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(3-Bromophenyl)acetic acid methyl ester

(3-Bromophenyl)acetic acid methyl ester Structure
(3-Bromophenyl)acetic acid methyl ester structure
CAS No.
150529-73-0
Chemical Name:
(3-Bromophenyl)acetic acid methyl ester
Synonyms
METHYL 2-(3-BROMOPHENYL)ACETATE;Methyl 3-bromophenylacetate;Methyl3-bromophenylacetate98%;Methyl 3-bromophenylacetate 98%;methyl 2-(3-bromophenyl)acetatee;Methyl 2-(3-bromophenyl)acetate, 97%;(3-Bromophenyl)acetic acid methyl ester;Benzeneacetic acid, 3-bromo-, methyl ester;3-Bromophenylacetic acid methyl ester, Methyl 2-(3-bromophenyl)ethanoate
CBNumber:
CB2357050
Molecular Formula:
C9H9BrO2
Molecular Weight:
229.07
MDL Number:
MFCD06858764
MOL File:
150529-73-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:50:38
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(3-Bromophenyl)acetic acid methyl ester Properties

Boiling point 268.6±15.0 °C(Predicted)
Density 1.445±0.06 g/cm3(Predicted)
refractive index 1.5440 to 1.5480
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Colorless to Almost colorless

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xi
Hazard Note  Harmful/Irritant/Keep Cold
HS Code  2916399090
NFPA 704
1
0 0

(3-Bromophenyl)acetic acid methyl ester price More Price(60)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M2804 Methyl 3-Bromophenylacetate >98.0%(GC) 150529-73-0 5g $66 2026-04-30 Buy
TCI Chemical M2804 Methyl 3-Bromophenylacetate >98.0%(GC) 150529-73-0 25g $196 2026-04-30 Buy
Biosynth FM46201 Methyl 2-(3-bromophenyl)acetate 150529-73-0 50g $900 2026-06-04 Buy
Biosynth FM46201 Methyl 2-(3-bromophenyl)acetate 150529-73-0 500g $900 2026-06-04 Buy
Biosynth FM46201 Methyl 2-(3-bromophenyl)acetate 150529-73-0 25g $900 2026-06-04 Buy
Product number Packaging Price Buy
M2804 5g $66 Buy
M2804 25g $196 Buy
FM46201 50g $900 Buy
FM46201 500g $900 Buy
FM46201 25g $900 Buy

(3-Bromophenyl)acetic acid methyl ester Chemical Properties, Uses, Production

Uses

Methyl 2-(3-bromophenyl)acetate is used as a reagent to synthesize the methyl ester derivative of (R)-Flurbiprofen (F598730). (R)-Flurbiprofen is a nonsteroidal anti-inflammatory drug that exists as a racemate and also has potential application as a treatment for patients with Alzheimer’s Disease.

Synthesis

Methanol

67-56-1

3-Bromophenylacetic acid

1878-67-7

(3-BROMOPHENYL)ACETIC ACID METHYL ESTER

150529-73-0

General procedure for the synthesis of methyl (3-bromophenyl)acetate from methanol and 3-bromophenylacetic acid: acetyl chloride (0.08 mL, 1.2 mmol, 0.5 eq.) and 3-bromophenylacetic acid (0.5 g, 2.3 mmol, 1.0 eq.) were added to methanol (10 mL), and the reaction mixture was refluxed for 2 hours. Upon completion of the reaction, the consumption of starting material was confirmed by TLC monitoring. The reaction mixture was concentrated and extracted with dichloromethane (DCM). The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford methyl (3-bromophenyl)acetate as a colorless oil (0.525 g, 98.7% yield). The product was analyzed by LC-MS (ES), m/z = 229.0, 231.0 [M + H]+. 1H NMR (400 MHz, DMSO-d6) δ 3.61 (s, 3H), 3.70 (s, 2H), 7.26-7.30 (m, 2H), 7.43-7.46 (m, 1H), 7.48 (s, 1H).

References

[1] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2843 - 2866
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 3, p. 392 - 395
[3] Patent: EP1479681, 2004, A1. Location in patent: Page 111; 112
[4] Patent: US2007/3539, 2007, A1. Location in patent: Page/Page column 96
[5] Journal of Medicinal Chemistry, 1995, vol. 38, # 26, p. 4976 - 4984

(3-Bromophenyl)acetic acid methyl ester Preparation Products And Raw materials

Raw materials

3-Bromophenylacetic acid Methanol 3-Bromo-phenyl acetate

Preparation Products

Methyl 1-(3-broMophenyl)cyclopropane-1-carboxylate 3-Biphenyl-3',4'-difluoro-acetic acid 2-(3-bromophenyl)-2,2-difluoroacetic acid 3-Biphenyl-3',5'-difluoro-acetic acid

(3-Bromophenyl)acetic acid methyl ester Suppliers

Global Suppliers ( 161)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Supplier Advantage
J & K SCIENTIFIC LTD. 76
TAIYUAN RHF CO.,LTD. 56
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Beijing Ouhe Technology Co., Ltd 60
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Pure Chemistry Scientific Inc. 62
Tetranov Biopharm 64
Accela ChemBio Co.,Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64

View Latest Price from (3-Bromophenyl)acetic acid methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(3-BROMOPHENYL)ACETIC ACID METHYL ESTER pictures 2020-01-03 (3-BROMOPHENYL)ACETIC ACID METHYL ESTER
150529-73-0
 $1.00 1KG 99% 10000KGS Career Henan Chemical Co

(3-Bromophenyl)acetic acid methyl ester Spectrum

(3-BROMOPHENYL)ACETIC ACID METHYL ESTER(150529-73-0)1HNMR(3-BROMOPHENYL)ACETIC ACID METHYL ESTER(150529-73-0)FT-IR

150529-73-0 ((3-Bromophenyl)acetic acid methyl ester) Related Search:

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Methyl 3-bromophenylacetate 98% 3-Bromophenylacetic acid methyl ester, Methyl 2-(3-bromophenyl)ethanoate Methyl3-bromophenylacetate98% methyl 2-(3-bromophenyl)acetatee Benzeneacetic acid, 3-bromo-, methyl ester Methyl 2-(3-bromophenyl)acetate, 97% METHYL 2-(3-BROMOPHENYL)ACETATE Methyl 3-bromophenylacetate (3-Bromophenyl)acetic acid methyl ester 150529-73-0 blocks Bromides Carboxes pharmacetical