Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate
- CAS No.
- 76360-82-2
- Chemical Name:
- Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate
- Synonyms
- NSC 165300;-2-(methylsulfanyl);Ethyl 4-(methylamino);-5-pyrimidinecarboxylate;Ethyl 4-(MethylaMino)-2-(Methylthio)pyriMidine-5-carboxylate;ethyl 2-(Methylthio)-4-(MethylaMino)-pyriMidine-5-carboxylate;2-(Methylthio)-4-(MethylaMino)-pyriMidine-5-carboxylic acid e;ethyl 4-(MethylaMino)-2-(Methylsulfanyl)pyriMidine-5-carboxylate;Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate;4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic Acid Ethyl Ester
- CBNumber:
- CB2401092
- Molecular Formula:
- C9H13N3O2S
- Molecular Weight:
- 227.28
- MDL Number:
- MFCD00476788
- MOL File:
- 76360-82-2.mol
- MSDS File:
- SDS
| Melting point | 91-93 °C |
|---|---|
| Boiling point | 368.9±22.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform, Dichloromethane, DMSO, Ethyl Acetate, Methanol |
| pka | 3.11±0.10(Predicted) |
| form | Solid |
| color | White |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P305+P351+P338 |
Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 016503 | 4-(Methylamino)-2-(methylthio)pyrimidine-5-carboxylic Acid Ethyl Ester | 76360-82-2 | 250mg | $446 | 2026-06-03 | Buy |
| Matrix Scientific | 132422 | Ethyl 4-(methylamino)-2-(methylthio)-pyrimidine-5-carboxylate | 76360-82-2 | 5.00g | $1224 | 2026-05-18 | Buy |
| Matrix Scientific | 132422 | Ethyl 4-(methylamino)-2-(methylthio)-pyrimidine-5-carboxylate | 76360-82-2 | 10.00g | $1764 | 2026-05-18 | Buy |
| Synthonix | E50330 | Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate 97% | 76360-82-2 | 100mg | $25 | 2026-05-06 | Buy |
| Synthonix | E50330 | Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate 97% | 76360-82-2 | 250mg | $30 | 2026-05-06 | Buy |
Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate Chemical Properties, Uses, Production
Chemical Properties
White Solid
Uses
An intermediate in the preparation of antitumor agents, antiinflammatory agents and tyrosine kinase inhibitors
Synthesis
5909-24-0
74-89-5
76360-82-2
A 33% aqueous methylamine solution (17.5 mL, 140 mmol) was slowly added dropwise to a dichloromethane solution (120 mL) containing ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate (10.0 g, 43.1 mmol) at 0 °C. The reaction mixture was stirred at this temperature for 30 minutes. The reaction mixture was stirred at this temperature for 30 minutes. Subsequently, it was quenched by the addition of water (150 mL), the organic phase was separated and dried over anhydrous magnesium sulfate. After filtration, the filtrate was concentrated under reduced pressure to afford the product ethyl 4-methylamino-2-methylthio-5-pyrimidinecarboxylate (9.77 g, 100% yield) as a white solid.
References
[1] Patent: WO2014/144737, 2014, A1. Location in patent: Paragraph 00719
[2] Patent: WO2015/19037, 2015, A1. Location in patent: Page/Page column 87; 88
[3] Patent: US2003/207900, 2003, A1. Location in patent: Page/Page column 15
[4] Journal of Medicinal Chemistry, 2010, vol. 53, # 15, p. 5439 - 5448
[5] Journal of Medicinal Chemistry, 2011, vol. 54, # 7, p. 2255 - 2265
Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate Preparation Products And Raw materials
Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3830 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| CEG Chemical Science&Technology Co., Ltd. | Mobile:13665161512 | China | 1784 | 58 | |
| Tianjin Englon Technology Co., LTD | 010-010-1234567 17526513758 | 2062435649@qq.com | China | 97 | 49 |
| Shanghai SunSyn Pharmaceutical Co., Ltd. | 021-18621020637 18621020637 | sales@sunsynpharma.com | China | 297 | 55 |
| Taizhou Tongxin Bio-Tech Co., Ltd | 0523-86818997 18652728585 | sales@allyrise.com | China | 2986 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
View Latest Price from Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | ETHYL 4-(METHYLAMINO)-2-(METHYLSULFANYL)-5-PYRIMIDINECARBOXYLATE
76360-82-2
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-01-10 | ethyl 4-(methylamino)-2-methylsulfanylpyrimidine-5-carboxylate
76360-82-2
|
$1.00 | 1g | 95-99% | 1ton | Career Henan Chemical Co |
-
- ETHYL 4-(METHYLAMINO)-2-(METHYLSULFANYL)-5-PYRIMIDINECARBOXYLATE
76360-82-2
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- ethyl 4-(methylamino)-2-methylsulfanylpyrimidine-5-carboxylate
76360-82-2
- $1.00
- 95-99%
- Career Henan Chemical Co
76360-82-2 (Ethyl 4-(methylamino)-2-(methylsulfanyl)-5-pyrimidinecarboxylate) Related Search:
1of4
