3-AMINO-2-CYCLOHEXEN-1-ONE
- CAS No.
- 5220-49-5
- Chemical Name:
- 3-AMINO-2-CYCLOHEXEN-1-ONE
- Synonyms
- 3-AMINOCYCLOHEX-2-EN-1-ONE;3-AMINO-CYCLOHEX-2-ENONE;AKOS 91521;Cartier impurity 10;3-aminocyclohexenone;Carteolol Impurity 25;3-Amino-2-cyclohexenone;1-Aminocyclohexene-3-one;1-Amino-1-cydohexene-3-one;3-AMINO-2-CYCLOHEXEN-1-ONE
- CBNumber:
- CB2342890
- Molecular Formula:
- C6H9NO
- Molecular Weight:
- 111.14
- MDL Number:
- MFCD00013783
- MOL File:
- 5220-49-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Amino-2-cyclohexen-1-one 99% | 239372 | 5g | $53.4 |
| 3-Amino-2-cyclohexen-1-one 99% | 239372 | 25g | $157 |
| 3-Amino-2-cyclohexen-1-one >98.0%(GC) | A1936 | 5g | $114 |
| 3-Amino-2-cyclohexen-1-one >98.0%(GC) | A1936 | 25g | $338 |
| 3-Amino-2-cyclohexen-1-one | FA33721 | 25g | $250 |
| More product size | |||
| Melting point | 129-133 °C (lit.) |
|---|---|
| Boiling point | 212.4±30.0 °C(Predicted) |
| Density | 1.091±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 5.65±0.20(Predicted) |
| color | Light yellow to Brown to Dark green |
| BRN | 471354 |
| InChI | InChI=1S/C6H9NO/c7-5-2-1-3-6(8)4-5/h4H,1-3,7H2 |
| InChIKey | ZZMRPOAHZITKBV-UHFFFAOYSA-N |
| SMILES | C1(=O)CCCC(N)=C1 |
| CAS DataBase Reference | 5220-49-5(CAS DataBase Reference) |
| FDA UNII | V596547ZKE |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P305+P351+P338-P280a-P304+P340-P405-P501a | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 4.6 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29223990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
3-AMINO-2-CYCLOHEXEN-1-ONE price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 239372 | 3-Amino-2-cyclohexen-1-one 99% | 5220-49-5 | 5g | $53.4 | 2023-06-20 | Buy |
| Sigma-Aldrich | 239372 | 3-Amino-2-cyclohexen-1-one 99% | 5220-49-5 | 25g | $157 | 2023-06-20 | Buy |
| TCI Chemical | A1936 | 3-Amino-2-cyclohexen-1-one >98.0%(GC) | 5220-49-5 | 5g | $114 | 2026-04-30 | Buy |
| TCI Chemical | A1936 | 3-Amino-2-cyclohexen-1-one >98.0%(GC) | 5220-49-5 | 25g | $338 | 2026-04-30 | Buy |
| Biosynth | FA33721 | 3-Amino-2-cyclohexen-1-one | 5220-49-5 | 25g | $250 | 2026-06-04 | Buy |
3-AMINO-2-CYCLOHEXEN-1-ONE Chemical Properties,Uses,Production
Chemical Properties
Dark yellow crystal
Uses
3-Amino-2-cyclohexen-1-one was used in the synthesis of a series of 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitriles.
Synthesis
504-02-9
5220-49-5
General procedure for the synthesis of 3-amino-2-cyclohexen-1-one from 1,3-cyclohexanedione: 1,3-cyclohexanedione (0.03 mol) and ammonium acetate (0.039 mol) were added to a 100 mL three-necked flask, and the mixture was thoroughly stirred. The mixture was placed in an oil bath at 110°C for 15 min of reaction. Upon completion of the reaction, the oil bath was removed and the reaction system was allowed to cool naturally, at which time the reaction solution gradually solidified. After cooling to room temperature, ethyl acetate (10 mL) was added to the reaction mixture and heated to dissolve the solid, which was subsequently cooled to 0°C to promote crystallization. The precipitated solid was collected by filtration and dried to give yellow crystals of 3-amino-2-cyclohexen-1-one in 93.6% yield.
References
[1] New Journal of Chemistry, 2005, vol. 29, # 6, p. 769 - 772
[2] Patent: CN107337639, 2017, A. Location in patent: Paragraph 0120; 0123; 0135; 0144-0146; 0157; 0168; 0179
[3] Synlett, 2009, # 5, p. 818 - 822
[4] Synthetic Communications, 1998, vol. 28, # 7, p. 1197 - 1200
[5] Tetrahedron, 2003, vol. 59, # 43, p. 8589 - 8595
3-AMINO-2-CYCLOHEXEN-1-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3991 | 58 |
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +8617717059219 | sales@rlavie.com | China | 1030 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
View Lastest Price from 3-AMINO-2-CYCLOHEXEN-1-ONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-04-04 | 3-Aminocyclohex-2-en-1-one
5220-49-5
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd.
|
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2024-04-12 | 3-Aminocyclohex-2-enone
5220-49-5
|
$590.00 | 1Kg | 98 | 500 Kg | R&D Scientific Inc. | |
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2022-01-04 | 3-aminocyclohex-2-enone
5220-49-5
|
1g | 98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd |
-

- 3-Aminocyclohex-2-en-1-one
5220-49-5
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-

- 3-Aminocyclohex-2-enone
5220-49-5
- $590.00
- 98
- R&D Scientific Inc.
-

- 3-aminocyclohex-2-enone
5220-49-5
- 98%min
- Shanghai Rlavie Technology Co ltd
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