ChemicalBook >> CAS DataBase List >>(2S)-Bornane-10,2-sultam

(2S)-Bornane-10,2-sultam

CAS No.
108448-77-7
Chemical Name:
(2S)-Bornane-10,2-sultam
Synonyms
(+)-10,2-CAMPHORSULTAM;2-sultaM;(+)-10,2-Camphorsultam;(7aS)-8,8-Dimethylhexahydro-1H-3a,6-methanobenzo[c]isothiazole 2,2-dioxide;L-SultaM;(2S)-Bornane-10;L-2,10-amphorsultam;D-(-)-CAMPHOR SULTAM;(2S)-Borne-10,2-sultam;(1R)-(+)-Camphorsultam
CBNumber:
CB2411257
Molecular Formula:
C10H17NO2S
Molecular Weight:
215.31
MDL Number:
MFCD00151762
MOL File:
108448-77-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 00:35:56
Product description Number Pack Size Price
(+)-10,2-Camphorsultam >98.0%(GC) C1324 1g $94
(+)-10,2-Camphorsultam >98.0%(GC) C1324 5g $325
(+)-10,2-Camphorsultam Asreported 270510 500mg $306
(+)-10,2-Camphorsultam Asreported 270510 1g $420
(+)-10,2-Camphorsultam Asreported 270510 2g $568
More product size

(2S)-Bornane-10,2-sultam Properties

Melting point 185-187 °C(lit.)
alpha 33 º (c=4.9, CHCl3)
Boiling point 324.8±25.0 °C(Predicted)
Density 1.1469 (rough estimate)
refractive index 31 ° (C=1, CHCl3)
storage temp. Sealed in dry,Room Temperature
solubility almost transparency in Chloroform
pka 11.05±0.40(Predicted)
form powder to crystal
color White to Almost white
optical activity [α]20/D +32°, c = 5 in chloroform
BRN 4675755
InChI InChI=1S/C10H17NO2S/c1-9(2)7-3-4-10(9)6-14(12,13)11-8(10)5-7/h7-8,11H,3-6H2,1-2H3/t7-,8-,10-/m0/s1
InChIKey DPJYJNYYDJOJNO-CFGJQEBVSA-N
SMILES N1[C@]2([H])[C@@]3(C(C)(C)[C@]([H])(C2)CC3)CS1(=O)=O
CAS DataBase Reference 108448-77-7(CAS DataBase Reference)
UNSPSC Code 12352005

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P280a-P304+P340-P405-P501a-P261-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HS Code  29242990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

(2S)-Bornane-10,2-sultam price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C1324 (+)-10,2-Camphorsultam >98.0%(GC) 108448-77-7 1g $94 2021-12-16 Buy
TCI Chemical C1324 (+)-10,2-Camphorsultam >98.0%(GC) 108448-77-7 5g $325 2026-04-30 Buy
Usbiological 270510 (+)-10,2-Camphorsultam Asreported 108448-77-7 500mg $306 2026-06-03 Buy
Usbiological 270510 (+)-10,2-Camphorsultam Asreported 108448-77-7 1g $420 2026-06-03 Buy
Usbiological 270510 (+)-10,2-Camphorsultam Asreported 108448-77-7 2g $568 2026-06-03 Buy
Product number Packaging Price Buy
C1324 1g $94 Buy
C1324 5g $325 Buy
270510 500mg $306 Buy
270510 1g $420 Buy
270510 2g $568 Buy

(2S)-Bornane-10,2-sultam Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

(1R)-(+)-2,10-Camphorsultam has been used as a reactant in the synthesis of pyrrolidine acid analogs as potent dual PPARα/γ agonists.

Application

(2S)-Bornane-10,2-sultam is a pharmaceutical intermediate compound that can be used to synthesize sulfonamide drugs.  (2R)-Bornane-10,2-sultam can be used as a chiral auxiliary to perform intramolecular 1,3-dipolar cycloadditions to generate bridged and fused cycloadditions with complete diastereocontrol.  Reduction of fused isoxazolidines can generate 1-azaspiro[4.5]decane, which is a potential intermediate in the asymmetric synthesis of cylindrosin alkaloids[1].

Purification Methods

The (-)-enantiomer is recrystallised from 95% EtOH and dried in a vacuum desiccator. It dissolves in dilute aqueous NaOH and can be precipitated without hydrolysis by acidifying. It forms the N-Na salt in EtOH (by addition of Na to the EtOH solution), and the salt can be methylated with MeI to give the (-)-N-Me lactam with m 80o after recrystallisation from hot H2O and has []D -59.6o (c 5, CHCl3) [Shriner et al. J Am Chem Soc 60 2794 1938]. [Oppolzer et al. Helv Chim Acta 69 1142 1986, Weismiller et al. Org Synth 69 154 1955, Beilstein 27 III/IV 1007.]

References

[1] MARK C BAGLEY; Wolfgang O. Asymmetric synthesis of 1-azaspiro[4.5]decanes via intramolecular dipolar cycloaddition of nitrones containing the bornane-10,2-sultam chiral auxiliary[J]. Tetrahedron, asymmetry, 2000. DOI:10.1016/S0957-4166(00)00205-6.

107869-45-4
108448-77-7
Synthesis of (2S)-Bornane-10,2-sultam from (+)-10-CAMPHORSULFONIMINE

(2S)-Bornane-10,2-sultam Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 281)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Chontech Baocheng Chemical Co.,Ltd
+86-51982698291; +86-15295095616 info@hhbhswkj.com China 131 58
Accendatech Co., Ltd.
+undefined+86-13132578992 yunhao.liu@accendatech.com China 250 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29626 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 14036 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32997 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29766 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63645 58
CONIER CHEM AND PHARMA LIMITED
sales@conier.com China 49906 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21135 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780 sale@simagchem.com China 17339 58

View Lastest Price from (2S)-Bornane-10,2-sultam manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(1R)-(+)-2,10-Camphorsultam pictures 2026-08-16 (1R)-(+)-2,10-Camphorsultam
108448-77-7
$1.00 1g 99% 20tons Zibo Hangyu Biotechnology Development Co., Ltd
(2S)-Bornane-10,2-sultam  pictures 2025-11-18 (2S)-Bornane-10,2-sultam
108448-77-7
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
(1R)-(+)-2,10-Camphorsultam pictures 2023-02-18 (1R)-(+)-2,10-Camphorsultam
108448-77-7
1kg 98% Aromsyn Co., Ltd.
(7aS)-8,8-Dimethylhexahydro-1H-3a,6-methanobenzo[c]isothiazole 2,2-dioxide (2S)-Borne-10,2-sultam L-2,10-Camphorsultam,99%e.e. (2S)-BORNANE-10,2-SULTAM (1R)-(+)-2,10-CAMPHORSULTAM (1R)-2,10-CAMPHORSULTAM (1R,2S)-(+)-2,10-CAMPHORSULTAM (1R,5S)-10,10-DIMETHYL-3-THIA-4-AZATRICYCLO[5.2.1.01,5]DECANE 3,3-DIOXIDE (IR)-(+)-2,10-Camphorsultam (1R)-(+)-2,10-camphorsultam ,98% L-2,10-amphorsultam (2S)-Bornane-10 (2S)-Bornane-1,2-sultaM L-SultaM (2S)-Bornane-10,2-sultam (1R,5S)-10,10-Dimethyl-3-thia-4-azatricyclo[5.2.1.0(1,5)]decane 3,3-Dioxide (1R)-(+)-2,10-Camphorsultam (5S,7S)-10,10-dimethyl-3λ-thia-4-azatricyclo[5.2.1.01,]decane-3,3-dione (2S)-Bornane-10,2-sultam (1R)-(+)-2,10-Camphorsultam [3AR-(3A-ALPHA,6-ALPHA,7A-BETA)]-HEXAHYDRO-8,8-DIMETHYL-2,2-DIOXIDE-3H-3A,6-METHANO-2,1-BENZISOTHIAZOLE [3aR-(3aalpha,6alpha,7abeta)]-Hexahydro-8,8-dimethyl-2,2-dioxide-3H-3a,6-methano-2,1-benzisothiazole (+)-EXO-10,2-BORNANESULTAM (+)-L-2,10-CAMPHORSULTAM L(+)-10,2-CAMPHORSULTAME D-(-)-CAMPHOR SULTAM (+)-2,10-CAMPHORSULTAM 99% (2S)-Bornane-10,2-sultam,99+%, (99+% ee) (2S)-Bornane-10,2-sultam,98% (+)-exo-10,2-Bornanesultam, (1R,5S)-10,10-Dimethyl-3-thia-4-azatricyclo[5.2.1.01,5]decane 3,3-dioxide (+)-10,2-Camphorsultam, (+)-exo-10,2-Bornanesultam, L-2,10-Camphorsultam, (1R,5S)-10,10-Dimethyl-3-thia-4-azatricyclo[5.2.1.01,5]decane 3,3-dioxide (1β,5α,7β)-10,10-Dimethyl-3-thia-4-azatricyclo[5.2.1.01,5]decane3,3-dioxide (3aR)-1,4,5,6,7,7aβ-Hexahydro-8,8-dimethyl-3H-3aα,6α-methano-2,1-benzisothiazole 2,2-dioxide (3aR,3aα,6α,7aβ)-8,8-Dimethyl-3a,6-methanooctahydro-2,1-benzisothiazole 2,2-dioxide [3aR,7aβ,(+)]-Hexahydro-8,8-dimethyl-3H-3aα,6α-methano-2,1-benzisothiazole 2,2-dioxide (1R)-(+)-Camphorsultam (1R,2S)-(+)-10,2-Camphorsultam (1R,2S)-(+)-10,2-CamphorsuL 3H-3a,6-Methano-2,1-benzisothiazole, hexahydro-8,8-dimethyl-, 2,2-dioxide, (3aR,6S,7aS)- (3aR)-8,8-dimethylhexahydro-2H-3a,6-methanobenzo[d]isothiazole 1,1-dioxide (2S)-Bornane-10,2-sultam ISO 9001:2015 REACH (3aR,6S,7aS)-8,8-Dimethylhexahydro-1H-3a,6-methanobenzo[c]isothiazole 2,2-dioxide (5S,7S)-10,10-dimethyl-3λ?-thia-4-azatricyclo[5.2.1.01?]decane 3,3-dioxide (+)-2,10-Camphorsultam L-(+)-Camphor sulfonamide (+)-10,2-Camphorsultam (+)-10,2-CAMPHORSULTAM 2-sultaM 108448-77-7 C10H17NO2S Sulfur-Based Sulfur Compounds (for Synthesis) Bicyclic Monoterpenes Terpenes Asymmetric Synthesis Chiral Auxiliaries chiral Asymmetric Synthesis Bicyclic Monoterpenes Biochemistry