reagent with an azide(N3) and methyl ester moieties. The azide group can react with alkynes in copper-free Click Chemistry reactions. Methyl ester can be hydrolyzed under strong basic condition. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
Uses
Azido-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-methyl ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG3-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG3-methyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd | 0431-80534353 19917294565 | et@chemextension.com | China | 3904 | 55 |
| Borenpharm Co., Ltd | 027-65563561 | sales@borenpharm.com | China | 1245 | 55 |
| Zhengzhou Huiju Chemical Co., Ltd. | 0371-55900031 18137872243 | 3927209986@qq.com | China | 9997 | 55 |
| SHANGHAI FDC-CHEMICAL CO.,LTD | 021-61469567 13774476675 | sales@fdc-chemical.com | China | 10000 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 13892832556 | 2440688701@qq.com | China | 1977 | 58 |
| Changsha Bono New Materials Technology Co., Ltd. | 18191076804 | asherw9@hotmail.com | China | 2373 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 770406999@qq.com | China | 9949 | 58 |
