(2S)-Bornane-10,2-sultam
- CAS No.
- 108448-77-7
- Chemical Name:
- (2S)-Bornane-10,2-sultam
- Synonyms
- (+)-10,2-CAMPHORSULTAM;2-sultaM;(+)-10,2-Camphorsultam;(7aS)-8,8-Dimethylhexahydro-1H-3a,6-methanobenzo[c]isothiazole 2,2-dioxide;L-SultaM;(2S)-Bornane-10;L-2,10-amphorsultam;D-(-)-CAMPHOR SULTAM;(2S)-Borne-10,2-sultam;(1R)-(+)-Camphorsultam
- CBNumber:
- CB2411257
- Molecular Formula:
- C10H17NO2S
- Molecular Weight:
- 215.31
- MDL Number:
- MFCD00151762
- MOL File:
- 108448-77-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (+)-10,2-Camphorsultam >98.0%(GC) | C1324 | 1g | $94 |
| (+)-10,2-Camphorsultam >98.0%(GC) | C1324 | 5g | $325 |
| (+)-10,2-Camphorsultam Asreported | 270510 | 500mg | $306 |
| (+)-10,2-Camphorsultam Asreported | 270510 | 1g | $420 |
| (+)-10,2-Camphorsultam Asreported | 270510 | 2g | $568 |
| More product size | |||
| Melting point | 185-187 °C(lit.) |
|---|---|
| alpha | 33 º (c=4.9, CHCl3) |
| Boiling point | 324.8±25.0 °C(Predicted) |
| Density | 1.1469 (rough estimate) |
| refractive index | 31 ° (C=1, CHCl3) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | almost transparency in Chloroform |
| pka | 11.05±0.40(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| optical activity | [α]20/D +32°, c = 5 in chloroform |
| BRN | 4675755 |
| InChI | InChI=1S/C10H17NO2S/c1-9(2)7-3-4-10(9)6-14(12,13)11-8(10)5-7/h7-8,11H,3-6H2,1-2H3/t7-,8-,10-/m0/s1 |
| InChIKey | DPJYJNYYDJOJNO-CFGJQEBVSA-N |
| SMILES | N1[C@]2([H])[C@@]3(C(C)(C)[C@]([H])(C2)CC3)CS1(=O)=O |
| CAS DataBase Reference | 108448-77-7(CAS DataBase Reference) |
| UNSPSC Code | 12352005 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P304+P340-P405-P501a-P261-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29242990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
(2S)-Bornane-10,2-sultam price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C1324 | (+)-10,2-Camphorsultam >98.0%(GC) | 108448-77-7 | 1g | $94 | 2021-12-16 | Buy |
| TCI Chemical | C1324 | (+)-10,2-Camphorsultam >98.0%(GC) | 108448-77-7 | 5g | $325 | 2026-04-30 | Buy |
| Usbiological | 270510 | (+)-10,2-Camphorsultam Asreported | 108448-77-7 | 500mg | $306 | 2026-06-03 | Buy |
| Usbiological | 270510 | (+)-10,2-Camphorsultam Asreported | 108448-77-7 | 1g | $420 | 2026-06-03 | Buy |
| Usbiological | 270510 | (+)-10,2-Camphorsultam Asreported | 108448-77-7 | 2g | $568 | 2026-06-03 | Buy |
(2S)-Bornane-10,2-sultam Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
(1R)-(+)-2,10-Camphorsultam has been used as a reactant in the synthesis of pyrrolidine acid analogs as potent dual PPARα/γ agonists.
Application
(2S)-Bornane-10,2-sultam is a pharmaceutical intermediate compound that can be used to synthesize sulfonamide drugs. (2R)-Bornane-10,2-sultam can be used as a chiral auxiliary to perform intramolecular 1,3-dipolar cycloadditions to generate bridged and fused cycloadditions with complete diastereocontrol. Reduction of fused isoxazolidines can generate 1-azaspiro[4.5]decane, which is a potential intermediate in the asymmetric synthesis of cylindrosin alkaloids[1].
Purification Methods
The (-)-enantiomer is recrystallised from 95% EtOH and dried in a vacuum desiccator. It dissolves in dilute aqueous NaOH and can be precipitated without hydrolysis by acidifying. It forms the N-Na salt in EtOH (by addition of Na to the EtOH solution), and the salt can be methylated with MeI to give the (-)-N-Me lactam with m 80o after recrystallisation from hot H2O and has []D -59.6o (c 5, CHCl3) [Shriner et al. J Am Chem Soc 60 2794 1938]. [Oppolzer et al. Helv Chim Acta 69 1142 1986, Weismiller et al. Org Synth 69 154 1955, Beilstein 27 III/IV 1007.]
References
[1] MARK C BAGLEY; Wolfgang O. Asymmetric synthesis of 1-azaspiro[4.5]decanes via intramolecular dipolar cycloaddition of nitrones containing the bornane-10,2-sultam chiral auxiliary[J]. Tetrahedron, asymmetry, 2000. DOI:10.1016/S0957-4166(00)00205-6.
(2S)-Bornane-10,2-sultam Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Chontech Baocheng Chemical Co.,Ltd | +86-51982698291; +86-15295095616 | info@hhbhswkj.com | China | 131 | 58 |
| Accendatech Co., Ltd. | +undefined+86-13132578992 | yunhao.liu@accendatech.com | China | 250 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14036 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
View Lastest Price from (2S)-Bornane-10,2-sultam manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-16 | (1R)-(+)-2,10-Camphorsultam
108448-77-7
|
$1.00 | 1g | 99% | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | |
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2025-11-18 | (2S)-Bornane-10,2-sultam
108448-77-7
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2023-02-18 | (1R)-(+)-2,10-Camphorsultam
108448-77-7
|
1kg | 98% | Aromsyn Co., Ltd. |
-

- (1R)-(+)-2,10-Camphorsultam
108448-77-7
- $1.00
- 99%
- Zibo Hangyu Biotechnology Development Co., Ltd
-

- (2S)-Bornane-10,2-sultam
108448-77-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- (1R)-(+)-2,10-Camphorsultam
108448-77-7
- 98%
- Aromsyn Co., Ltd.
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