U-73343
- CAS No.
- 142878-12-4
- Chemical Name:
- U-73343
- Synonyms
- U-73343;U-73343, 10 mM in DMSO;U73343, U-73343, U 73343;U-73343, Inactive analog of U73122;U-73343 - CAS 142878-12-4 - Calbiochem;U-73343,Inhibitor,U73343,Phospholipase,inhibit;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-
- CBNumber:
- CB2377935
- Molecular Formula:
- C29H42N2O3
- Molecular Weight:
- 466.66
- MDL Number:
- MFCD00211221
- MOL File:
- 142878-12-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 641.5±55.0 °C(Predicted) |
|---|---|
| Density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | +15C to +30C |
| solubility | ethanol: 0.93 mg/mL |
| form | powder |
| pka | 10.68±0.40(Predicted) |
| color | white |
| Stability | Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting. |
| InChIKey | CJHWFIUASFBCKN-ZRJUGLEFSA-N |
| SMILES | [H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(OC)ccc24)NCCCCCCN5C(=O)CCC5=O |
| FDA UNII | S2C4J8704C |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H315-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
U-73343 price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | U6881 | U-73343 | 142878-12-4 | 1mg | $185 | 2026-04-30 | Buy |
| Sigma-Aldrich | 662041 | U-73343 | 142878-12-4 | 5mg | $161 | 2026-04-30 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 142878-12-4 | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 142878-12-4 | 5mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 142878-12-4 | 10mg | $169 | 2026-04-30 | Buy |
U-73343 Chemical Properties,Uses,Production
Description
U-73343 (142878-12-4) is a negative control for phospholipase C inhibitor U-73122 (Cat.# 10-1061).1,2 Elicits unexpected effects on rabbit parietal cells.3Cell permeable.
Uses
U-73343 is an inactive structural analog of U-73122.
General Description
A cell-permeable analog of U-73122 (Cat. No. 662035) that acts as a very weak inhibitor of phospholipase C. Suitable as a negative control.
Biochem/physiol Actions
Cell permeable: yes
storage
Store at RT
References
[1] J E BLEASDALE. Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.[J]. Journal of Pharmacology and Experimental Therapeutics, 1990, 255 2: 756-768.
[2] P MORLEY. A new, nongenomic estrogen action: the rapid release of intracellular calcium.[J]. Endocrinology, 1992, 131 3: 1305-1312. DOI:10.1210/endo.131.3.1505465
[3] Y MUTO T U T Nagao. The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell.[J]. Journal of Pharmacology and Experimental Therapeutics, 1997, 282 3: 1379-1388.
U-73343 Preparation Products And Raw materials
Raw materials
Preparation Products
U-73343 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 | sales@sun-shinechem.com | China | 1197 | 64 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Anhui kuer Bioengineering Co., Ltd | 0551-65171243 13856024262 | kuer@kuerhuaxue.com | China | 2996 | 55 |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 9998 | 58 | |
| Shanghai BetterBioChem Co., Ltd. | +86-18017644823 | sales@betterbiochem.com | China | 324 | 58 |
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