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ChemicalBook >> CAS DataBase List >>N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide

N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide

N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide Structure
N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide structure
CAS No.
371116-39-1
Chemical Name:
N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide
Synonyms
Progranulin modulator-3;2-Furancarboxamide, N-(2-phenyl-5-benzoxazolyl)-;N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide
CBNumber:
CB23534470
Molecular Formula:
C18H12N2O3
Molecular Weight:
304.3
MDL Number:
MFCD02625038
MOL File:
371116-39-1.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:55
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N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide Properties

Boiling point 385.7±17.0 °C(Predicted)
Density 1.343±0.06 g/cm3(Predicted)
form Solid
pka 11.35±0.43(Predicted)
color Off-white to light yellow

N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1176659 Progranulin modulator-3 99.95% 371116-39-1 5mg $119 2026-06-04 Buy
ChemScene CS-1176659 Progranulin modulator-3 99.95% 371116-39-1 10mg $195 2026-06-04 Buy
ChemScene CS-1176659 Progranulin modulator-3 99.95% 371116-39-1 25mg $406 2026-06-04 Buy
ChemScene CS-1176659 Progranulin modulator-3 99.95% 371116-39-1 50mg $650 2026-06-04 Buy
aablocks AA02RJEY N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide >98% 371116-39-1 5mg $158 2026-06-03 Buy
Product number Packaging Price Buy
CS-1176659 5mg $119 Buy
CS-1176659 10mg $195 Buy
CS-1176659 25mg $406 Buy
CS-1176659 50mg $650 Buy
AA02RJEY 5mg $158 Buy

N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide Chemical Properties, Uses, Production

Uses

Progranulin modulator-3 (compd C40) is a brain-penetrant and orally active progranulin (PGRN) inducer. Progranulin modulator-3 can be used for neurological research[1].

in vivo

Progranulin modulator-3 (10 mg/kg, i.p., 24h) shows a half life of 41 min and Cmaxs of 1498 ng/mL and 6246 ng/g in mice plasma and brain, respectively, and increases PGRN protein levels in Grn+/ mouse brains[1].

References

[1] Tesla R, et al. Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency. Nat Commun. 2024 Jul 20;15(1):6125. DOI:10.1038/s41467-024-50076-8

N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 5000 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
Jinan Jiuli Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

371116-39-1 (N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide) Related Search:

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N-(2-phenyl-1,3-benzoxazol-5-yl)furan-2-carboxamide 2-Furancarboxamide, N-(2-phenyl-5-benzoxazolyl)- Progranulin modulator-3 371116-39-1