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(R)-(+)-WARFARIN

(R)-(+)-WARFARIN structure

CAS No.: 5543-58-8

Chemical Name:: (R)-(+)-WARFARIN

Synonyms: (R)-WARFARIN;Dextrowarfarin;(R)-(+)-WARFARIN;Warfarin R-Isomer;Warfarin Impurity 16;R-(+)-Warfarin >,99;Warfarin Impurity 16（Warfarin R-Isomer）;r-(+)-3-acetonybenzyl)-4-hydroxycoumarin;R-(+)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN;(S)-3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin

CBNumber:: CB2351124

Molecular Formula:: C19H16O4

Molecular Weight:: 308.33

MDL Number:: MFCD00272376

MOL File:: 5543-58-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:18:28

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(R)-(+)-WARFARIN Properties

Melting point	≥170 °C
Boiling point	515.2±50.0 °C(Predicted)
Density	1.307±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMF: soluble
pka	4.50±1.00(Predicted)
form	A crystalline solid
color	white to pale yellow
InChI	1S/C19H16O4/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22/h2-10,15,21H,11H2,1H3/t15-/m1/s1
InChIKey	PJVWKTKQMONHTI-OAHLLOKOSA-N
SMILES	[H][C@@](CC(C)=O)(c1ccccc1)C2=C(O)c3ccccc3OC2=O
FDA UNII	09CC5J5C8A
UNSPSC Code	12161501

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08,GHS09

Signal word

Danger

Hazard statements

H300+H310+H330-H360D-H372-H411

Precautionary statements

P202-P264-P273-P280-P302+P352+P310-P304+P340+P310

target organs

Blood

Hazard Codes

Risk Statements

61-48/25-52/53

Safety Statements

53-45-61

RIDADR

UN 2811 6.1/PG 1

WGK Germany

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials

Hazard Classifications

Acute Tox. 1 Dermal
Acute Tox. 1 Inhalation
Acute Tox. 2 Oral
Aquatic Chronic 2
Repr. 1A
STOT RE 1

NFPA 704

	0
4		0

(R)-(+)-WARFARIN price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	UC213	(R)-(+)-Warfarin ≥97% (HPLC)	5543-58-8	10mg	$1520	2022-05-15	Buy
Cayman Chemical	13526	(+)-Warfarin ≥98%	5543-58-8	1mg	$85	2026-04-30	Buy
Cayman Chemical	13526	(+)-Warfarin ≥98%	5543-58-8	5mg	$233	2026-04-30	Buy
Cayman Chemical	13526	(+)-Warfarin ≥98%	5543-58-8	10mg	$422	2026-04-30	Buy
Cayman Chemical	13526	(+)-Warfarin ≥98%	5543-58-8	25mg	$948	2026-04-30	Buy

Product number	Packaging	Price	Buy
UC213	10mg	$1520	Buy
13526	1mg	$85	Buy
13526	5mg	$233	Buy
13526	10mg	$422	Buy
13526	25mg	$948	Buy

(R)-(+)-WARFARIN Chemical Properties, Uses, Production

Chemical Properties

White Solid

Uses

(R)-(+)-warfarin has been used to investigate whether enantiomers of warfarin stereoselectively interact with pregnane X nuclear receptor (PXR) to upregulate main drug/xenobiotic-metabolizing enzymes cytochrome P450 3A4 (CYP3A4) and cytochrome P450 2C9 (CYP2C9). It has also been used in HepG2 cells to study protein profiles

Uses

The R-(+)-form of Warfarin (W498500). Coumarin anticoagulant.

Definition

ChEBI: (R)-warfarin is a 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one that has (R)-configuration (the racemate is warfarin, an anticoagulant drug and rodenticide). It is a conjugate acid of a (R)-warfarin(1-). It is an enantiomer of a (S)-warfarin.

General Description

The chiral carbon at position 9 produces two enantiomers, R- and S-warfarin. Commercially available warfarin (Coumadin or Jantoven) is a racemic mixture of S- and R-enantiomers.

Biochem/physiol Actions

Warfarin acts as a vitamin K antagonist. It is widely used to treat thromboembolic disorders. (R)-warfarin interacts with pregnane X receptor (PXR) and induces cytochrome P450 3A4 (CYP3A4) and CYP2C9 mRNAs expression in primary human hepatocyte cultures.

(R)-(+)-WARFARIN Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-(+)-WARFARIN Suppliers

Global Suppliers ( 73)

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7909	65
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9656	58
Cato Research Chemicals Inc.	020-81960175	min.he@cato-chem.com	China	1949	55
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9883	50
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51389	80
Nanjing XiZe Biotechnology CO., Ltd.	025-66023220 15250997978	1511893459@qq.com	China	4777	55
Artis Biotech Co. Ltd.	18108108965 18108108965	sales@artisbio.com	China	2503	58
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
Daicel Chiral Technologies (China)CO.,LTD	65
Clearsynth Labs Limited	58
Cato Research Chemicals Inc.	55
Shanghai Kewel Chemical Co., Ltd.	50
Sigma-Aldrich	80
Nanjing XiZe Biotechnology CO., Ltd.	55
Artis Biotech Co. Ltd.	58
Shanghai YuanYe Biotechnology Co., Ltd.	60

View Latest Price from (R)-(+)-WARFARIN manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-06-30	(R)-(+)-WARFARIN 5543-58-8		1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

(R)-(+)-WARFARIN
5543-58-8
$0.00
99%
Shaanxi Dideu New Materials Co. Ltd

5543-58-8 ((R)-(+)-WARFARIN) Related Search:

Warfarin 4-Hydroxycoumarin 4,4'-(Disulfanediyl)bis(2,6-di-tert-butylphenol) (S)-8-Hydroxy Warfarin (R)-6-Hydroxy Warfarin

3-(o-Hydroxyphenyl)-5-phenyl-2-cyclohexen-1-one Benzalacetone 3-[α-(2-Hydroxypropyl)benzyl]-4-hydroxycouMarin (R)-7-Hydroxy Warfarin (S)-6-Hydroxy Warfarin

Warfarin Impurity 1 2,6-Di-tert-butyl-4-mercaptophenol (S)-(-)-WARFARIN,(S)-WARFARIN 6-Hydroxywarfarin 7-Hydroxywarfarin

7-Hydroxywarfarin 8-Hydroxywarfarin (R)-8-Hydroxy warfarin

1of4

4-Hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one (R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone (S)-3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin r-(+)-3-acetonybenzyl)-4-hydroxycoumarin 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, (R)- 2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]- (9CI) Coumarin, 3-(a-acetonylbenzyl)-4-hydroxy-, R-(+)- (8CI) Dextrowarfarin R-(+)-3-Acetonybenzyl)-4-hydroxycoumarin, R-(+)-4-Hydroxy-3-(3-oxo-1-phenybutyl)-2H-1-benzopyran-2-one (+)-3-[(R)-1-Phenyl-3-oxobutyl]-4-hydroxycoumarin (+)-3-[(R)-α-Acetonylbenzyl]-4-hydroxycoumarin (+)-4-Hydroxy-3-[(R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one 2-hydroxy-3-[(1R)-3-keto-1-phenyl-butyl]chromone 2-hydroxy-3-[(1R)-3-oxo-1-phenyl-butyl]chromen-4-one 2-hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]chromen-4-one Warfarin R-Isomer R-(+)-4-HYDROXY-3-(3-OXO-1-PHENYBUTYL)-2H-1-BENZOPYRAN-2-ONE (R)-(+)-4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)-2H-1-BENZOPYRAN-2-ONE R-(+)-3-(ACETONYLBENZYL)-4-HYDROXYCOUMARIN (R)-(+)-WARFARIN 2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1R)-3-oxo-1-phenylbutyl]- Warfarin Impurity 16（Warfarin R-Isomer） Warfarin Impurity 16 (R)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one (R)-(+)-WarfarinQ: What is (R)-(+)-Warfarin Q: What is the CAS Number of (R)-(+)-Warfarin Q: What is the storage condition of (R)-(+)-Warfarin R-(+)-Warfarin >,99 (R)-WARFARIN 4-Hydroxy-3-[3-oxo-1(R)-phenylbutyl]-2H-1-benzopyran-2-one 5543-58-8 Aromatics Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals