ChemicalBook >> CAS DataBase List >>3-AMINO-2-CYCLOHEXEN-1-ONE

3-AMINO-2-CYCLOHEXEN-1-ONE

CAS No.
5220-49-5
Chemical Name:
3-AMINO-2-CYCLOHEXEN-1-ONE
Synonyms
3-AMINOCYCLOHEX-2-EN-1-ONE;3-AMINO-CYCLOHEX-2-ENONE;AKOS 91521;Cartier impurity 10;3-aminocyclohexenone;Carteolol Impurity 25;3-Amino-2-cyclohexenone;1-Aminocyclohexene-3-one;1-Amino-1-cydohexene-3-one;3-AMINO-2-CYCLOHEXEN-1-ONE
CBNumber:
CB2342890
Molecular Formula:
C6H9NO
Molecular Weight:
111.14
MDL Number:
MFCD00013783
MOL File:
5220-49-5.mol
MSDS File:
SDS
Last updated:2026-05-28 00:18:38
Product description Number Pack Size Price
3-Amino-2-cyclohexen-1-one 99% 239372 5g $53.4
3-Amino-2-cyclohexen-1-one 99% 239372 25g $157
3-Amino-2-cyclohexen-1-one >98.0%(GC) A1936 5g $114
3-Amino-2-cyclohexen-1-one >98.0%(GC) A1936 25g $338
3-Amino-2-cyclohexen-1-one FA33721 25g $250
More product size

3-AMINO-2-CYCLOHEXEN-1-ONE Properties

Melting point 129-133 °C (lit.)
Boiling point 212.4±30.0 °C(Predicted)
Density 1.091±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility soluble in Methanol
form powder to crystal
pka 5.65±0.20(Predicted)
color Light yellow to Brown to Dark green
BRN 471354
InChI InChI=1S/C6H9NO/c7-5-2-1-3-6(8)4-5/h4H,1-3,7H2
InChIKey ZZMRPOAHZITKBV-UHFFFAOYSA-N
SMILES C1(=O)CCCC(N)=C1
CAS DataBase Reference 5220-49-5(CAS DataBase Reference)
FDA UNII V596547ZKE
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338-P280a-P304+P340-P405-P501a
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
4.6
Hazard Note  Irritant
HS Code  29223990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

3-AMINO-2-CYCLOHEXEN-1-ONE price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 239372 3-Amino-2-cyclohexen-1-one 99% 5220-49-5 5g $53.4 2023-06-20 Buy
Sigma-Aldrich 239372 3-Amino-2-cyclohexen-1-one 99% 5220-49-5 25g $157 2023-06-20 Buy
TCI Chemical A1936 3-Amino-2-cyclohexen-1-one >98.0%(GC) 5220-49-5 5g $114 2026-04-30 Buy
TCI Chemical A1936 3-Amino-2-cyclohexen-1-one >98.0%(GC) 5220-49-5 25g $338 2026-04-30 Buy
Biosynth FA33721 3-Amino-2-cyclohexen-1-one 5220-49-5 25g $250 2026-06-04 Buy
Product number Packaging Price Buy
239372 5g $53.4 Buy
239372 25g $157 Buy
A1936 5g $114 Buy
A1936 25g $338 Buy
FA33721 25g $250 Buy

3-AMINO-2-CYCLOHEXEN-1-ONE Chemical Properties,Uses,Production

Chemical Properties

Dark yellow crystal

Uses

3-Amino-2-cyclohexen-1-one was used in the synthesis of a series of 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitriles.

Synthesis

1,3-Cyclohexanedione

504-02-9

3-AMINO-2-CYCLOHEXEN-1-ONE

5220-49-5

General procedure for the synthesis of 3-amino-2-cyclohexen-1-one from 1,3-cyclohexanedione: 1,3-cyclohexanedione (0.03 mol) and ammonium acetate (0.039 mol) were added to a 100 mL three-necked flask, and the mixture was thoroughly stirred. The mixture was placed in an oil bath at 110°C for 15 min of reaction. Upon completion of the reaction, the oil bath was removed and the reaction system was allowed to cool naturally, at which time the reaction solution gradually solidified. After cooling to room temperature, ethyl acetate (10 mL) was added to the reaction mixture and heated to dissolve the solid, which was subsequently cooled to 0°C to promote crystallization. The precipitated solid was collected by filtration and dried to give yellow crystals of 3-amino-2-cyclohexen-1-one in 93.6% yield.

References

[1] New Journal of Chemistry, 2005, vol. 29, # 6, p. 769 - 772
[2] Patent: CN107337639, 2017, A. Location in patent: Paragraph 0120; 0123; 0135; 0144-0146; 0157; 0168; 0179
[3] Synlett, 2009, # 5, p. 818 - 822
[4] Synthetic Communications, 1998, vol. 28, # 7, p. 1197 - 1200
[5] Tetrahedron, 2003, vol. 59, # 43, p. 8589 - 8595

504-02-9
5220-49-5
Synthesis of 3-AMINO-2-CYCLOHEXEN-1-ONE from 1,3-Cyclohexanedione
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View Lastest Price from 3-AMINO-2-CYCLOHEXEN-1-ONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Aminocyclohex-2-en-1-one pictures 2025-04-04 3-Aminocyclohex-2-en-1-one
5220-49-5
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
3-Aminocyclohex-2-enone pictures 2024-04-12 3-Aminocyclohex-2-enone
5220-49-5
$590.00 1Kg 98 500 Kg R&D Scientific Inc.
3-aminocyclohex-2-enone pictures 2022-01-04 3-aminocyclohex-2-enone
5220-49-5
1g 98%min 100kgs/month Shanghai Rlavie Technology Co ltd
3-Amino-2-cyclohexen-1-one, 99%,96% 3-aminocyclohexenone 1-Amino-3-oxocyclohex-1-ene 1-Aminocyclohexene-3-one 3-Amino-2-cyclohexen-1-one, 98% (dry wt.), may cont. up to 5% water 1-Amino-1-cydohexene-3-one 3-Amino-2-cyclohexen-1-one 99% 3-AMINO-2-CYCLOHEXEN-1-ONE AKOS 91521 2-Cyclohexen-1-one,3-amino- 3-Amino-2-Cyclohexen-1-Ketone 3-Amino-2-cyclohexen-1-one hydrate 3-Amino-2-cyclohexen-1-one hemihydrate, 98% 3-AMINO-2-CYCLOHEXENE-1-ONE 3-Aminocyclohex-2-en-1-one 98% 3-AMINO-2-CYCLOHEXEN-1-ONE HYDRATE , CA 3-5% WATER 3-Amino-2-cyclohexen-1-one hydrate, 98%, ca 3-5% water 3-AMINO-2-CYCLOHEXENE-1-KETONE 3-Amino-2-cyclohexen-1-one > 3-Amino-2-cyclohexenone Carteolol Impurity 25 Cartier impurity 10 3-AMINOCYCLOHEX-2-EN-1-ONE 3-AMINO-CYCLOHEX-2-ENONE 5220-49-5 5520-49-5 H2NC6H7O C6H9NOxH2O AMINE Organic Building Blocks Ketones Building Blocks Carbonyl Compounds C3 to C6 Building Blocks C3 to C6 Carbonyl Compounds Chemical Synthesis Organic Building Blocks Carbonyl Compounds Ketones pharmacetical C3 to C6