Methyl 4-bromophenylacetate
- CAS No.
- 41841-16-1
- Chemical Name:
- Methyl 4-bromophenylacetate
- Synonyms
- METHYL 2-(4-BROMOPHENYL)ACETATE;NSC 245163;ASISCHEM D13381;Aprocitentan Impurity 32;METHYL 4-BROMOPHENYLACETATE;Methyl 4-bromophenylaceta...;4 - broMobenzene Methyl acetate;Methyl 4-BroMophenylacetate, 97+%;methyl 2-(4-bromophenyl)ethanoate;4-BROMOPHENYL ACETIC ACID METHYL ESTER
- CBNumber:
- CB9124541
- Molecular Formula:
- C9H9BrO2
- Molecular Weight:
- 229.07
- MDL Number:
- MFCD00126844
- MOL File:
- 41841-16-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 113-114 °C |
|---|---|
| Boiling point | 138-140 °C(Press: 13 Torr) |
| Density | 1.445±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Ethyl Acetate |
| form | Oil |
| color | Clear Colorless to Pale Yellow |
| InChI | InChI=1S/C9H9BrO2/c1-12-9(11)6-7-2-4-8(10)5-3-7/h2-5H,6H2,1H3 |
| InChIKey | QHJOWSXZDCTNQX-UHFFFAOYSA-N |
| SMILES | C1(CC(OC)=O)=CC=C(Br)C=C1 |
| CAS DataBase Reference | 41841-16-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312-H315-H319-H335 |
| Precautionary statements | P280-P301+P312-P261 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 29163990 |
| REACH Registrations | Active |
Methyl 4-bromophenylacetate price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-M294310-1G | Methyl 4-Bromophenylacetate | 41841-16-1 | 1g | $142 | 2026-06-03 | Buy |
| Activate Scientific | AS31285 | Methyl 4-bromophenylacetate 98% | 41841-16-1 | 25g | $20 | 2026-06-04 | Buy |
| Activate Scientific | AS31285 | Methyl 4-bromophenylacetate 98% | 41841-16-1 | 100g | $54 | 2026-06-04 | Buy |
| Apolloscientific | OR15214 | Methyl (4-bromophenyl)acetate 97% | 41841-16-1 | 1g | $21 | 2026-06-04 | Buy |
| AK Scientific | J93174 | Methyl 4-bromophenylacetate 95% | 41841-16-1 | 5g | $12 | 2026-06-04 | Buy |
Methyl 4-bromophenylacetate Chemical Properties, Uses, Production
Chemical Properties
Pale Yellow Oil
Uses
Methyl 4-Bromophenylacetate (cas# 41841-16-1) is a compound useful in organic synthesis.
Synthesis
67-56-1
1878-68-8
41841-16-1
Step 3: Synthesis of methyl 4-bromophenylacetate Sulfuric acid (56.5 mL) was slowly added dropwise to a solution of 206.6 g of 4-bromophenylacetic acid in methanol (800 mL), with the rate of dropwise acceleration being controlled to prevent violent exotherm. After the dropwise addition, the reaction mixture was heated to reflux and maintained at reflux for 2 hours. Subsequently, the device was replaced and the reflux condenser was replaced with a distillation header and approximately 400 mL of methanol was removed by distillation at atmospheric pressure. The reaction system was cooled down to 50 °C and the reaction was continued with stirring for 16 hours. Upon completion of the reaction, the mixture was cooled to room temperature, transferred to a dispensing funnel and partitioned with dichloromethane (1 L) and water (600 mL). The organic phase was separated, washed with saturated sodium bicarbonate solution and dried with anhydrous magnesium sulfate. The organic phase was concentrated under reduced pressure to give 220.1 g (98% yield) of methyl 4-bromophenylacetate as a colorless oil. HNMR (CDCl3): δ 3.59 (s, 2H), 3.70 (s, 3H), 7.16 (d, 2H), 7.45 (d, 2H).
References
[1] Journal of Organic Chemistry, 1994, vol. 59, # 9, p. 2620 - 2622
[2] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2843 - 2866
[3] Journal of Medicinal Chemistry, 2001, vol. 44, # 17, p. 2701 - 2706
[4] Patent: US2008/21024, 2008, A1. Location in patent: Page/Page column 80
[5] Patent: WO2010/86820, 2010, A1. Location in patent: Page/Page column 41
Methyl 4-bromophenylacetate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Longtai Pharmaceutical Technology Co., Ltd. | 512-66368267 18979547572 | 3381927217@qq.com | China | 28 | 58 |
| Changzhou Pumelo Co.,Ltd. | 0519-81698808 13809072999 | pml@pmlchem.com | China | 64 | 55 |
| LEWOO PHARMATECH (SHANGHAI) CO.,LTD | 15800805830 | miao@lewoopharma.com.cn | China | 976 | 58 |
| Jinan Dexinjia Bio&Tech Co., Ltd | 0531-82375880 15098789112 | 3845379039@qq.com | China | 1457 | 58 |
| Wuxi Nanfang Chemistry Additives Co.,Ltd. | 0510-85580939 18261593783 | nanfangchem@126.com | China | 34 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from Methyl 4-bromophenylacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-31 | methyl 2-(4-bromophenyl)acetate
41841-16-1
|
1KG | 98 | 1000 KG | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-06-27 | Methyl 4-bromophenylacetate
41841-16-1
|
1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-06-20 | Methyl 4-bromophenylacetate
41841-16-1
|
$5.00-10.00 | 1kg | 0.99 | 15 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- methyl 2-(4-bromophenyl)acetate
41841-16-1
- $0.00
- 98
- Shaanxi Dideu New Materials Co. Ltd
-
- Methyl 4-bromophenylacetate
41841-16-1
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Methyl 4-bromophenylacetate
41841-16-1
- $5.00-10.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
