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4-Methoxypyridine

4-Methoxypyridine Structure
4-Methoxypyridine structure
CAS No.
620-08-6
Chemical Name:
4-Methoxypyridine
Synonyms
Pyridine, 4-methoxy-;4-Methoxypyridin;4-methoxyridine;4-methoxypridine;4-METHOXYPYRIDINE;4-Methoxypyridine>gamma-Methoxypyridine;4-Methoxypyridine,99%;4-Methoxypyridine 95+%;4-METHOXYPYRIDINE, 98+%
CBNumber:
CB8368991
Molecular Formula:
C6H7NO
Molecular Weight:
109.13
MDL Number:
MFCD00674049
MOL File:
620-08-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:41:01
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4-Methoxypyridine Properties

Melting point 4 °C
Boiling point 108-111 °C/65 mmHg (lit.)
Density 1.075 g/mL at 25 °C (lit.)
refractive index 1.518-1.522
Flash point 74 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Liquid
pka 6.58(at 25℃)
Specific Gravity 1.075
color Clear colorless to slightly yellow
BRN 108211
InChI InChI=1S/C6H7NO/c1-8-6-2-4-7-5-3-6/h2-5H,1H3
InChIKey XQABVLBGNWBWIV-UHFFFAOYSA-N
SMILES C1=NC=CC(OC)=C1
CAS DataBase Reference 620-08-6(CAS DataBase Reference)
NIST Chemistry Reference Pyridine, 4-methoxy-(620-08-6)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-20/21/22
Safety Statements  37/39-26-36-36/37/39
WGK Germany  3
HS Code  29339900
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
2
2 0

4-Methoxypyridine price More Price(75)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 460621 4-Methoxypyridine 97% 620-08-6 5ml $132 2026-04-30 Buy
Sigma-Aldrich 460621 4-Methoxypyridine 97% 620-08-6 25ml $347 2026-04-30 Buy
TCI Chemical M1696 4-Methoxypyridine >98.0%(GC)(T) 620-08-6 5g $27 2026-04-30 Buy
TCI Chemical M1696 4-Methoxypyridine >98.0%(GC)(T) 620-08-6 25g $110 2026-04-30 Buy
TRC TRC-M267145-5G 4-Methoxypyridine 620-08-6 5g $142 2026-06-03 Buy
Product number Packaging Price Buy
460621 5ml $132 Buy
460621 25ml $347 Buy
M1696 5g $27 Buy
M1696 25g $110 Buy
TRC-M267145-5G 5g $142 Buy

4-Methoxypyridine Chemical Properties, Uses, Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

4-Methoxypyridine, is used as a building block for the synthesis of some biologically active compounds. It is used for the preparation of a new series of benzoylated N-ylides as protein farnesyltransferase inhibitors.

Uses

4-Methoxypyridine was used as a starting reagent for the stereocontrolled synthesis of (±)-pumiliotoxin C and (±)-lasubine II. It was also used in an efficient construction of dihyropyridin-4-ones, which serves as potential ligands for neuronal nicotinic acetycholine receptors.

General Description

4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied.

Synthesis

At room temperature, (50mmo1) 4-methoxypyridine-N-oxide was dissolved in 50mL acetonitrile solution, then 1.01g (55mmo1) tritiated cyanogen chloride (TCT) was added to the reaction solution in batches, and the reaction was tracked by TCL, and at the end of the reaction, 20mL of saturated sodium carbonate solution was added dropwise to the reaction solution, and the reaction was stirred for 30min. dichloromethane was added to extract, and the organic phase was respectively The organic phase was washed with water and saturated saline, and the crude product was obtained by spinning off the solvent under reduced pressure. The crude product was purified by column to get the target product. Light yellow oily liquid.

 

4-Methoxypyridine synthesis

1122-96-9
620-08-6
Synthesis of 4-Methoxypyridine from 4-Methoxypyridine N-oxide

4-Methoxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

4-n-Decylpyridine 3,4-Dimethoxy-2-Methylpyridine 4-Methoxypiperidine 3-Bromo-4-methoxy-pyridine 2-Bromo-4-methoxypyridine
4-Methoxypyridine N-oxide Benzyl 2-n-propyl-4-oxo-3,4-dihydropyridine-1(2H)-carboxylate benzyl 3,4-dihydro-4-oxo-2-phenylpyridine-1(2H)-carboxylate Phenyl 4-oxo-2-phenyl-3,4-dihydropyridine-1(2H)-carboxylate 3-Pyridinecarboxaldehyde, 4-methoxy-5-methyl- (9CI)

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4-Methoxypyridine Suppliers

Global Suppliers ( 424)
Supplier Tel Email Country ProdList Advantage
China Shenyang Tyschem CO. ,LTD +86-024-83607930 18640359690 sales@honghuchem.com China 256 58
Fuxin Custchem Fine Chemical Co., Ltd. 0418-5113999 18740177324 sales@custchem.com.cn China 448 58
Hunan Daolin Biotechnology Co. , Ltd. 18974846212 1876969603@qq.com China 57 58
Jiangxi Hechun Pharmaceutical Technology Co., Ltd. 13033833208 3692193759@qq.com China 72 58
Jiangxi Bairui Technology Co., Ltd 13026208279 13026208279 bwinchem@163.com China 186 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Supplier Advantage
China Shenyang Tyschem CO. ,LTD 58
Fuxin Custchem Fine Chemical Co., Ltd. 58
Hunan Daolin Biotechnology Co. , Ltd. 58
Jiangxi Hechun Pharmaceutical Technology Co., Ltd. 58
Jiangxi Bairui Technology Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84

View Latest Price from 4-Methoxypyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methoxypyridine pictures 2026-09-02 4-Methoxypyridine
620-08-6
 $6.00 1KG 98% Henan Fengda Chemical Co., Ltd
4-Methoxypyridine pictures 2026-08-20 4-Methoxypyridine
620-08-6
 $1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
4-Methoxypyridine pictures 2026-06-30 4-Methoxypyridine
620-08-6
 1KG 99.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd

4-Methoxypyridine Spectrum

4-Methoxypyridine(620-08-6)MS4-Methoxypyridine(620-08-6)1HNMR4-Methoxypyridine(620-08-6)13CNMR4-Methoxypyridine(620-08-6)IR

620-08-6 (4-Methoxypyridine) Related Search:

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gamma-Methoxypyridine 4-METHOXYPYRIDINE METHYL PYRIDIN-4-YL ETHER 4-METHOXYPYRIDINE, 98+% 4-methoxypridine Pyridine, 4-methoxy- 4-Methoxypyridine, 99% 5ML 4-Methoxypyridine,99% 4-methoxyridine 4-Methoxypyridin 4-Methoxypyridine, 97.5% 4-Methoxypyridine 95+% 4-Methoxypyridine, 97+% butyl 2-bromo-2-methylpropanoate 4-Methoxypyridine> 4-Methoxypyridine, 98%, for synthesis 4-Methoxypyridine ISO 9001：2015 REACH 620-08-6 210-624-7 135567-40-4 137238-62-6 Heterocyclic Building Blocks Pyridines Building Blocks C6 Heterocyclic Building Blocks Pyridines, Pyrimidines, Purines and Pteredines Boronic Acid Pyridine Derivertives Pyridine series blocks Pyridines Pyridine C6