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10,12-Tricosadiynoic acid

10,12-Tricosadiynoic acid Structure
10,12-Tricosadiynoic acid structure
CAS No.
66990-30-5
Chemical Name:
10,12-Tricosadiynoic acid
Synonyms
TIMTEC-BB SBB009036;10,12-Tricosadiynoicaci;10,12-Tricosadiynoic acid;tricosa-10,12-diynoic acid;10,12-Tricosadiynoic acid - [T94776];10,12-Tricosadiynoic acid >=98.0% (GC);10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%;10,12-Tricosadiynoic acid,ROS,mono- acylglycerol acyltransferase,10,12Tricosadiynoic acid,fatty,Diacylglycerol acyltransferase,SIRT1-AMPK,Diglyceride acyltransferase,metabolic,mitochondrial,oxidation,insulin,10,12 Tricosadiynoic acid,inhibit,triglyceride,Inhibitor,Acyltransferase,acyl-CoA:cholesterol acyltransferase,acid
CBNumber:
CB2360625
Molecular Formula:
C23H38O2
Molecular Weight:
346.55
MDL Number:
MFCD00041683
MOL File:
66990-30-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:50:38
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10,12-Tricosadiynoic acid Properties

Melting point 56-60 °C
storage temp. Refrigerator
solubility DMSO : 100 mg/mL (288.56 mM）
form Solid
color White to off-white
Water Solubility Insoluble in water.
Sensitive Light Sensitive
BRN 1880414
InChI 1S/C23H38O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23(24)25/h2-10,15-22H2,1H3,(H,24,25)
InChIKey DIEDVCMBPCRJFQ-UHFFFAOYSA-N
SMILES CCCCCCCCCCC#CC#CCCCCCCCCC(O)=O
CAS DataBase Reference 66990-30-5(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
F  10-23
HS Code  29161900
Storage Class 11 - Combustible Solids
NFPA 704
0
0 0

10,12-Tricosadiynoic acid price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 91445 10,12-Tricosadiynoic acid ≥98.0% (GC) 66990-30-5 5g $282 2026-04-30 Buy
TCI Chemical T1200 10,12-Tricosadiynoic Acid >98.0%(GC)(T) 66990-30-5 100mg $14 2021-12-16 Buy
TRC TRC-T896460-2MG 10,12-Tricosadiynoic Acid 66990-30-5 2mg $78 2026-06-03 Buy
TRC TRC-T896460-1MG 10,12-Tricosadiynoic Acid 66990-30-5 1mg $59 2026-06-03 Buy
TRC TRC-T896460-10MG 10,12-Tricosadiynoic Acid 66990-30-5 10mg $96 2026-06-03 Buy
Product number Packaging Price Buy
91445 5g $282 Buy
T1200 100mg $14 Buy
TRC-T896460-2MG 2mg $78 Buy
TRC-T896460-1MG 1mg $59 Buy
TRC-T896460-10MG 10mg $96 Buy

10,12-Tricosadiynoic acid Chemical Properties, Uses, Production

Uses

It is an active pharmaceutical intermediate.

Definition

ChEBI: 10,12-tricosadiynoic acid is a very long-chain fatty acid.

in vivo

10,12-Tricosadiynoic acid (100 μg/kg; oral gavage; daily; for 8 weeks; male Wistar rats) treatment increases hepatic mitochondrial fatty acid oxidation (FAO) via activation of the SIRT1-AMPK (adenosine 5′-monophosphate-activated protein kinase) pathway and proliferator activator receptor α and reduces hydrogen peroxide accumulation in high fat diet-fed rats, which significantly decreases hepatic lipid and ROS contents, reduces body weight gain, and decreases serum triglyceride and insulin levels[1].
10,12-Tricosadiynoic acid (0 mg/kg, 37.5 mg/kg, 75 mg/kg, and 150 mg/kg diet) treatment does not affect weight gain, but significantly decreases peroxisomal β-oxidation in the liver, and increased body fat accumulation in Nile tilapia. The fish with impaired peroxisomal β-oxidation exhibited higher contents of serum lipid and peroxidation products, and alanine aminotransferase activity, and significantly lowered hepatic activities of superoxide dismutase and catalase[3].

Animal Model:Male Wistar rats (210-230 g) fed with high fat diet[1]
Dosage:100 μg/kg
Administration:Oral gavage; daily; for 8 weeks
Result: Reduced hydrogen peroxide accumulation in high fat diet-fed rats, which significantly decreased hepatic lipid and ROS contents, reduced body weight gain, and decreased serum triglyceride and insulin levels.

10,12-Tricosadiynoic acid synthesis

2777-65-3
118869-25-3
66990-30-5
Synthesis of 10,12-Tricosadiynoic acid from 10-Undecynoic acid and Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

10,12-Tricosadiynoic acid Preparation Products And Raw materials

Raw materials

1-Dodecyne, 1-iodo- 10-Undecynoic acid

Preparation Products

10,12-Tricosadiynoic acid Suppliers

Global Suppliers ( 100)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Energy Chemical 61
Shandong Xiya Chemical Co., Ltd 57
Syntechem Co.,Ltd 57
Sichuan Kulinan Technology Co., Ltd 57
T&W GROUP 58

View Latest Price from 10,12-Tricosadiynoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
10,12-Tricosadiynoic acid pictures 2026-07-15 10,12-Tricosadiynoic acid
66990-30-5
 $41.00-91.00 99.91% 10g TargetMol Chemicals Inc.
10,12-Tricosadiynoic acid pictures 2026-07-15 10,12-Tricosadiynoic acid
66990-30-5
 $41.00-91.00 99.91% 10g TargetMol Chemicals Inc.
10,12-Tricosadiynoic acid pictures 2025-04-28 10,12-Tricosadiynoic acid
66990-30-5
 $41.00-91.00 99.91% 10g TargetMol Chemicals Inc.

10,12-Tricosadiynoic acid Spectrum

10,12-TRICOSADIYNOIC ACID(66990-30-5)1HNMR

66990-30-5 (10,12-Tricosadiynoic acid) Related Search:

Propiolic Acid 10,12-Pentacosadiynoic acid, [2-3H] Methyl 10,12-tricosadiynoate Methyl 10,12-pentacosadiynoate 10,12-Nonacosadiynoic acid
10,12-Pentacosadiynoic acid 10,12-Tricosadiynoic acid 1,2-Bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphoethanolamine 10,12-Heptacosadiynoic acid

1of2

TIMTEC-BB SBB009036 tricosa-10,12-diynoic acid 10,12-Tricosadiynoic acid >=98.0% (GC) 10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97%10,12-TRICOSADIYNOIC ACID, 97% 10,12-Tricosadiynoicaci 10,12-Tricosadiynoic acid,ROS,mono- acylglycerol acyltransferase,10,12Tricosadiynoic acid,fatty,Diacylglycerol acyltransferase,SIRT1-AMPK,Diglyceride acyltransferase,metabolic,mitochondrial,oxidation,insulin,10,12 Tricosadiynoic acid,inhibit,triglyceride,Inhibitor,Acyltransferase,acyl-CoA:cholesterol acyltransferase,acid 10,12-Tricosadiynoic acid - [T94776] 10,12-Tricosadiynoic acid 66990-30-5 6690-30-5 CH3CH29CCCCCH28CO2H CH3CH29CCCCCH28COOH Building Blocks Carboxylic Acids Carbonyl Compounds C13 to C42+ Organic Building Blocks Acetylenes Diacetylene Monocarboxylic Acids Acetylenic Carboxylic Acids & Their Derivatives LB Films Acetylenes Acetylenic Carboxylic Acids & Their Derivatives Diacetylene Monocarboxylic Acids Functional Materials LB Films