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2-Amino-4-methoxypyridine

2-Amino-4-methoxypyridine structure

CAS No.: 10201-73-7

Chemical Name:: 2-Amino-4-methoxypyridine

Synonyms: 4-METHOXYPYRIDIN-2-AMINE;4-METHOXY-PYRIDIN-2-YLAMINE;KML-35;CML-032;4-Methoxypyridin-2-amin;4-Methoxy-2-pyridinamine;2-PyridinaMine,4-Methoxy;4-Methoxy-2-aMinopyridine;2-AMINO-4-METHOXYPYRIDINE;2-AMINO-4-METHOXYLPYRIDINE

CBNumber:: CB2379186

Molecular Formula:: C6H8N2O

Molecular Weight:: 124.14

MDL Number:: MFCD07437849

MOL File:: 10201-73-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 00:24:45

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2-Amino-4-methoxypyridine Properties

Melting point	120-121°C
Boiling point	258.6±20.0 °C(Predicted)
Density	1.139±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	DMSO, Methanol
pka	7.79±0.11(Predicted)
form	Solid
color	Pale yellow
Water Solubility	Soluble in Dimethyl sulfoxide, methanol. Slightly soluble in water.
Sensitive	Air Sensitive
λmax	280nm(CHCl3)(lit.)
InChI	InChI=1S/C6H8N2O/c1-9-5-2-3-8-6(7)4-5/h2-4H,1H3,(H2,7,8)
InChIKey	QPHBCOSULYSASF-UHFFFAOYSA-N
SMILES	C1(N)=NC=CC(OC)=C1
CAS DataBase Reference	10201-73-7(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P301+P312-P302+P352-P305+P351+P338

target organs

Respiratory system

Hazard Codes

Xi,Xn

Risk Statements

22-36/37/38

Safety Statements

36/37/39

WGK Germany

HazardClass

IRRITANT

HazardClass

6.1

HS Code

2933399990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
2		0

2-Amino-4-methoxypyridine price More Price(91)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	796956	4-Methoxypyridin-2-ylamine 95%	10201-73-7	1g	$13.8	2022-05-15	Buy
TCI Chemical	A2690	2-Amino-4-methoxypyridine >98.0%(GC)(T)	10201-73-7	1g	$35	2026-04-30	Buy
TCI Chemical	A2690	2-Amino-4-methoxypyridine >98.0%(GC)(T)	10201-73-7	5g	$104	2026-04-30	Buy
TRC	TRC-A611995-5G	2-Amino-4-methoxypyridine	10201-73-7	5g	$154	2026-06-03	Buy
TRC	TRC-A611995-2G	2-Amino-4-methoxypyridine	10201-73-7	2g	$109	2026-06-03	Buy

Product number	Packaging	Price	Buy
796956	1g	$13.8	Buy
A2690	1g	$35	Buy
A2690	5g	$104	Buy
TRC-A611995-5G	5g	$154	Buy
TRC-A611995-2G	2g	$109	Buy

2-Amino-4-methoxypyridine Chemical Properties, Uses, Production

Chemical Properties

Pale Yellow Solid

Uses

2-Amino-4-methoxypyridine is a highly selective inducible nitric oxide synthase inhibitors.

Synthesis Reference(s)

The Journal of Organic Chemistry, 72, p. 4554, 2007 DOI: 10.1021/jo070189y

Synthesis

19798-80-2

124-41-4

10201-73-7

General procedure for the synthesis of 2-amino-4-methoxypyridine from 2-amino-4-chloropyridine and sodium methanol: 4-chloropyridin-2-amine (10 g, 78.1 mmol) was dissolved in sodium methanol solution (50 mL, 1 M) in a sealed reaction tube. The reaction mixture was heated at 145 °C for 6 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using 10% dichloromethane solution in methanol as eluent to give 7.7 g (79% yield) of 2-amino-4-methoxypyridine as an off-white solid. Mass spectrometry analysis (ESI): m/z = 125.04 [M + H]+, 281.75 [M/2 + H]+. LCMS retention time: tR = 0.17 min.

References

[1] Patent: WO2015/106292, 2015, A1. Location in patent: Paragraph 00592; 00603; 00604
[2] Journal of Organometallic Chemistry, 1996, vol. 523, # 2, p. 145 - 151
[3] Australian Journal of Chemistry, 1982, vol. 35, # 9, p. 1841 - 1849
[4] Australian Journal of Chemistry, 1982, vol. 35, # 10, p. 2025 - 2034
[5] Patent: WO2012/151137, 2012, A1. Location in patent: Page/Page column 50-51

2-Amino-4-methoxypyridine synthesis

Synthesis of 2-Amino-4-methoxypyridine from 2-Picolinic acid

2-Amino-4-methoxypyridine Preparation Products And Raw materials

Raw materials

Sodium 2-Amino-4-chloropyridine Methanol (4-Methoxy-pyridin-2-yl)-carbamic acid tert-butyl ester 4-Methoxy-pyridine-2-carboxylic acid amide

4-Methoxypyridine N-oxide 2-Bromo-4-methoxypyridine 4-Methoxy-pyridine-2-carboxylic acid methyl ester 2-Picolinic acid Sodium Methoxide

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Preparation Products

[1,2,4]Triazolo[1,5-a]pyridin-7-ol IMidazo[1,2-a]pyridine-3-carboxaldehyde, 7-Methoxy- Imidazo[1,2-a]pyridine, 7-methoxy- (9CI) 2-Aminopyridin-4-ol

2-Amino-4-methoxypyridine Suppliers

Global Suppliers ( 326)

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing Jianuode Pharmaceutical Technology Co., Ltd.	010-67267894 18611880885	gianord@163.com	China	33	58
Shanghai Yaoling Pharmaceutical Technology Partnership (Limited Partnership)	400-6181121 18616383988	edison.li@townyuan.com	China	4762	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
PharmaBlock Sciences (Nanjing),Inc.	025-86918202 4000255188	sales@pharmablock.com	China	5000	55
future industrial shanghai co., ltd	400-0066400 13621662912	sales@jonln.com	China	1989	65
ChemFuture PharmaTech (Jiangsu) Ltd	5108538618	suger.wang@chemfuture.com	China	832	65
TAIYUAN RHF CO.,LTD.	+86 351 7031519	sales@RHFChem.com	China	2334	56
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66

Supplier	Advantage
Beijing Jianuode Pharmaceutical Technology Co., Ltd.	58
Shanghai Yaoling Pharmaceutical Technology Partnership (Limited Partnership)	58
J & K SCIENTIFIC LTD.	76
PharmaBlock Sciences (Nanjing),Inc.	55
future industrial shanghai co., ltd	65
ChemFuture PharmaTech (Jiangsu) Ltd	65
TAIYUAN RHF CO.,LTD.	56
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66

View Latest Price from 2-Amino-4-methoxypyridine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	2-Amino-4-methoxypyridine 10201-73-7	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2026-03-20	2-Amino-4-methoxypyridine 10201-73-7	$8.00-10.00	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2024-03-27	2-Amino-4-methoxy pyridine 10201-73-7	$980.00	1g	98	500 Kg	R&D Scientific Inc.

2-Amino-4-methoxypyridine
10201-73-7
$1.10
99.00%
Dideu Industries Group Limited

2-Amino-4-methoxypyridine
10201-73-7
$8.00-10.00
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-Amino-4-methoxy pyridine
10201-73-7
$980.00
98
R&D Scientific Inc.

2-Amino-4-methoxypyridine Spectrum

2-Amino-4-methoxypyridine(10201-73-7)¹HNMR 2-Amino-4-methoxypyridine(10201-73-7)FT-IR

10201-73-7 (2-Amino-4-methoxypyridine) Related Search:

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N-Ethylmethylamine Triethanolamine 2-Aminophenol Tris(hydroxymethyl)aminomethane Triethylamine

Glycine Aminoethoxyvinyl glycine hydrochloride 4-Aminopyridine

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2-AMINO-4-METHOXYPYRIDINE 4-METHOXY-PYRIDIN-2-YLAMINE 4-Methoxy-Pyridine-2-ylamine 2-AMINO-4-METHOXYLPYRIDINE 4-METHOXY-PYRIDIN-2-YLAMINE, 98.5% 4-Methoxy-2-aMinopyridine 4-(Methyloxy)-2-pyridinaMine 2-PyridinaMine,4-Methoxy 2-AMino-4-Methoxypyridine, 97+% 4-Methoxy-2-pyridinamine CML-032 4-Methoxypyridin-2-amin 4-Methoxypyridin-2-ylamine 95% 2-Amino-4-methoxypyridine > 2-Amino-4-methoxypyridine ISO 9001：2015 REACH KML-35 N,N'-thiocarbonyldiimidazole 4-METHOXYPYRIDIN-2-AMINE 10201-73-7 10201-73-1 Heterocycle-Pyridine series Pyridine pharmacetical Amines Pyridines Amines and Anilines Heterocycles intermediate