1-Indolepropionic acid
- CAS No.
- 6639-06-1
- Chemical Name:
- 1-Indolepropionic acid
- Synonyms
- 1-Indolepropionic acid;Indole-1-propionic acid;B-N-INDOLEPROPIONIC ACID;1H-indole-1-propanoic acid;3-indol-1-ylpropionic acid;3-indol-1-ylpropanoic acid;3-(1-indolyl)propanoic acid;BETA-N-INDOLE PROPIONIC ACID;3-(1H-INDOL-1-YL)PROPANOIC ACID
- CBNumber:
- CB2379252
- Molecular Formula:
- C11H11NO2
- Molecular Weight:
- 189.21
- MDL Number:
- MFCD00022896
- MOL File:
- 6639-06-1.mol
- MSDS File:
- SDS
| Melting point | 91 °C |
|---|---|
| Boiling point | 180-197 °C |
| Density | 1.19±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 4.59±0.10(Predicted) |
| FDA UNII | HN7XR99LDF |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| HazardClass | IRRITANT |
| HS Code | 2933998090 |
1-Indolepropionic acid price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S540390 | 1-INDOLEPROPIONIC ACID AldrichCPR | 6639-06-1 | 1 unit | $197 | 2026-04-30 | Buy |
| Sigma-Aldrich | S540390 | 1-INDOLEPROPIONIC ACID AldrichCPR | 6639-06-1 | 1G | $179 | 2024-03-01 | Buy |
| Apolloscientific | OR930793 | 3-(1H-Indol-1-yl)propanoic acid 98% | 6639-06-1 | 250mg | $79 | 2026-06-04 | Buy |
| Apolloscientific | OR930793 | 3-(1H-Indol-1-yl)propanoic acid 98% | 6639-06-1 | 1g | $98 | 2026-06-04 | Buy |
| Apolloscientific | OR930793 | 3-(1H-Indol-1-yl)propanoic acid 98% | 6639-06-1 | 5g | $294 | 2026-06-04 | Buy |
1-Indolepropionic acid Chemical Properties, Uses, Production
Synthesis
120-72-9
3395-91-3
6639-06-1
General procedure for the synthesis of 1-indolepropionic acid from indole and methyl 3-bromopropionate: Synthesis of 3-(1H-indol-1-yl)propionic acid (Intermediate-25): 10 mL of DMF was added to a 100 mL round bottom flask fitted with a magnetic stirrer. to the stirred solvent was added indole (1.0 g, 8.53 mmol) followed by sodium hydride (400 mg, 10.24 mmol). The resulting mixture was stirred at room temperature for 1 hr. Methyl 3-bromopropionate (2.13 g, 12.79 mmol) was added to the above reaction solution and stirring was continued for 24 hours at room temperature. After completion of the reaction (the progress of the reaction was monitored by TLC), the reaction mixture was diluted with 30 mL of ice water and washed with ether. The aqueous phase was acidified with 1N HCl to pH=2 and subsequently extracted with EtOAc and concentrated to give Intermediate-24 (900 mg).
References
[1] Patent: WO2013/128465, 2013, A1. Location in patent: Page/Page column 94
[2] Patent: US2015/158860, 2015, A1. Location in patent: Paragraph 0332
[3] Patent: WO2004/43899, 2004, A1. Location in patent: Page 37; 38
1-Indolepropionic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1-Indolepropionic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| SpringPharma Tech Co.,Ltd | +86-25-68710855, +86-25-68710897 | sales@springpharma.net | China | 1260 | 62 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4904 | 55 |
| Nantong Bosu Pharmaceutical Technology Co., Ltd. | 0513-51005092 15962844273 | tashiyxy@163.com | China | 914 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89664 | 60 |
| Shanghai Anmike Chemical Co. Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 9988 | 55 |
| 9ding chemical ( Shanghai) Limited | 021-021-52271985 17721149837 | sales@9dingchem.com | China | 19780 | 60 |
| Aikon International Limited | 025-58859352 19370895928 | sales01@aikonchem.com | China | 15078 | 58 |
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