Methyl 4-bromophenylacetate
- CAS No.
- 41841-16-1
- Chemical Name:
- Methyl 4-bromophenylacetate
- Synonyms
- METHYL 2-(4-BROMOPHENYL)ACETATE;NSC 245163;ASISCHEM D13381;Aprocitentan Impurity 32;METHYL 4-BROMOPHENYLACETATE;Methyl 4-bromophenylaceta...;4 - broMobenzene Methyl acetate;Methyl 4-BroMophenylacetate, 97+%;methyl 2-(4-bromophenyl)ethanoate;4-BROMOPHENYL ACETIC ACID METHYL ESTER
- CBNumber:
- CB9124541
- Molecular Formula:
- C9H9BrO2
- Molecular Weight:
- 229.07
- MDL Number:
- MFCD00126844
- MOL File:
- 41841-16-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Methyl4-Bromophenylacetate | M294310 | 10g | $375 |
| 4-BROMOPHENYL ACETIC ACID METHYL ESTER 95.00% | HCH0013002 | 1G | $671.75 |
| 4-BROMOPHENYL ACETIC ACID METHYL ESTER 95.00% | HCH0013002 | 5G | $988.33 |
| 4-BROMOPHENYL ACETIC ACID METHYL ESTER 95.00% | HCH0013002 | 10G | $1398.82 |
| Methyl 2-(4-bromophenyl)acetate 98% | P000131726 | 500g | $168 |
| More product size | |||
| Melting point | 113-114 °C |
|---|---|
| Boiling point | 138-140 °C(Press: 13 Torr) |
| Density | 1.445±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform, Ethyl Acetate |
| form | Oil |
| color | Clear Colorless to Pale Yellow |
| InChI | InChI=1S/C9H9BrO2/c1-12-9(11)6-7-2-4-8(10)5-3-7/h2-5H,6H2,1H3 |
| InChIKey | QHJOWSXZDCTNQX-UHFFFAOYSA-N |
| SMILES | C1(CC(OC)=O)=CC=C(Br)C=C1 |
| CAS DataBase Reference | 41841-16-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312-H315-H319-H335 |
| Precautionary statements | P280-P301+P312-P261 |
| Hazard Codes | Xi |
| HazardClass | IRRITANT |
| HS Code | 29163990 |
Methyl 4-bromophenylacetate price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M294310 | Methyl4-Bromophenylacetate | 41841-16-1 | 10g | $375 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0013002 | 4-BROMOPHENYL ACETIC ACID METHYL ESTER 95.00% | 41841-16-1 | 1G | $671.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0013002 | 4-BROMOPHENYL ACETIC ACID METHYL ESTER 95.00% | 41841-16-1 | 5G | $988.33 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0013002 | 4-BROMOPHENYL ACETIC ACID METHYL ESTER 95.00% | 41841-16-1 | 10G | $1398.82 | 2021-12-16 | Buy |
| Ark Pharm | P000131726 | Methyl 2-(4-bromophenyl)acetate 98% | 41841-16-1 | 500g | $168 | 2021-12-16 | Buy |
Methyl 4-bromophenylacetate Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Oil
Uses
Methyl 4-Bromophenylacetate (cas# 41841-16-1) is a compound useful in organic synthesis.
Synthesis
67-56-1
1878-68-8
41841-16-1
Step 3: Synthesis of methyl 4-bromophenylacetate Sulfuric acid (56.5 mL) was slowly added dropwise to a solution of 206.6 g of 4-bromophenylacetic acid in methanol (800 mL), with the rate of dropwise acceleration being controlled to prevent violent exotherm. After the dropwise addition, the reaction mixture was heated to reflux and maintained at reflux for 2 hours. Subsequently, the device was replaced and the reflux condenser was replaced with a distillation header and approximately 400 mL of methanol was removed by distillation at atmospheric pressure. The reaction system was cooled down to 50 °C and the reaction was continued with stirring for 16 hours. Upon completion of the reaction, the mixture was cooled to room temperature, transferred to a dispensing funnel and partitioned with dichloromethane (1 L) and water (600 mL). The organic phase was separated, washed with saturated sodium bicarbonate solution and dried with anhydrous magnesium sulfate. The organic phase was concentrated under reduced pressure to give 220.1 g (98% yield) of methyl 4-bromophenylacetate as a colorless oil. HNMR (CDCl3): δ 3.59 (s, 2H), 3.70 (s, 3H), 7.16 (d, 2H), 7.45 (d, 2H).
References
[1] Journal of Organic Chemistry, 1994, vol. 59, # 9, p. 2620 - 2622
[2] Bioorganic and Medicinal Chemistry, 2003, vol. 11, # 13, p. 2843 - 2866
[3] Journal of Medicinal Chemistry, 2001, vol. 44, # 17, p. 2701 - 2706
[4] Patent: US2008/21024, 2008, A1. Location in patent: Page/Page column 80
[5] Patent: WO2010/86820, 2010, A1. Location in patent: Page/Page column 41
Methyl 4-bromophenylacetate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Liteng Biotechnology Co. , Ltd. | +86-18663721413 +86-15552573001 | rosy@litengpharm.com | China | 3280 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13843 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2949 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88298848 | info@edengenechem.com | China | 2176 | 58 |
View Lastest Price from Methyl 4-bromophenylacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-27 | Methyl 4-bromophenylacetate
41841-16-1
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-06-20 | Methyl 4-bromophenylacetate
41841-16-1
|
US $10.00-5.00 / kg | 1kg | 0.99 | 15 tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2021-07-13 | Methyl 4-bromophenylacetate
41841-16-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Methyl 4-bromophenylacetate
41841-16-1
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Methyl 4-bromophenylacetate
41841-16-1
- US $10.00-5.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- Methyl 4-bromophenylacetate
41841-16-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
